Investigation of protein/carbohydrate interactions in the dried state. 2. Diffuse reflectance FTIR studies

International Journal of Pharmaceutics

Volumn 235, Issue 1-2, 2002, Pages 207-218

  Souillac, Pierre O ^a   Middaugh, C Russell ^a   Rytting, J Howard ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

Carbohydrate; Freeze drying; FTIR; Protein; Solid state

Indexed keywords

CARBOHYDRATE; DEXTRAN; DORNASE ALFA; MANNITOL; RECOMBINANT SOMATOMEDIN C; SUCROSE; TREHALOSE;

ALPHA HELIX; ARTICLE; BETA SHEET; CIRCULAR DICHROISM; CONCENTRATION RESPONSE; DIFFUSE REFLECTANCE SPECTROSCOPY; DRUG FORMULATION; DRUG PELLET; FREEZE DRYING; INFRARED SPECTROSCOPY; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE;

CARBOHYDRATES; CHEMISTRY, PHARMACEUTICAL; DEOXYRIBONUCLEASE I; EXPECTORANTS; FREEZE DRYING; INSULIN-LIKE GROWTH FACTOR I; PROTEINS; RECOMBINANT PROTEINS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 0037139368     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(01)00987-5     Document Type: Article

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