Expression of Ret receptor tyrosine kinase after transient forebrain ischemia is modulated by glial cell line-derived neurotrophic factor in rat hippocampus

Neuroscience Letters

Volumn 318, Issue 1, 2002, Pages 1-4

  Miyazaki, Hiroyuki ^a   Nagashima, Kazuo ^b   Okuma, Yasunobu ^a   Nomura, Yasuyuki ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Cerebral ischemia; GDNF family receptor; Glial cell line derived neurotrophic factor (GDNF); Hippocampus; Neuronal death; Ret

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA; RET RECEPTOR; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; CONTROLLED STUDY; FOREBRAIN; GLIA CELL; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MICROINJECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CELL DEATH; DROSOPHILA PROTEINS; GENE EXPRESSION; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTORS; HIPPOCAMPUS; ISCHEMIC ATTACK, TRANSIENT; MALE; MICROINJECTIONS; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEUROPROTECTIVE AGENTS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-RET; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR PROTEIN-TYROSINE KINASES; RNA, MESSENGER;

EID: 0037126981     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(01)02213-3     Document Type: Article

References (20)

1. Amelioration of brain edema by topical application of glial cell line-derived neurotrophic factor in reperfused rat brain
2. Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRα3-RET receptor complex
3. Up-regulation of GDNFR-α and c-ret mRNA in facial motor neurons following facial nerve injury in the rat
4. Signaling of the Ret receptor tyrosine kinase through the c-Jun NH2-terminal protein kinases (JNKs): Evidence for a divergence of the ERKs and JNKs pathways induced by Ret
5. GDNF signaling through the Ret receptor tyrosine kinase
6. c-Src is required for glial cell line-derived neurotrophic factor (GDNF) family ligand-mediated neuronal survival via a phosphatidylinositol-3 kinase (PI-3K)-dependent pathway
7. GDNF-induced activation of the Ret protein tyrosine kinase is mediated by GDNFR-α, a novel receptor for GDNF
8. A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor
9. Expression of glial cell line-derived neurotrophic factor induced by transient forebrain ischemia in rats
10. Glial cell line-derived neurotrophic factor protects against delayed neuronal death after transient forebrain ischemia in rats
11. Glial cell line-derived neurotrophic factor modulates ischemia-induced tyrosine hydroxylase expression in rat hippocampus
12. The messenger RNAs for both glial cell line-derived neurotrophic factor receptors, c-RET and GDNFRα are induced in the rat brain in response to kainate-induced excitation
13. Renal agenesis and the absence of enteric neurons in mice lacking GDNF
14. Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret
15. Complementary and overlapping expression of glial cell line-derived neurotrophic factor (GDNF), c-ret proto-oncogene, and actions in the adult rat CNS
16. Ret-dependent and -independent mechanisms of glial cell line-derived neurotrophic factor signaling in neuronal cells
17. Glial cell line-derived neurotrophic factor protects against ischemia-induced injury in the cerebral cortex
18. Glial cell line-derived neurotrophic factor signals through the RET receptor and activates mitogen-activated protein kinase
19. Expression of GDNF family receptor components during development: Implications in the mechanisms of interaction