Regulation of the anaphase-promoting complex/cyclosome by bimA(APC3) and proteolysis of NIMA

Molecular Biology of the Cell

Volumn 9, Issue 11, 1998, Pages 3019-3030

  Ye, Xiang S ^a,b   Fincher, Russell R ^a,c   Tang, Alice ^a   Osmani, Aysha H ^a   Osmani, Stephen A ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b ELI LILLY AND COMPANY   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE;

ANAPHASE; ARTICLE; ASPERGILLUS NIDULANS; ENZYME REGULATION; MITOSIS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ASPERGILLUS; EMERICELLA NIDULANS;

EID: 0031738641     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.9.11.3019     Document Type: Article

References (60)

1. Alfa, C.E., Ducommun, B., Beach, D., and Hyams, J.S. (1990). Distinct nuclear and spindle pole body populations of cyclin-cdc2 in fission yeast. Nature 347, 680-682.
2. Amon, A., Irniger, S., and Nasmyth, K. (1994). Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle. Cell 77, 1037-1050.
3. Brandeis, M., and Hunt, T. (1996). The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until onset of S phase. EMBO J. 15, 5280-5289.
4. Charles, J.F., Jaspersen, S.L., Tinker-Kulberg, R.L., Hwang, L., Szidon, A., and Morgan, D.O. (1998). The polo-related kinase cdc5 activates and is destroyed by the mitotic cyclin destruction machinery in S. cerevisiae. Curr. Biol. 8, 497-507.
5. Cohen-Fix, O., and Koshland, D. (1997). The metaphase-to-anaphase transition: avoiding a mid-life crisis. Curr. Opin. Cell Biol. 9, 800-806.
6. Cohen-Fix, O., Peters, J., Kirschner, M.W., and Koshland, D. (1996). Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p. Genes & Dev. 10, 3081-3093.
7. Descombes, P., and Nigg, E.A. (1998). The polo-like kinase P1x1 is required for M phase exit and destruction of mitotic regulators in Xenopus egg extracts. EMBO J. 17, 1328-1335.
8. Draetta, G., Luca, F., Westendorf, J., Brizuela, L., Ruderman, J., and Beach, D. (1990). Cdc2 protein kinase is complexed with both cyclin A and B: evidence for proteolytic inactivation of MPF. Cell 56, 829-838.
9. Engle, D.B., Osmani, S.A., Osmani, A.H., Rosborough, S., Xiang, X., and Morris, N.R. (1990). A negative regulator of mitosis in Aspergillus is a putative membrane-spanning protein. J. Biol. Chem. 265, 16132-16137.
10. Evans, T.E., Rosenthal, J., Youngbloom, K., Distel, K., and Hunt, T. (1983). Cyclin: a protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division. Cell 33, 389-396.
11. Funabiki, H., Yamano, H., Kumada, K., Hunt, T., and Yanagida, M. (1996). Cut2 proteolysis required for sister-chromatid separation in fission yeast. Nature 381, 438-441.
12. Gallant, P., and Nigg, E.A. (1992). Cyclin B2 undergoes cell cycle-dependent nuclear translocation and, when expressed as a non-destructible mutant, causes mitotic arrest in HeLa cells. J. Cell Biol. 117, 213-224.
13. Ghiara, J.B., Richardson, H.E., Sugimoto, K., Henze, M., Lew, D.J., Wittenberg, C., and Reed, S.I. (1991). A cyclin B homolog in S. cerevisiae: chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis. Cell 65, 163-174.
14. Glotzer, M., Murray, A.W., and Kirschner, M.W. (1991). Cyclin is degraded by the ubiquitin pathway. Nature 349, 132-138.
15. Grandin, N., and Reed, S.I. (1993). Differential function and expression of Saccharomyces cerevisiae B-type cyclins in mitosis and meiosis. Mol. Cell. Biol. 13, 2113-2125.
16. He, X., Patterson, T.E., and Sazer, S. (1997). The Schizosaccharomyces pombe spindle checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complex. Proc. Natl. Acad. Sci. USA 94, 7965-7970.
17. Hershko, A. (1997). Roles of ubiquitin-medicated proteolysis in cell cycle control. Curr. Opin. Cell Biol. 9, 788-800.
