Antigen-nonspecific recruitment of Th2 cells to the lung as a mechanism for viral infection-induced allergic asthma

Journal of Immunology

Volumn 169, Issue 10, 2002, Pages 5458-5467

  Stephens, Robin ^a   Randolph, David A ^a   Huang, Guangming ^a   Holtzman, Michael J ^a   Chaplin, David D ^a  

^a University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; INTERLEUKIN 5; LYSOZYME; OVALBUMIN;

ADOPTIVE TRANSFER; ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTING CELL; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE EXACERBATION; EOSINOPHIL; EOSINOPHILIA; FEMALE; INFLAMMATION; LUNG INFECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; VIRUS INFECTION;

EID: 0037111211     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.169.10.5458     Document Type: Article

References (45)

1. Holtzman, M. J., D. C. Look, M. F. Iademarco, D. C. Dean, D. Sampath, and M. Castro. 1998. Asthma. In Principles of Molecular Medicine. J. L. Jameson, ed. Humana, Totawa, NJ, p. 319.
2. Wang, J., K. Palmer, J. Lotvall, S. Milan, X. F. Lei, K. I. Matthaei, J. Gauldie, M. D. Inman, M. Jordana, and Z. Xing. 1998. Circulating, but not local lung, IL-5 is required for the development of antigen-induced airways eosinophilia. J. Clin. Invest. 102:1132.
3. Minshall, E. M., R. Schleimer, L. Cameron, M. Minnicozzi, R. W. Egan, J. C. Gutierrez-Ramos, D. H. Eidelman, and Q. Hamid. 1998. Interleukin-5 expression in the bone marrow of sensitized BALB/c mice after allergen challenge. Am. J. Respir. Crit. Care Med. 158:951.
4. Wills-Karp, M., J. Luyimbazi, X. Xu, B. Schofield, T. Y. Neben, C. L. Karp, and D. D. Donaldson. 1998. Interleukin-13: Central mediator of allergic asthma. Science 282:2258.
5. Swain, S. L., A. D. Weinberg, M. English, and G. Huston. 1990. IL-4 directs the development of Th2-like helper effectors. J. Immunol. 145:3796.
6. Brusselle, G., J. Kips, G. Joos, H. Bluethmann, and R. Pauwels. 1995. Allergen-induced airway inflammation and bronchial responsiveness in wild type and interleukin-4-deficient mice. Am. J. Respir. Cell Mol. Biol. 12:254.
7. Randolph, D. A., C. J. Carruthers, S. J. Szabo, K. M. Murphy, and D. D. Chaplin. 1999. Modulation of airway inflammation by passive transfer of allergen-specific Th1 and Th2 cells in a mouse model of asthma. J. Immunol. 162:2375.
8. Cohn, L., R. J. Homer, A. Marinov, J. Rankin, and K. Bottomly. 1997. Induction of airway mucus production by T helper 2 (Th2) cells: A critical role for interleukin 4 in cell recruitment but not mucus production. J. Exp. Med. 186:1737.
9. Austrup, F., D. Vestweber, E. Borges, M. Lohning, R. Brauer, U. Herz, H. Renz, R. Hallmann, A. Scheffold, A. Radbruch, and A. Hamann. 1997. P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues. Nature 385:81.
10. + T cells. J. Exp. Med. 189:1765.
11. Bradley, L. M., V. C. Asensio, L. K. Schioetz, J. Harbertson, T. Krahl, G. Patstone, N. Woolf, I. L. Campbell, and N. Sarvetnick. 1999. Islet-specific Th1, but not Th2, cells secrete multiple chemokines and promote rapid induction of autoimmune diabetes. J. Immunol. 162:2511.
12. Katakai, T., K. J. Mori, T. Masuda, and A. Shimizu. 1998. Differential localization of Th1 and Th2 cells in autoimmune gastritis. Int. Immunol. 10:1325.
13. D'Ambrosio, D., A. Iellem, L. Colantonio, B. Clissi, R. Pardi, and F. Sinigaglia. 2000. Localization of Th-cell subsets in inflammation: Differential thresholds for extravasation of Th1 and Th2 cells. Immunol. Today 21:183.
14. Bonecchi, R., G. Bianchi, P. P. Bordignon, D. D'Ambrosio, R. Lang, A. Borsatti, S. Sozzani, P. Allavena, P. A. Gray, A. Mantovani, and F. Sinigaglia. 1998. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. J. Exp. Med. 187:129.
15. + T lymphocytes with regulatory activity. J. Immunol. 166:996.
16. Clissi, B., D. D'Ambrosio, J. Geginat, L. Colantonio, A. Morrot, N. W. Freshney, J. Downward, F. Sinigaglia, and R. Pardi. 2000. Chemokines fail to up-regulate β1 integrin-dependent adhesion in human Th2 T lymphocytes. J. Immunol. 164:3292.
17. Wagner, F., N. Fischer, C. Lersch, R. Hart, and H. Dancygier. 1989. Interleukin 4 inhibits the interleukin 2-induced production of its functional antagonist, interferon gamma. Immunol. Lett. 21:237.
18. Cohn, L., R. J. Homer, N. Niu, and K. Bottomly. 1999. T helper 1 cells and interferon γ regulate allergic airway inflammation and mucus production. J. Exp. Med. 190:1309.
19. Snapper, C. M., and W. E. Paul. 1987. Interferon-γ and B cell stimulatory factor-1 reciprocally regulate Ig isotype production. Science 236:944.
