Solution- and solid-phase asymmetric synthesis of substituted N-hydroxypyrrolidine dicarboxylic acids

Tetrahedron Letters

Volumn 43, Issue 51, 2002, Pages 9441-9444

  Hanessian, Stephen ^a   Bayrakdarian, Malken ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Amino acid; Cycloaddition; N hydroxylactone; Nitrone

Indexed keywords

ALDEHYDE DERIVATIVE; DICARBOXYLIC ACID DERIVATIVE; NITRONE; PROLINE DERIVATIVE; PYRROLIDINE DERIVATIVE;

ARTICLE; CRYSTAL STRUCTURE; CYCLOADDITION; DIASTEREOISOMER; DRUG OXIDATION; DRUG SYNTHESIS; POLYMERIZATION; SOLID; STEREOCHEMISTRY;

EID: 0037121613     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(02)02288-8     Document Type: Article

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49. 4), filtered and evaporated to dryness. The resulting residue was purified by flash chromatography (EtOAc/hexanes, 1:1) to give the desired bicyclic N-hydroxypyrrolidine lactone as a colorless oil.