Spatial learning deficits in rats after injection of vincristine into the dorsal hippocampus

Neuroscience

Volumn 91, Issue 4, 1999, Pages 1299-1313

  Eijkenboom, M ^a   Van Der Staay, F J ^a  

^a BAYER AG   (Germany)

Author keywords

Dorsal hippocampus; Microtubule poison; Morris water maze; Rat; Spatial learning; Vincristine

Indexed keywords

VINCRISTINE;

AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX LESION; BRAIN INJURY; COGNITIVE DEFECT; CONTROLLED STUDY; DENTATE GYRUS; HIPPOCAMPUS; LEARNING DISORDER; MALE; MOTOR DYSFUNCTION; NERVE CELL LESION; NERVE FIBER TRANSPORT; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ESCAPE REACTION; HIPPOCAMPUS; INJECTIONS; LEARNING DISORDERS; MALE; MAZE LEARNING; NEUROTOXINS; OSMOLAR CONCENTRATION; RATS; RATS, WISTAR; SWIMMING; VINCRISTINE;

EID: 0032906062     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(98)00657-5     Document Type: Article

References (37)

1. Amaral D.G., Witter M.P. The three-dimensional organization of the hippocampal formation: a review of anatomical data. Neuroscience. 31:1997;571-591.
2. Babcock A.M., Baker D.A., Lovec R. Locomotor activity in the ischemic gerbil. Brain Res. 625:1993;351-354.
3. Barnes C.A. Spatial learning and memory processes: the search for their neurobiological mechanisms in the rat. Trends Neurosci. 11:1988;163-169.
4. Bunsey M., Eichenbaum H. Conservation of hippocampal memory function in rats and humans. Nature. 379:1996;255-257.
5. Chozick B.S. The behavioural effects of lesions of the hippocampus: a review. Int. J. Neurosci. 22:1983;63-80.
6. Dasheiff R.M., Ramirez L.F. The effects of colchicine in mammalian brain from rodents to rhesus monkeys. Brain Res. Rev. 10:1985;47-67.
7. Di Patre P.L., Abbamondi A., Bartolini L., Pepeu G. GM1 ganglioside counteracts cholinergic and behavioral deficits in the rat induced by intracerebral injection of vincristine. Eur. J. Pharmac. 162:1989;43-50.
8. Finger S., Green L., Tarnoff M.E., Mortman K.D., Andersen A. Nimodipine enhances new learning after hippocampal damage. Expl Neurol. 109:1990;279-285.
9. Freund R. J. and Littell R. C. (1985) SAS for Linear Models. SAS Institute, Cary, NC.
10. Goldschmidt R.B., Steward O. Comparison of the neurotoxic effects of colchicine, the vinca alkaloids, and other microtubule poisons. Brain Res. 486:1989;133-140.
11. Jarrard L.E. What does the hippocampus really do? Behav. Brain Res. 71:1995;1-10.
12. Klapdor K., Dulfer B.G., Hammann A., van der Staay F.J. A low-cost method to analyse footprint patterns. J. Neurosci. Meth. 75:1997;49-54.
13. Kozik M.B., Maziarz L. Morphological and histochemical changes in the rat's brain induced by vincristine administered in early periods of postnatal development. Folia morph. XLII:1983;199-216.
14. Kozik M.B., Szczech J. Histoenzymatic and morphometric changes occurring in nerve cells of gyrus cinguli following treatment of young rats with vincristine. Expl Path. 24:1983;243-252.
15. Legha S.S. Vincristine neuropathy: pathophysiology and management. Med. Toxic. 1:1986;421-427.
16. Markus E.J., Qin Y.-L., Leonard B., Skaggs W.E., McNaughton B.L., Barnes C.A. Interactions between location and task affect the spatial and directional firing of hippocampal neurons. J. Neurosci. 15:1995;7079-7094.