20. + T cells reactive with Plasmodium chabaudi chabaudi: Distinct response kinetics for cells with Th1 and Th2 characteristics during infection. Int. Immunol. 1:416.
21. Randolph, D. A., R. Stephens, C. J. Carruthers, and D. D. Chaplin. 1999. Cooperation between Th1 and Th2 cells in a murine model of eosinophilic airway inflammation. J. Clin. Invest. 104:1021.
22. McIntosh, K., E. F. Ellis, L. S. Hoffman, T. G. Lybass, J. J. Eller, and V. A. Fulginiti. 1973. The association of viral and bacterial respiratory infections with exacerbations of wheezing in young asthmatic children. J. Pediatr. 82:578.
23. Lemanske, R. F., Jr., E. C. Dick, C. A. Swenson, R. F. Vrtis, and W. W. Busse. 1989. Rhinovirus upper respiratory infection increases airway hyperreactivity and late asthmatic reactions. J. Clin. Invest. 83:1.
24. Riedel, F., A. Krause, W. Slenczka, and C. H. Rieger. 1996. Parainfluenza-3-virus infection enhances allergic sensitization in the guinea pig. Clin. Exp. Allergy 26:603.
25. Schwarze, J., E. Hamelmann, K. L. Bradley, K. Takeda, and E. W. Gelfand. 1997. Respiratory syncytial virus infection results in airway hyperresponsiveness and enhanced airway sensitization to allergen. J. Clin. Invest. 100:226.
26. Micillo, E., A. Bianco, D. D'Auria, G. Mazzarella, G. Mazzarelia, and G. F. Abbate. 2000. Respiratory infections and asthma. Allergy 55:42.
27. low thymocytes in vivo. Science 250:1720.
28. + T cells. J. Exp. Med. 179:1539.
29. Garcia, S., J. DiSanto, and B. Stockinger. 1999. Following the development of a CD4 T cell response in vivo: From activation to memory formation. Immunity 11:163.
30. Haskins, K., R. Kubo, J. White, M. Pigeon, J. Kappler, and P. Marrack. 1983. The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody. J. Exp. Med. 157:1149.
31. Guler, M. L., J. D. Gorham, C. S. Hsieh, A. J. Mackey, R. G. Steen, W. F. Dietrich, and K. M. Murphy. 1996. Genetic susceptibility to Leishmania: IL-12 responsiveness in THI cell development. Science 271:984.
32. Rothenberg, M. E., J. A. MacLean, E. Pearlman, A. D. Luster, and P. Leder. 1997. Targeted disruption of the chemokine eotaxin partially reduces antigen-induced tissue eosinophilia. J. Exp. Med. 185:785.
33. Gonzalo, J. A., C. M. Lloyd, L. Kremer, E. Finger, A. C. Martinez, M. H. Siegelman, M. Cybulsky, and J. C. Gutierrez-Ramos. 1996. Eosinophil recruitment to the lung in a murine model of allergic inflammation: The role of T cells, chemokines, and adhesion receptors. J. Clin. Invest. 98:2332.
34. Gajewska, B. U., D. Alvarez, M. Vidric, S. Goncharova, M. R. Stampfli, A. J. Coyle, J. C. Gutierrez-Ramos, and M. Jordana. 2001. Generation of experimental allergic airways inflammation in the absence of draining lymph nodes. J. Clin. Invest. 108:577.
35. Foster, P. S., S. P. Hogan, A. J. Ramsay, K. I. Matthaei, and I. G. Young. 1996. Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J. Exp. Med. 183:195.
36. Yamaguchi, Y., T. Suda, J. Suda, M. Eguchi, Y. Miura, N. Harada, A. Tominaga, and K. Takatsu. 1988. Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursors. J. Exp. Med. 167:43.
37. Temann, U. A., G. P. Geba, J. A. Rankin, and R. A. Flavell. 1998. Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness. J. Exp. Med. 188:1307.
38. Zhu, Z., R. J. Homer, Z. Wang, Q. Chen, G. P. Geba, J. Wang, Y. Zhang, and J. A. Elias. 1999. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J. Clin. Invest. 103:779.
39. + T cell effectors can become memory cells with high efficiency and without further division. Nat. Immunol. 2:705.
40. Collins, P. D., S. Marleau, D. A. Griffiths-Johnson, P. J. Jose, and T. J. Williams. 1995. Cooperation between interleukin-5 and the chemokine cotaxin to induce eosinophil accumulation in vivo. J. Exp. Med. 182:1169.
41. Unutmaz, D., P. Pileri, and S. Abrignani. 1994. Antigen-independent activation of naive and memory resting T cells by a cytokine combination. J. Exp. Med. 180:1159.
42. Schmidt-Weber, C. B., S. I. Alexander, L. E. Henault, L. James, and A. H. Lichtman. 1999. IL-4 enhances IL-10 gene expression in murine Th2 cells in the absence of TCR engagement. J. Immunol. 162:238.
43. + T cells: Evidence for two distinct pathways for promoter activation. Eur. J. Immunol. 29:548.
44. Evavold, B. D., J. Sloan-Lancaster, B. L. Hsu, and P. M. Allen. 1993. Separation of T helper 1 clone cytolysis from proliferation and lymphokine production using analog peptides. J. Immunol. 150:3131.
45. Stephens, R., and D. D. Chaplin. 2002. IgE cross-linking or lipopolysaccharide treatment induces recruitment of Th2 cells to the lung in the absence of specific antigen. J. Immunol. 169:5468.