-
1
-
-
0028147361
-
Programmed cell death (apoptosis) and response to anti-cancer drugs
-
Smets L.A. Programmed cell death (apoptosis) and response to anti-cancer drugs. Anti-Cancer Drugs. 5:1994;3-9.
-
(1994)
Anti-Cancer Drugs
, vol.5
, pp. 3-9
-
-
Smets, L.A.1
-
3
-
-
0030999750
-
Apoptosis and the dilemma of cancer chemotherapy
-
Hannun Y.A. Apoptosis and the dilemma of cancer chemotherapy. Blood. 89:1997;1845-1853.
-
(1997)
Blood
, vol.89
, pp. 1845-1853
-
-
Hannun, Y.A.1
-
4
-
-
0034654326
-
Activation of apoptosis pathways by anticancer treatment
-
Debatin K.M. Activation of apoptosis pathways by anticancer treatment. Toxicol. Lett. 112-113:2000;41-48.
-
(2000)
Toxicol. Lett.
, vol.112-113
, pp. 41-48
-
-
Debatin, K.M.1
-
6
-
-
0034630167
-
Induction of apoptosis by cancer chemotherapy
-
Kaufmann S.H., Earnshaw W.C. Induction of apoptosis by cancer chemotherapy. Exp. Cell Res. 256:2000;42-49.
-
(2000)
Exp. Cell Res.
, vol.256
, pp. 42-49
-
-
Kaufmann, S.H.1
Earnshaw, W.C.2
-
7
-
-
0026515757
-
Quinone chemistry and toxicity
-
Monks T.J., Hanzlik R.P., Cohen G.M., Ross D., Graham D.G. Quinone chemistry and toxicity. Toxicol. Appl. Pharmacol. 112:1992;2-16.
-
(1992)
Toxicol. Appl. Pharmacol.
, vol.112
, pp. 2-16
-
-
Monks, T.J.1
Hanzlik, R.P.2
Cohen, G.M.3
Ross, D.4
Graham, D.G.5
-
8
-
-
0001885549
-
Anthracyclines
-
B.A. Chabner, & J.M. Collins. Philadelphia, PA: Lippincott
-
Myers C.E., Chabner B.A. Anthracyclines. Chabner B.A., Collins J.M., Cancer Chemotherapy: Principles and Practice. 1990;356-381 Lippincott, Philadelphia, PA.
-
(1990)
Cancer Chemotherapy: Principles and Practice
, pp. 356-381
-
-
Myers, C.E.1
Chabner, B.A.2
-
10
-
-
0023885890
-
Characterization of L5178Y murine lymphoblasts resistant to quinone antitumor agents
-
Begleiter A., Leith M.K., McClarty G., Beenken S., Goldenberg G.J., Wright J.A. Characterization of L5178Y murine lymphoblasts resistant to quinone antitumor agents. Cancer Res. 48:1988;1727-1735.
-
(1988)
Cancer Res.
, vol.48
, pp. 1727-1735
-
-
Begleiter, A.1
Leith, M.K.2
McClarty, G.3
Beenken, S.4
Goldenberg, G.J.5
Wright, J.A.6
-
12
-
-
0024316466
-
DNA topoisomerase poisons as antitumor drugs
-
Liu L.F. DNA topoisomerase poisons as antitumor drugs. Annu. Rev. Biochem. 58:1989;351-375.
-
(1989)
Annu. Rev. Biochem.
, vol.58
, pp. 351-375
-
-
Liu, L.F.1
-
13
-
-
0021807522
-
Adriamycin-enhanced membrane lipid peroxidation in isolated rat nuclei
-
Mimnaugh E.G., Kennedy K.A., Trush M.A., Sinha B.K. Adriamycin-enhanced membrane lipid peroxidation in isolated rat nuclei. Cancer Res. 45:1985;3296-3304.
-
(1985)
Cancer Res.
