Strong aggregation and increased toxicity of polyleucine over polyglutamine stretches in mammalian cells

Human Molecular Genetics

Volumn 11, Issue 13, 2002, Pages 1487-1496

  Dorsman, Josephine C ^a,b   Pepers, Barry ^a   Langenberg, Dennis ^a   Kerkdijk, Henri ^a   Ijszenga, Marije ^a   Den Dunnen, Johan T ^a   Roos, R A C ^a   Van Ommen, Gert Jan B ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; GLUTAMINE; LEUCINE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 1C2; POLYGLUTAMINE; POLYLEUCINE; POLYPEPTIDE; REPETITIVE DNA; UNCLASSIFIED DRUG;

ARTICLE; BIOCHEMISTRY; CONTROLLED STUDY; CYTOTOXICITY; DEGENERATIVE DISEASE; HUMAN; HUMAN CELL; HUNTINGTON CHOREA; HYDROPHILICITY; HYDROPHOBICITY; MAMMAL CELL; MOLECULAR RECOGNITION; MOLECULAR SIZE; OCULOPHARYNGEAL MUSCULAR DYSTROPHY; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN EXPRESSION;

MAMMALIA;

EID: 0037096832     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/11.13.1487     Document Type: Article

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