The factor H protein family

Immunopharmacology

Volumn 42, Issue 1-3, 1999, Pages 53-60

  Zipfel, Peter F ^a   Jokiranta, T Sakari ^b   Hellwage, Jens ^a   Koistinen, Vesa ^b   Meri, Seppo ^b  

^a BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

C3 convertase; Factor H; Factor H related proteins

Indexed keywords

BACTERIAL PROTEIN; CLASSICAL COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT COMPONENT C3; COMPLEMENT FACTOR H; GLYCOSAMINOGLYCAN; HEPARIN; INTEGRIN RECEPTOR; M PROTEIN;

AMINO TERMINAL SEQUENCE; BINDING SITE; CELL SPREADING; CONFERENCE PAPER; HUMAN; MULTIGENE FAMILY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; RECEPTOR BINDING;

COMPLEMENT FACTOR H; HUMANS; MULTIGENE FAMILY;

EID: 0033029745     PISSN: 01623109     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0162-3109(99)00015-6     Document Type: Conference Paper

References (31)

1. Blackmore T.K., Sadlon T.A., Ward H.M., Lublin D.M., Gordon D.L. Identification of a heparin binding domain in the seventh short consensus repeat of complement factor H. J. Immunol. 157:1996;5422-5427.
2. Blackmore T.K., Hellwage J., Sadlon T.A., Higgs N., Zipfel P.F., Ward H.M., Gordon D.L. Identification of the second heparin-binding domain in human complement factor H. J. Immunol. 160:1998;3342-3348.
3. Diaz-Guillen, A., Rodriguez de Cordoba, S., Heine-Suner, D., 1998. A radiation hybrid map of complement factor H and factor H-related genes. Immunogenetics, in press.
4. DiScipio R., Daffern P.J., Schraufstätter I.U., Sriramarao P. Human polymorphonuclear leukocytes adhere to complement factor H through an interaction that involves αmβ2 (CD11b/CD18). J. Immunol. 160:1998;4057-4066.
5. Estaller C., Koistinen V., Schwaeble W., Dierich M.P., Weiss E.H. Cloning of the 1.4-kb mRNA species of human complement factor H reveals a novel member of the short consensus repeat family related to the carboxy terminal of the classical 150-kDa molecule. J. Immunol. 146:1991;3190-3196.
6. Heine-Suner D., Diaz-Guillen A., Sanchez-Corral P., Rodriguez de Cordoba S. An integrated map of the human RCA gene cluster that positions 85 genes and polymorphic markers. Mol. Immunol. 35:1998;395. abstract.
7. Hellwage J., Kühn S., Zipfel P.F. The human complement regulatory factor H-like protein 1, which represents a truncated form of factor H displays cell spreading activity. Biochem. J. 326:1997;321-327.
8. Hellwage J., Jokiranta T.S., Koistinen V., Zipfel P.F., Meri S. Interaction of factor H-related proteins with FHR-3 and FHR-4 with the third component of complement. Mol. Immunol. 35:1998;358. abstract.
9. Horstmann R.D., Sievertsen H.J., Knobloch J., Fischetti V.A. Antiphagocytic activity of streptococcal M protein: selective binding of complement control protein factor H. Proc. Natl. Acad. Sci. USA. 85:1988;1657-1661.
10. Johnsson E., Berggard K., Kotarski H., Hellwage J., Zipfel P.F., Sjöbring U., Lindahl G. Molecular mechanisms of immune evasion: binding of the human complement regulator FHL-1 to M proteins confers resistance of streptococci to alternative complement. J. Immunol. 160:1998;4894-4901.
11. Jokiranta T.S., Zipfel P.F., Hakulinen J., Kühn S., Panburn M.K., Tamerius J.D., Meri S. Analysis of the recognition mechanism of the alternative pathway of complement by monoclonal anti-factor H antibodies: evidence for multiple interactions between H and surface bound C3b. FEBS Lett. 393:1996;297-302.
12. Jokiranta T.S., Hellwage J., Koistinen V., Zipfel P.F., Meri S. Each of the three binding sites of factor H interacts with a distinct site on C3b. Mol. Immunol. 35:1998;360. abstract.
