Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport

Journal of Cell Biology

Volumn 158, Issue 4, 2002, Pages 681-693

  Rao, Mala V ^a,f   Garcia, Michael L ^b,c   Miyazaki, Yukio ^b,c   Gotow, Takahiro ^d   Yuan, Aidong ^a   Mattina, Salvatore ^a   Ward, Chris M ^b,c   Calcutt, Nigel A ^b   Uchiyama, Yasuo ^e   Nixon, Ralph A ^a   Cleveland, Don W ^b,c  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d KOSHIEN UNIVERSITY   (Japan)

^e OSAKA UNIVERSITY   (Japan)

^f NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

Author keywords

Axonal transport; Conduction velocity; Neurofilaments; NF H phosphorylation; Radial growth

Indexed keywords

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; GENE REPLACEMENT THERAPY; MOLECULAR DYNAMICS; MOUSE; NERVE FIBER TRANSPORT; NEUROFILAMENT; NONHUMAN; OPTIC NERVE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN PHOSPHORYLATION; SCIATIC NERVE; TRANSPORT KINETICS;

ACTION POTENTIALS; AMINO ACID SUBSTITUTION; ANIMALS; AXONAL TRANSPORT; AXONS; CELL DIVISION; CELLS, CULTURED; GENE DELETION; MICE; MICROTUBULES; MYELIN SHEATH; NEUROFILAMENT PROTEINS; NEURONS, AFFERENT; PHOSPHORYLATION; PROTEIN SUBUNITS; REPETITIVE SEQUENCES, AMINO ACID; TUBULIN;

ANIMALIA; MAMMALIA;

EID: 0037135978     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200202037     Document Type: Article

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