17. Morris R. Development of a water-maze procedure for studying spatial learning in the rat. J. Neurosci. Meth. 11:1984;47-60.
18. Morris R.G.M., Schenk F., Tweedie F., Jarrard L.E. Ibotenate lesions of hippocampus and/or subiculum: dissociating components of allocentric spatial learning. Eur. J. Neurosci. 2:1990;1016-1028.
19. Moser E., Moser M., Andersen P. Spatial learning impairment parallels the magnitude of dorsal hippocampal lesions, but is hardly present following ventral lesions. J. Neurosci. 13:1993;3916-3925.
20. Moser M.-B., Moser E.I., Forrest E., Andersen P., Morris R.G. Spatial learning with a minislab in the dorsal hippocampus. Proc. natn. Acad. Sci. U.S.A. 92:1995;9697-9701.
21. O'Keefe J. and Nadel L. (1978) The Hippocampus as a Cognitive Map, pp. 291-315. Clarendon, Oxford.
22. Olton D.S., Becker J.T., Handelmann G.E. Hippocampus, space, and memory. Behav. Brain Sci. 2:1979;313-365.
23. Olton D.S., Papas B.C. Spatial memory and hippocampal function. Neuropsychologia. 17:1979;669-682.
24. Paxinos G. and Watson C. (1986) The Rat Brain in Stereotaxic Coordinates. Academic, San Diego.
25. Sahenk Z., Brady S.T., Mendell J.R. Studies on the pathogenesis of vincristine-induced neuropathy. Muscle and Nerve. 10:1987;80-84.
26. Save E., Poucet B., Foreman N., Buhot M.C. Object exploration and reactions to spatial and nonspatial changes in hooded rats following damage to parietal cortex or hippocampal formation. Behav. Neurosci. 106:1992;447-456.
27. Schmued L.C., Albertson C., Slikker W.J. Fluoro-jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration. Brain Res. 751:1997;37-46.
28. Shiraishi S., Le Quesne P.M., Gajree T. The effect of vincristine on nerve regeneration in the rat. An electrophysiological study. J. neurol. Sci. 71:1985;9-17.
29. Shiraishi S., Le Quesne P.M., Gajree T., Cavanagh J.B. Morphometric effects of vincristine on nerve regeneration in the rat. J. neurol. Sci. 71:1985;165-181.
30. Skinner D.M., van der Kooy D. Acquisition and retention of negative patterning in hippocampal-lesioned rats. Psychobiology. 25:1997;10-17.
31. Stubley-Weatherly L.A., Harding J.W., Wright J.W. Effects of discrete kainic acid-induced hippocampal lesions on spatial and contextual learning and memory in rats. Brain Res. 716:1996;29-38.
32. Szczech J. Morphometric, karyometric and cytophotometric studies on spinal cord neurons and glia cells after vincristine administration. J. Hirnforsch. 5:1985;565-572.
33. Terranova J.P., Perio A., Worms P., Le Fur G., Soubrie P. Social olfactory recognition in rodents: deterioration with age, cerebral ischaemia and septal lesion. Behav. Pharmac. 5:1994;90-98.
34. Thinus-Blanc C., Save E., Buhot M. C. and Poucet B. (1991) The hippocampus, exploratory activity, and spatial memory. In Brain and Space (ed. Paillard J.), pp. 334-352. Oxford University Press, New York.
35. Tomiwa K., Hazama F., Mikawa H. Neurotoxicity of vincristine after the osmotic opening of the blood-brain barrier. Neuropath. appl. Neurobiol. 9:1983;345-354.
36. Wang D., Corbett D. Cerebral ischemia, locomotor activity and spatial mapping. Brain Res. 533:1990;78-82.
37. Witter M.P., Groenewegen H.J., Lopes da Silva F.H., Lohman A.H.M. Functional organization of the extrinsic and intrinsic circuitry of the parahippocampal region. Prog. Neurobiol. 33:1989;161-253.