, vol.45
, pp. 3296-3304
-
-
Mimnaugh, E.G.1
Kennedy, K.A.2
Trush, M.A.3
Sinha, B.K.4
-
14
-
-
0025090826
-
Modulation of doxorubicin-induced chromosomal damage by calmodulin inhibitors and its relationship to cytotoxicity in progressively doxorubicin-resistant tumor cells
-
Ganapathi R., Grabowski D., Hoeltge G., Neelon R. Modulation of doxorubicin-induced chromosomal damage by calmodulin inhibitors and its relationship to cytotoxicity in progressively doxorubicin-resistant tumor cells. Biochem. Pharmacol. 40:1990;1657-1662.
-
(1990)
Biochem. Pharmacol.
, vol.40
, pp. 1657-1662
-
-
Ganapathi, R.1
Grabowski, D.2
Hoeltge, G.3
Neelon, R.4
-
15
-
-
0027278808
-
Apoptosis induced by anthracycline antibiotics in P388 parent and multidrug-resistant cells
-
Ling Y.H., Priebe W., Perez-Soler R. Apoptosis induced by anthracycline antibiotics in P388 parent and multidrug-resistant cells. Cancer Res. 53:1993;1845-1852.
-
(1993)
Cancer Res.
, vol.53
, pp. 1845-1852
-
-
Ling, Y.H.1
Priebe, W.2
Perez-Soler, R.3
-
16
-
-
0030775164
-
Bcl-2 and mdr-1 gene expression during doxorubicin-induced apoptosis in murine leukemic P388 and P388/R84 cells
-
Ramachandran C., You W., Krishan A. Bcl-2 and mdr-1 gene expression during doxorubicin-induced apoptosis in murine leukemic P388 and P388/R84 cells. Anticancer Res. 17:1997;3369-3376.
-
(1997)
Anticancer Res.
, vol.17
, pp. 3369-3376
-
-
Ramachandran, C.1
You, W.2
Krishan, A.3
-
17
-
-
0027237540
-
Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumour cells
-
Skladanowski A., Konopa J. Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumour cells. Biochem. Pharmacol. 46:1993;375-382.
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 375-382
-
-
Skladanowski, A.1
Konopa, J.2
-
18
-
-
0033021072
-
Dual mechanism of daunorubicin-induced cell death in both sensitive and MDR-resistant HL-60 cells
-
Côme M.G., Skladanowski A., Larsen A.K., Laurent G. Dual mechanism of daunorubicin-induced cell death in both sensitive and MDR-resistant HL-60 cells. Br. J. Cancer. 79:1999;1090-1097.
-
(1999)
Br. J. Cancer
, vol.79
, pp. 1090-1097
-
-
Côme, M.G.1
Skladanowski, A.2
Larsen, A.K.3
Laurent, G.4
-
19
-
-
0035954243
-
Induction of apoptosis in MDR1 expressing cells by daunorubicin with combinations of suboptimal concentrations of P-glycoprotein modulators
-
Aszalos A., Ladányi A., Bocsi J., Szende B. Induction of apoptosis in MDR1 expressing cells by daunorubicin with combinations of suboptimal concentrations of P-glycoprotein modulators. Cancer Lett. 167:2001;157-162.
-
(2001)
Cancer Lett.
, vol.167
, pp. 157-162
-
-
Aszalos, A.1
Ladányi, A.2
Bocsi, J.3
Szende, B.4
-
20
-
-
0030781018
-
Doxorubicin-induced apoptosis in human T-cell leukemia is mediated by caspase-3 activation in a Fas-independent way
-
Gamen S., Anel A., Lasierra P., Alava M.A., Martinez-Lorenzo M.J., Piñeiro A., Naval J. Doxorubicin-induced apoptosis in human T-cell leukemia is mediated by caspase-3 activation in a Fas-independent way. FEBS Lett. 417:1997;360-364.
-
(1997)
FEBS Lett.
