Scavenger receptor class B type I expression and elemental analysis in cerebellum and parietal cortex regions of the Alzheimer's disease brain

Journal of the Neurological Sciences

Volumn 196, Issue 1-2, 2002, Pages 45-52

  Srivastava, Rai Ajit K ^a,c   Jain, Jinesh C ^b  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b University of Notre Dame   (United States)

^c Esperion Therapeutics Inc   (United States)

Author keywords

Alzhemier's disease; Brain; Elemental analysis; Oxidative stress; Scavenger receptor class B type I

Indexed keywords

ALUMINUM; AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; BORON; CHROMIUM; IRON; MANGANESE; METAL ION; RECEPTOR SUBTYPE; SCAVENGER RECEPTOR; SILICON; SODIUM ION; TELLURIUM; TIN;

AGED; ALZHEIMER DISEASE; ATOMIC EMISSION SPECTROMETRY; BRAIN REGION; BRAIN TISSUE; CEREBELLUM; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; DEGENERATIVE DISEASE; DISEASE COURSE; FEMALE; HUMAN; HUMAN TISSUE; PARIETAL LOBE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AGED; AGED, 80 AND OVER; ALUMINUM; ALZHEIMER DISEASE; ANTIGENS, CD36; CEREBELLUM; FEMALE; HUMANS; IONS; LIPOPROTEINS; MANGANESE; MEMBRANE PROTEINS; METALS; OXIDATIVE STRESS; PARIETAL LOBE; REACTIVE OXYGEN SPECIES; RECEPTORS, IMMUNOLOGIC; RECEPTORS, LIPOPROTEIN; RECEPTORS, SCAVENGER; SCAVENGER RECEPTORS, CLASS B; SILICON; SUPEROXIDE DISMUTASE; UP-REGULATION;

EID: 0037090595     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-510X(02)00026-6     Document Type: Conference Paper

References (51)

1. Alzheimer's disease and soluble A beta
2. Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer's disease
3. Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer's disease
4. The Aβ peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction
5. The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I)
6. Treatment with a copper-zinc chelator markedly and rapidly inhibits beta amyloid protein in Alzheimer's disease transgenic mice
7. L-Neurotoxic Aβ peptides increase oxidative stress in vivo through NMDA-receptor and nitric-oxide-synthase mechanisms, and inhibit complex IV and induce a mitochondrial permeability transition in vitro
8. Serum levels of iron binding protein p97 are elevated in Alzheimer's disease
9. Neurofibrillary pathology and aluminum in Alzheimer's disease
10. Serum aluminum levels in Alzheimer's disease and other senile dementias
11. Modification of the blood-brain barrier through chronic intoxication by aluminum glutamate: Possible role in the etiology of Alzheimer's disease
12. Aluminum modifies the properties of Alzheimer's disease PHF tau proteins in vivo and in vitro
13. Hippocampal tin, aluminum, and zinc in Alzheimer's disease
14. Copper, iron, and zinc imbalances in Alzheimer's disease: Possible relation to oxidative stress
15. LDL oxidation by arterial wall macrophages depends on the oxidant status in the lipoproteins and in the cells: Role of prooxidant vs. antioxidant
16. Identification of scavenger receptor SR-BI as a high density lipoprotein receptor
17. Scavenger receptor B1 mediates the selective uptake of oxidized cholesterol esters by rat liver
18. Binding and degradation of low-density lipoprotein by cultured human fibroblasts: Comparison of cells from normal subject and from a patient with homozygous familial hypercholesterolemia
19. Expression of alpha-2 macroglobulin receptor/low density lipoprotein receptor-related protein (LRP) in rat microglial cells
20. Modulation of β-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP)
21. Scavenger receptor class B, type I is expressed in porcine brain capillary endothelial cells and contributes to selective uptake of HDL-associated vitamin E
22. Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor
23. Age-related changes in the concentrations of major and trace elements in the brain of rats and mice
24. Expression of low density lipoprotein receptor, apolipoprotein AI, AII, and AIV in various rat organs utilizing an efficient method for RNA isolation
25. Using riboprobes for Northern blotting
26. Expression of LDL receptor, apolipoprotein B, apolipoprotein AI and apolipoprotein AIV genes in various organs of mouse as determined by a novel solution hybridization assay
27. Quantitation of absolute amounts of cellular messenger RNA by RNA - Excess solution hybridization with riboprobes
28. Estrogen increases hepatic lipase levels in inbred strains of mice: A possible mechanism for estrogen-dependent lowering of high-density lipoprotein
29. Accumulation of aluminum and silicon in lipofuscin granules suggests retardation of blood-brain barrier function in aging
30. Aluminum detected in senile plaques and neurofibrillary tangles is contained in lipofuscin granules with silicon, probably as aluminosilicates
31. The chemistry of aluminum and silicon in relation to Alzheimer's disease
32. Aluminosilicates and senile plaque formation in Alzheimer's disease
33. CSF silicon in dementia: A prospective study
34. Tin and fatty acids in dementia
35. Hippocampal tin, aluminum and zinc in Alzheimer's disease
36. Application of long-term cultured neurons in aging and neurological research: Aluminum neurotoxicity, synaptic degeneration and Alzheimer's disease
37. Aluminum binds to the hyper-phosphorylated tau in Alzheimer's disease: A hypothesis
38. Nitration of manganese superoxide dismutase in cerebrospinal fluids is a marker for peroxynitrite-mediated oxidative stress in neurodegenerative diseases
39. Non-haem iron histochemistry of the normal and Alzheimer's disease hippocampus
40. Localization of manganese superoxide dismutase in the cerebral cortex and hippocampus of Alzheimer-type senile dementia
41. Alzheimer's disease, Kuf's disease, tellurium and selenium
42. Glycoprotein 330/megalin: Probable role in receptor-mediated transport of apolipoprotein J alone and in a complex with Alzheimer's disease amyloid β at the blood-brain and blood-cerebrospinal fluid barriers
43. Glycoprotein 330/megalin (LRP-2) has low prevalence as mRNA and protein in brain microvessels and choroids plexus
44. Mutations in ABC1 in Tangier disease and familial high density lipoprotein deficiency
45. The gene encoding ATP binding cassette transporter 1 is mutated in Tangier disease
46. Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1
47. Transport of lipids from Golgi to plasma membrane is defective in tangier disease patients and in ABC1-deficient mice
48. Beta-amyloid protein enhances macrophage production of oxygen free radicals and glutamate
49. Proinflammatory cytokine expression contributes to brain injury provoked by chronic monocyte activation
50. Involvement of nitric oxide released from microglia-macrophages in pathological changes of cathepsin D-deficient mice
51. Celatrol, a potent antioxidant and anti-inflammatory drug, as a possible treatment of Alzheimer's disease