Stable oligonucleotide-directed triplex formation at target sites with CG interruptions: Strong sequence-specific recognition by 2′,4′-bridged nucleic-acid-containing 2-pyridones under physiological conditions

Chemistry - A European Journal

Volumn 8, Issue 20, 2002, Pages 4796-4802

  Obika, Satoshi ^a   Hari, Yoshiyuki ^a   Sekiguchi, Mitsuaki ^a   Imanishi, Takeshi ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Molecular recognition; Nucleic acids; Nucleobases; Oligonucleotides

Indexed keywords

DNA; MONOMERS; PHYSIOLOGY; SODIUM COMPOUNDS;

TRIPLEX-FORMING OLIGONUCLEOTIDES (TFO);

ORGANIC ACIDS;

2 HYDROXYPYRIDINE; 2 PYRIDONE DERIVATIVE; 2-HYDROXYPYRIDINE; BRIDGED COMPOUND; CYTOSINE; DNA; DOUBLE STRANDED DNA; GUANINE; MONOMER; NUCLEIC ACID; NUCLEIC ACID BASE; NUCLEOSIDE; OLIGONUCLEOTIDE; POTASSIUM CHLORIDE; PURINE; PYRIDONE DERIVATIVE; PYRIMIDINE; RIBONUCLEOTIDE; SODIUM DIHYDROGEN PHOSPHATE; SPERMINE; TRIPLEX DNA;

ARTICLE; BASE PAIRING; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CHEMISTRY; GENE EXPRESSION REGULATION; GENE TARGETING; MELTING POINT; MOLECULAR RECOGNITION; MOLECULAR STABILITY; NUCLEOTIDE SEQUENCE; PH; SYNTHESIS; TEMPERATURE; ULTRAVIOLET RADIATION;

BASE PAIRING; BASE SEQUENCE; BRIDGED COMPOUNDS; DNA; HYDROGEN-ION CONCENTRATION; MOLECULAR STRUCTURE; NUCLEIC ACIDS; NUCLEOSIDES; OLIGONUCLEOTIDES; PYRIDONES; TEMPERATURE;

EID: 0037131487     PISSN: 09476539     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-3765(20021018)8:20<4796::AID-CHEM4796>3.0.CO;2-O     Document Type: Article

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