, vol.417
, pp. 360-364
-
-
Gamen, S.1
Anel, A.2
Lasierra, P.3
Alava, M.A.4
Martinez-Lorenzo, M.J.5
Piñeiro, A.6
Naval, J.7
-
21
-
-
0000146455
-
Triptycenes: A novel synthetic class of bifunctional anticancer drugs that inhibit nucleoside transport, induce DNA cleavage and decrease the viability of leukemic cells in the nanomolar range in vitro
-
Perchellet E.M., Magill M.J., Huang X., Brantis C.E., Hua D.H., Perchellet J.P. Triptycenes: a novel synthetic class of bifunctional anticancer drugs that inhibit nucleoside transport, induce DNA cleavage and decrease the viability of leukemic cells in the nanomolar range in vitro. Anti-Cancer Drugs. 10:1999;749-766.
-
(1999)
Anti-Cancer Drugs
, vol.10
, pp. 749-766
-
-
Perchellet, E.M.1
Magill, M.J.2
Huang, X.3
Brantis, C.E.4
Hua, D.H.5
Perchellet, J.P.6
-
22
-
-
0036021016
-
Among substituted 9,10-dihydro-9,10-[1,2]benzenoanthracene-1,4,5,8-tetraones, the lead antitumor triptycene bisquinone TT24 blocks nucleoside transport, induces apoptotic DNA fragmentation and decreases the viability of L1210 leukemic cells in the nanomolar range of daunorubicin in vitro
-
in press
-
Perchellet E.M., Sperfslage B.J., Wang Y., Huang X., Tamura M., Hua D.H., Perchellet J.P. Among substituted 9,10-dihydro-9,10-[1,2]benzenoanthracene-1,4,5,8-tetraones, the lead antitumor triptycene bisquinone TT24 blocks nucleoside transport, induces apoptotic DNA fragmentation and decreases the viability of L1210 leukemic cells in the nanomolar range of daunorubicin in vitro. Anti-Cancer Drugs. 13:2002;. in press.
-
(2002)
Anti-Cancer Drugs
, vol.13
-
-
Perchellet, E.M.1
Sperfslage, B.J.2
Wang, Y.3
Huang, X.4
Tamura, M.5
Hua, D.H.6
Perchellet, J.P.7
-
23
-
-
0035656150
-
A synthetic triptycene bisquinone, which blocks nucleoside transport and induces DNA fragmentation, retains its cytotoxic efficacy in daunorubicin-resistant HL-60 cell lines
-
Wang B., Wu M., Perchellet E.M., McIlvain C.J., Sperfslage B.J., Huang X., Tamura M., Stephany H.A., Hua D.H., Perchellet J.P. A synthetic triptycene bisquinone, which blocks nucleoside transport and induces DNA fragmentation, retains its cytotoxic efficacy in daunorubicin-resistant HL-60 cell lines. Int. J. Oncol. 19:2001;1169-1178.
-
(2001)
Int. J. Oncol.
, vol.19
, pp. 1169-1178
-
-
Wang, B.1
Wu, M.2
Perchellet, E.M.3
McIlvain, C.J.4
Sperfslage, B.J.5
Huang, X.6
Tamura, M.7
Stephany, H.A.8
Hua, D.H.9
Perchellet, J.P.10
-
24
-
-
0034630317
-
Apoptotic DNA fragmentation
-
Nagata S. Apoptotic DNA fragmentation. Exp. Cell Res. 256:2000;12-18.
-
(2000)
Exp. Cell Res.
, vol.256
, pp. 12-18
-
-
Nagata, S.1
-
25
-
-
0031298259
-
Cleavage of poly(ADP-ribose) polymerase: A sensitive parameter to study cell death
-
Duriez P.J., Shah G.M. Cleavage of poly(ADP-ribose) polymerase: a sensitive parameter to study cell death. Biochem. Cell Biol. 75:1997;337-349.
-
(1997)
Biochem. Cell Biol.
, vol.75
, pp. 337-349
-
-
Duriez, P.J.1
Shah, G.M.2
-
26
-
-
0035796025
-
Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death
-
Herceg Z., Wang Z.Q. Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death. Mutat. Res. 477:2001;97-110.
-
(2001)
Mutat. Res.
