Massive cell death of cerebellar granule neurons accompanied with caspase-3-like protease activation and subsequent motor discoordination after intracerebroventricular injection of vincristine in mice

Neuroscience

Volumn 115, Issue 1, 2002, Pages 55-65

  Shimizu, H ^a   Ohgoh, M ^a   Momose, Y ^a   Nishizawa, Y ^a   Ogura, H ^a  

^a EISAI CO LTD   (Japan)

Author keywords

Apoptosis; Caspase; Cerebellar granule cells; Motor discoordination; Vincristine

Indexed keywords

CASPASE 3 LIKE PROTEASE; PROTEINASE; UNCLASSIFIED DRUG; VINCRISTINE;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CEREBELLUM; CHROMATIN CONDENSATION; CONTROLLED STUDY; DRUG EFFECT; ELECTRON MICROSCOPY; ENZYME ACTIVATION; ENZYME ACTIVITY; GRANULE CELL; HEAD MOVEMENT; HISTOPATHOLOGY; MALE; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; MOUSE; NERVE CELL NECROSIS; NERVE DEGENERATION; NICK END LABELING; NONHUMAN; NUCLEOSOME; PRIORITY JOURNAL; ROTATION; TASK PERFORMANCE; WALKING;

ANIMALS; CASPASE 3; CASPASES; CELL DEATH; CEREBELLUM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPEPTIDASES; ENZYME ACTIVATION; INJECTIONS, INTRAVENTRICULAR; MALE; MICE; MICE, INBRED ICR; MOTOR SKILLS DISORDERS; NEURONS; VINCRISTINE;

EID: 0037110656     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(02)00403-7     Document Type: Article

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