13. Koistinen V. Effect of complement-protein-C3b density on the binding of complement factor H to surface bound C3b. Biochem. J. 280:1991;255-259.
14. Kotarsky H., Hellwage J., Johnsson E., Skerka C., Svensson H.G., Lindahl G., Sjöbring U., Zipfel P.F. Identification of a domain in human factor H and factor H-like protein-1 required for the interaction with streptococcal M proteins. J. Immunol. 160:1998;3349-3354.
15. iF-globulin from human serum and its characterization as the fifth component of complement. J. Exp. Med. 122:1965;277-298.
16. 1H for cleavage of C3b and C4b in solution. J. Exp. Med. 146:1977;257-270.
17. Pangburn M.K., Atkinson M.A.L., Meri S. Localization of the heparin-binding site on complement factor H. J. Biol. Chem. 266:1993;16847-16853.
18. Park C.T., Wright S.D. Plasma lipopolysaccharide-binding protein is found associated with a particle containing apolipoprotein A-I, phospholipid, and factor H-related proteins. J. Biol. Chem. 271:1996;18054-18060.
19. Ram S., Sharma A.K., Simpson S.D., Gulati S., McQuillen D.P., Pangburn M.K., Rice P.A. A novel sialic acid binding site on factor H mediates serum resistance of sialylated Neisseria gonorrhoeae. J. Exp. Med. 187:1998;743-752.
20. Ram S., McQuillen D.P., Gulati S., Elkins C., Pangburn M.K., Rice P.A. Binding of complement factor H to loop 5 of porin protein 1A: a molecular mechanism of serum resistance of nonsialylated Neisseria gonorrhoeae. J. Exp. Med. 188:1998;671-680.
21. Sim R.B., Kölble K., McAleer M.A., Dominguez O., Dee V.M. Genetics and deficiencies of the soluble regulatory proteins of the complement system. Int. Rev. Immunol. 10:1993;63-86.
22. Sharma A.K., Pangburn M.K. Identification of three physically and functionally distinct binding sites for C3b in human complement factor H by deletion mutagenesis. Proc. Natl. Acad. Sci. USA. 93:1996;10996-11001.
23. Skerka C., Horstmann R.D., Zipfel P.F. Molecular cloning of a human serum protein structurally related to complement factor H. J. Biol. Chem. 266:1991;12015-12020.
24. Skerka C., Timmann C., Horstmann R.D., Zipfel P.F.- Two additional human serum proteins structurally related to complement factor H. Evidence for a family of factor H-related genes. J. Immunol. 148:1992;3313-3318.
25. Skerka C., Kühn S., Günther K., Lingelbach K., Zipfel P.F. A novel short consensus repeat-containing molecule is related to human complement factor H. J. Biol. Chem. 268:1993;2904-2908.
26. Skerka C., Moulds J.A., Taillon-Miller P., Hourcade D., Zipfel P.F. The human factor H-related gene 2 (FHR2): gene structure and linkage to the coagulation factor XIIIb gene. Immunogenetics. 42:1995;268-274.
27. Skerka C., Hellwage J., Weber W., Tilkorn A., Buck F., Marti T., Kampen E., Beisiegel U., Zipfel P.F. The human factor H-related protein 4 (FHR-4). A novel short consensus repeat-containing protein is associated with human triglyceride-rich lipoproteins. J. Biol. Chem. 272:1997;5627-5634.
28. Vik D.P., Munoz-Canovez P., Chaplin D.D., Tack B.F. Factor H. Curr. Topics Microbiol. Immunol. 153:1989;147-162.
29. 1H globulin. J. Exp. Med. 144:1976;1147.
30. Zipfel P.F., Skerka C. Complement factor H and related proteins: an expanding family of complement-regulatory proteins? Immunol. Today. 15:1994;121-126.
31. Zipfel P.F., Skerka C. The human factor H-like protein 1: a complement regulatory protein with cell adhesion function. Immunol. Today. 20:1999;135-140.