, vol.477
, pp. 97-110
-
-
Herceg, Z.1
Wang, Z.Q.2
-
27
-
-
0035835481
-
Poly(APD-ribosyl)ation, a DNA damage-driven protein modification and regulator of genomic instability
-
Bürkle A. Poly(APD-ribosyl)ation, a DNA damage-driven protein modification and regulator of genomic instability. Cancer Lett. 163:2001;1-5.
-
(2001)
Cancer Lett.
, vol.163
, pp. 1-5
-
-
Bürkle, A.1
-
28
-
-
0027255417
-
Specific proteolytic cleavage of poly(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis
-
Kaufmann S.H., Desnoyers S., Ottaviano Y., Davidson N.E., Poirier G.G. Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. Cancer Res. 53:1993;3976-3985.
-
(1993)
Cancer Res.
, vol.53
, pp. 3976-3985
-
-
Kaufmann, S.H.1
Desnoyers, S.2
Ottaviano, Y.3
Davidson, N.E.4
Poirier, G.G.5
-
29
-
-
0029068871
-
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
-
Nicholson D.W., Ali A., Thornberry N.A., Vaillancourt J.P., Ding C.K., Gallant M., Gareau Y., Griffin P.R., Labelle M., Lazebnik Y.A., Munday N.A., Raju S.M., Smulson M.E., Yamin T.T., Yu V.L., Miller D.K. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature. 376:1995;37-43.
-
(1995)
Nature
, vol.376
, pp. 37-43
-
-
Nicholson, D.W.1
Ali, A.2
Thornberry, N.A.3
Vaillancourt, J.P.4
Ding, C.K.5
Gallant, M.6
Gareau, Y.7
Griffin, P.R.8
Labelle, M.9
Lazebnik, Y.A.10
Munday, N.A.11
Raju, S.M.12
Smulson, M.E.13
Yamin, T.T.14
Yu, V.L.15
Miller, D.K.16
-
30
-
-
0028990125
-
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
-
Tewari M., Quan L.T., O'Rourke K., Desnoyers S., Zeng Z., Beidler D.R., Poirier G.G., Salvesen G.S., Dixit V.M. Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell. 81:1995;801-809.
-
(1995)
Cell
, vol.81
, pp. 801-809
-
-
Tewari, M.1
Quan, L.T.2
O'Rourke, K.3
Desnoyers, S.4
Zeng, Z.5
Beidler, D.R.6
Poirier, G.G.7
Salvesen, G.S.8
Dixit, V.M.9
-
31
-
-
0037012889
-
Syntheses and bioactivities of substituted 9,10-dihydro-9,10-{1,2}benzenoanthracene-1,4,5,8-tetraones. Unusual reactivities with amines
-
Hua D.H., Tamura M., Huang X., Stephany H.A., Helfrich B.A., Perchellet E.M., Sperfslage B.J., Perchellet J.P., Jiang S., Kyle D.E., Chiang P.K. Syntheses and bioactivities of substituted 9,10-dihydro-9,10-{1,2}benzenoanthracene-1,4,5,8-tetraones. Unusual reactivities with amines. J. Org. Chem. 67:2002;2907-2912.
-
(2002)
J. Org. Chem.
, vol.67
, pp. 2907-2912
-
-
Hua, D.H.1
Tamura, M.2
Huang, X.3
Stephany, H.A.4
Helfrich, B.A.5
Perchellet, E.M.6
Sperfslage, B.J.7
Perchellet, J.P.8
Jiang, S.9
Kyle, D.E.10
Chiang, P.K.11
-
32
-
-
0025267059
-
Mechanisms of multidrug resistance in HL60 cells: Detection of resistance-associated proteins with antibodies against synthetic peptides that correspond to the deduced sequence of P-glycoprotein
-
Marquardt D., McCrone S., Center M.S. Mechanisms of multidrug resistance in HL60 cells: detection of resistance-associated proteins with antibodies against synthetic peptides that correspond to the deduced sequence of P-glycoprotein. Cancer Res. 50:1990;1426-1430.
-
(1990)
Cancer Res.
, vol.50
, pp. 1426-1430
-
-
Marquardt, D.1
McCrone, S.2
Center, M.S.3
-
33
-
-
0030001378
-
P-Glycoproteins and multidrug resistance
-
Bellamy W.T. P-Glycoproteins and multidrug resistance. Annu. Rev. Pharmacol. Toxicol. 36:1996;161-183.