18. Hershko, A., Ganoth, D., Sudakin, V., Dahan, A., Cohen, L.H., Luca, F.C., and Ruderman, J. (1994). Components of a system that ligates cyclin to ubiquitin and their regulation by protein kinase cdc2. J. Biol. Chem. 269, 4940-4946.
19. Hirano, T., Hiraoka, Y., and Yanagida, M. (1990). A temperature sensitive mutation of the S. pombe gene nuc2+ that encodes a nuclear-scaffold protein blocks spindle elongation in mitotic anaphase. J. Cell Biol. 106, 307-317.
20. Hirano, T., Kinoshita, N., Morikawa, K., and Yanagida, M. (1994). Snap helix with a knob and hole essential repeats on S. pombe nuclear protein nuc2+. Cell 60, 319-328.
21. Hunt, T., Luca, F.C., and Ruderman, J.V. (1992). The requirements for protein synthesis and degradation, and the control of destruction of cyclins A and B in the meiotic and mitotic cell cycles of the clam embryo. J. Cell Biol. 116, 707-724.
22. James, S., Mirabito, P., Scacheri, P., and Morris, N. (1995). The Aspergillus nidulans bimE (blocked-in-mitosis) gene encodes multiple cell cycle functions involved in mitotic checkpoint control and mitosis. J. Cell Sci. 108, 3485-3499.
23. Juang, Y.L., Huang, J., Peters, J.M., McLaughlin, M.E., Tai, C.Y., and Pellman, D. (1997). APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle. Science 275, 1311-1314.
24. King, R.W., Deshaies, R.J., Peters, J.M., and Kirschner, M.W. (1996a). How proteolysis drives the cell cycle. Science 274, 1652-1659.
25. King, R.W., Glotzer, M., and Kirschner, M.W. (1996b). Mutagenic analysis of the destruction signal of mitotic cyclins and the structural characterization of ubiquitinated intermediates. Mol. Biol. Cell 7, 1343-1357.
26. King, R.W., Peters, J.M., Tugendreich, S., Rolfe, M., Hieter, P., and Kirschner, M.W. (1995). A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B. Cell 81, 279-288.
27. Lahav-Baratz, S., Sudakin, V., Ruderman, J.V., and Hershko, A. (1995). Reversible phosphorylation controls the activity of cyclosome-associated cyclin-ubiquitin ligase. Proc. Natl. Acad. Sci. USA 92, 9303-9307.
28. Lamb, J.R., Michaud, W.A., Sikorski, R.S., and Mieter, P.A. (1994). Cdc16p, Cdc23p and Cdc27p form a complex essential for mitosis. EMBO J. 13, 4321-4328.
29. Li, Y., Gorbea, C., Mahaffey, D., Rechsteiner, M., and Benezra, R. (1997). MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity. Proc. Natl. Acad. Sci. USA 94, 12431-12436.
30. APC3, a component of the Aspergillus anaphase promoting complex/cyclosome, is required for a G2 checkpoint blocking entry into mitosis in the absence of NIMA function. J. Cell Sci. 111, 1453-1465.
31. Luca, F.C., Shibuya, E.K., Dohrmann, C.E., and Ruderman, J.V. (1991). Both cyclin A Δ60 and B Δ97 are stable and arrest cells in M-phase, but only cyclin B Δ97 turns on cyclin destruction. EMBO J. 20, 4311-4320.
32. Michaelis, C., Ciosk, R., and Nasmyth, K. (1997). Cohesins:chromosomal proteins that prevent premature separation of sister chromatids. Cell 91, 35-45.
33. Mirabito, P.M., and Morris, N.R. (1993). BIMA, a TPR-containing protein required for mitosis, localizes to the spindle pole body in Aspergillus nidulans. J. Cell Biol. 120, 959-968.
34. Morris, N.R. (1976). Mitotic mutants of Aspergillus nidulans. Genet. Res. 26, 237-254.
35. Murray, A. (1995). Cyclin ubiquitination: the destructive and of mitosis. Cell 81, 149-152.
36. Murray, A.W., Solomon, M.J., and Kirschner, M.W. (1989). The role of cyclin synthesis and degradation in the control of maturation promoting factor activity. Nature 339, 280-286.
37. O'Connell, M.J., Norbury, C., and Nurse, P. (1994). Premature chromatin condensation upon accumulation of NIMA. EMBO J. 13, 4926-4937.
38. O'Donnell, K.L., Osmani, A.M., Osmani, S.A., and Morris, N.R. (1991). bimA encodes a member of the tetratricopeptide repeat family of proteins and is required for the completion of mitosis in Aspergillus nidulans. J. Cell Sci. 99, 711-719.
