Synthesis and opioid activity of new fentanyl analogs

Life Sciences

Volumn 71, Issue 9, 2002, Pages 1023-1034

  Girón, Rocío ^a   Abalo, Raquel ^a   Goicoechea, Carlos ^a   Martín, Ma Isabel ^a   Callado, Luis F ^b   Cano, Carolina ^c   Goya, Pilar ^c   Jagerovic, Nadine ^c  

^a UNIVERSIDAD REY JUAN CARLOS   (Spain)

^b UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^c INSTITUTO DE QUÍMICA MÉDICA   (Spain)

Author keywords

Fentanyl analog; In vitro assay; New analgesics; Nociception; Opioid receptor

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE; ANALGESIC AGENT; DELTA OPIATE RECEPTOR AGONIST; DELTA OPIATE RECEPTOR ANTAGONIST; DEXTRO PHENYLALANYLCYSTEINYLTYROSYL DEXTRO TRYPTOPHYLORNITHYLTHREONYLPENICILLAMINYLTHREONINAMIDE 2,7 DISULFIDE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; FENTANYL; FENTANYL DERIVATIVE; KAPPA OPIATE RECEPTOR AGONIST; MORPHINE; MU OPIATE RECEPTOR AGONIST; MU OPIATE RECEPTOR ANTAGONIST; N (1 PHENYLPYRAZOL 3 YL) N [1 (2 PHENETHYL) 4 PIPERIDYL]PROPANAMIDE; N (2 BIPHENYL) N [1 (2 PHENETHYL) 4 PIPERIDYL)]PROPANAMIDE; N [1 (4 FLUOROPHENYL)PYRAZOL 3 YL] N (1 BENZYL 4 PIPERIDYL)PROPANAMIDE; N METHYL N [7 (1 PYRROLIDINYL) 1 OXASPIRO[4.5]DEC 8 YL]BENZENEACETAMIDE; NALOXONE; NALTRINDOLE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; EVOKED MUSCLE RESPONSE; HOT PLATE TEST; ILEUM; MALE; MOUSE; MUSCLE CONTRACTION; MYENTERIC PLEXUS; NONHUMAN; RECEPTOR AFFINITY; VAS DEFERENS;

ANALGESICS, OPIOID; ANIMALS; FENTANYL; GUINEA PIGS; ILEUM; MALE; MICE; MUSCLE CONTRACTION; RABBITS; RECEPTORS, OPIOID, MU; SPECIES SPECIFICITY; VAS DEFERENS;

CAVIA PORCELLUS; ORYCTOLAGUS CUNICULUS; SUS SCROFA;

EID: 0037135247     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(02)01798-8     Document Type: Article

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