-
(1996)
Annu. Rev. Pharmacol. Toxicol.
, vol.36
, pp. 161-183
-
-
Bellamy, W.T.1
-
34
-
-
0029821995
-
Multidrug resistance mediated by the multidrug resistance protein (MRP) gene
-
Lautier D., Canitrot Y., Deeley R.G., Cole S.P.C. Multidrug resistance mediated by the multidrug resistance protein (MRP) gene. Biochem. Pharmacol. 52:1996;967-977.
-
(1996)
Biochem. Pharmacol.
, vol.52
, pp. 967-977
-
-
Lautier, D.1
Canitrot, Y.2
Deeley, R.G.3
Cole, S.P.C.4
-
35
-
-
0027249710
-
The MRP gene associated with a non-P-glycoprotein multidrug resistance encodes a 190-kDa membrane bound glycoprotein
-
Krishnamachary N., Center M.S. The MRP gene associated with a non-P-glycoprotein multidrug resistance encodes a 190-kDa membrane bound glycoprotein. Cancer Res. 53:1993;3658-3661.
-
(1993)
Cancer Res.
, vol.53
, pp. 3658-3661
-
-
Krishnamachary, N.1
Center, M.S.2
-
36
-
-
0028102478
-
Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE
-
Lazebnik Y.A., Kaufmann S.H., Desnoyers S., Poirier G.G., Earnshaw W.C. Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature. 371:1994;346-347.
-
(1994)
Nature
, vol.371
, pp. 346-347
-
-
Lazebnik, Y.A.1
Kaufmann, S.H.2
Desnoyers, S.3
Poirier, G.G.4
Earnshaw, W.C.5
-
37
-
-
0030777366
-
Activation of CPP32-like proteases is not sufficient to trigger apoptosis: Inhibition of apoptosis by agents that suppress activation of AP24, but not CPP32-like activity
-
Wright S.C., Schellenberger U., Wang H., Kinder D.H., Talhouk J.W., Larrick J.W. Activation of CPP32-like proteases is not sufficient to trigger apoptosis: inhibition of apoptosis by agents that suppress activation of AP24, but not CPP32-like activity. J. Exp. Med. 186:1997;1107-1117.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1107-1117
-
-
Wright, S.C.1
Schellenberger, U.2
Wang, H.3
Kinder, D.H.4
Talhouk, J.W.5
Larrick, J.W.6
-
38
-
-
0031727477
-
Involvement of both caspase-like proteases and serine proteases in apoptotic cell death induced by ricin, modeccin, diphtheria toxin, and pseudomonas toxin
-
Komatsu N., Oda T., Muramatsu T. Involvement of both caspase-like proteases and serine proteases in apoptotic cell death induced by ricin, modeccin, diphtheria toxin, and pseudomonas toxin. J. Biochem. 124:1998;1038-1044.
-
(1998)
J. Biochem.
, vol.124
, pp. 1038-1044
-
-
Komatsu, N.1
Oda, T.2
Muramatsu, T.3
-
39
-
-
0030187244
-
Proteolytic cleavage during chemotherapy-induced apoptosis
-
Kaufmann S.H. Proteolytic cleavage during chemotherapy-induced apoptosis. Mol. Med. Today. 2:1996;298-303.
-
(1996)
Mol. Med. Today
, vol.2
, pp. 298-303
-
-
Kaufmann, S.H.1
-
40
-
-
0033280669
-
Biochemical pathways of caspase activation during apoptosis
-
Budihardjo I., Oliver H., Lutter M., Luo X., Wang X. Biochemical pathways of caspase activation during apoptosis. Annu. Rev. Cell Dev. Biol. 15:1999;269-290.
-
(1999)
Annu. Rev. Cell Dev. Biol.
, vol.15
, pp. 269-290
-
-
Budihardjo, I.1
Oliver, H.2
Lutter, M.3
Luo, X.4
Wang, X.5
|