39. Oakley, B.R., and Osmani, S.A. (1993). Cell-cycle analysis using the filamentous fungus Aspergillus nidulans. In: The Cell Cycle, a Practical Approach, ed. P. Fantes and R. Brooks, Oxford, United Kingdom: IRL Press, 127-142.
40. Osmani, A.M., McGuire, S.L., and Osmani, S.A. (1991a). Parallel activation of the NIMA and p34cdc2 cell cycle-regulated protein kinases is required to initiate mitosis in A. nidulans. Cell 67, 283-291.
41. Osmani, A.M., O'Donnell, K., Pu, R.T., and Osmani, S.A. (1991b). Activation of the nimA protein kinase plays a unique role during mitosis that cannot be bypassed by absence of the bimE checkpoint. EMBO J. 10, 2669-2679.
42. Osmani, S.A., Engle, D.B., Doonan, J.H., and Morris, N.R. (1988). Spindle formation and chromatin condensation in cells blocked at interphase by mutation of a negative cell cycle control gene. Cell 52, 241-251.
43. Osmani, S.A., and Ye, X.S. (1996). Cell cycle regulation in Aspergillus by two protein kinases. Biochem. J. 317, 633-641.
44. Peters, J., King, R.W., Hoog, C., and Kirschner, M.W. (1996). Identification of BIME as a subunit of the anaphase-promoting complex. Science 274, 1199-1201.
45. Pu, R.T., and Osmani, S.A. (1995). Mitotic destruction of the cell cycle regulated NIMA protein kinase of Aspergillus nidulans is required for mitotic exit. EMBO J. 14, 995-1003.
46. Richardson, H., Lew, D.J., Henze, M., Sugimoto, K., and Reed, S.I. (1992). Cyclin-B homologs in Saccharomyces cerevisiae function in S phase and in G2. Genes & Dev. 6, 2021-2034.
47. Shirayama, M., Zachariae, W., Ciosk, R., and Nasmyth, K. (1998), The polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/ fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae. EMBO J. 17, 1349.
48. Sikorski, R.S., Boguski, M.S., Goebl, M., and Hieter, P. (1990). A repeating amino acid motif in CDC23 defines a family of proteins and a new relationship among genes required for mitosis and RNA synthesis. Cell 60, 307-317.
49. Starborg, M., Brundell, E., Gell, K., and Hoog, C. (1994). A novel murine gene encoding a 216-kDa protein is related to a mitotic checkpoint regulator previously identified in Aspergillus nidulans. J. Biol. Chem. 269, 24133-24137.
50. Sudakin, V., Ganoth, D., Dahan, A., Heller, H., Hershko, J., Luca, F.C., Ruderman, J.V., and Hershko, A. (1995). The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis. Mol. Biol. Cell 6, 185-198.
51. Surana, U., Amon, A., Dowzer, C., McGrew, J., Byers, B., and Nasmyth, K. (1993). Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast. EMBO J. 12, 1969-1978.
52. Townsley, F.M., and Ruderman, J.V. (1998). Proteolytic ratchets that control progression through mitosis. Trends Cell Biol. 8, 238-244.
53. Tugendreich, S., Tomkiel, J., Earnshaw, W., and Hieter, P. (1995). CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition. Cell 81, 261-268.
54. Yamano, H., Gannon, J., and Hunt, T. (1996). The role of proteolysis in cell cycle progression in Schizosaccharomyces pombe. EMBO J. 15, 5268-5279.
55. cdc2. J. Biol. Chem. 272, 33384-33393.
56. cdc2, inhibit NIMA and prevent premature mitosis. EMBO J. 15, 3599-3610.
57. cdc2 in Aspergillus nidulans. EMBO J. 25, 101-112.
58. cdc2/cyclin B: coordination of two mitosis promoting kinases. EMBO J. 14, 986-994.
59. Zachariae, W., and Nasmyth, K. (1996). TPR proteins required for anaphase progression mediate ubiquitination of mitotic B-type cyclins in yeast. Mol. Biol. Cell 7, 791-801.
60. Zachariae, W., Shin, T.H., Galova, M., Obermaier, B., and Nasmyth, K. (1996). Identification of subunits of the anaphase-promoting complex of Saccharomyces cerevisiae. Science 274, 1201-1204.