Identification of T cell determinants on human type II collagen recognized by HLA-DQ8 and HLA-DQ6 transgenic mice

Journal of Immunology

Volumn 163, Issue 3, 1999, Pages 1661-1665

  Krco, Christopher J ^a   Watanabe, Shohei ^a   Harders, Jerry ^a   Griffths, Marie M ^b   Luthra, Harvinder ^c   David, Chella S ^a,b  

^a MAYO GRADUATE SCHOOL   (United States)

^b MAYO CLINIC   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 2; HLA DQ ANTIGEN;

ANIMAL EXPERIMENT; ARTHRITIS; ARTICLE; AUTOIMMUNITY; HLA SYSTEM; IMMUNOGENICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; T LYMPHOCYTE; TRANSGENIC MOUSE;

AMINO ACID SEQUENCE; ANIMALS; CELLS, CULTURED; COLLAGEN; EPITOPES, T-LYMPHOCYTE; HLA-DQ ANTIGENS; HUMANS; INJECTIONS, SUBCUTANEOUS; LYMPHOCYTE ACTIVATION; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN BINDING; T-LYMPHOCYTES;

EID: 0033179436     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Stockwell, R. A. 1979. Biology of Cartilage Cells. Cambridge University Press, Cambridge.
2. Prockop, D. J., and K. I. Kivirikko. 1984. Heritable diseases of collagen. N. Engl. J. Med. 311:376.
3. Clague, R. B., S. A. Firth, P. J. L. Holt, J. Skingle, C. L. Greenbury, and M. Webly. 1983. Serum antibodies to type II collagen in rheumatoid arthritis comparison of six immunologic methods and clinical features. Ann. Rheum. Dis. 42:537.
4. Trentham, D. E., G. M. Kammer, W. J. McCune, and J.R. David. 1981. Autoimmunity to collagen: a shared feaure of psoriatic and rheumatoid arthritis. Arthritis Rheum. 24:1363.
5. 125I radioimmunoassay. Arthritis Rheum. 26:832.
6. Eklayam, O., H. Zinger, E. Zisman, R. Segal, M. Taron, C. Brautbar, and E. Moses. 1991. Regulatory T cell activity specific to human type II and II collagens in rheumatoid arthritis. J. Rheumatol. 18:516.
7. Londei, M., C. M. Savill, A. Averhoef, F. Brennan, Z. A. Leech, V. Duance, R. N. Maini, and M. Feldmann. 1989. Persistence of collagen type II-specific T cell clones in the synovial membrane of a patient with rheumatoid arthritis. Proc. Natl. Acad. Sci. USA 86:636.
8. Trentham, D. E., A. S. Townes, and A.H. Kang. 1977. Autoimmunity to type II collagen: an experimental model of arthritis. J. Exp. Med. 146:857.
9. Stuart, J. M., W. C. Watson, and A. H. Kang. 1988. Collagen autoimmunity and arthritis. FASEB J. 2:2950.
10. Courtenay, J. S., M. J. Dallman, A. D. Dayan, A. Martin, and B. Mosedale. 1980. Immunization against heterologous type II collagen induces arthritis in mice. Nature 283:666.
11. Wooley, P. H., H. S. Luthra, J. M. Stuart, and C. S. David. 1981. Type II collagen-induced arthritis in mice. I. Major histocompatibility complex (I region) linkage and antibody correlates. J. Exp. Med. 154:688.
12. Wooley, P. H., A. M. Dillon, H. S. Luthra, J. M. Stuart, and C. S. David. 1983. Genetic control of the type II collagen-induced arthritis in mice: factors influencing disease susceptibility and evidence for multiple MHC-associated gene control. Transplant. Proc 157:180.
13. David, C. S. 1990. Genes for MHC, TCR, and MIs determine susceptibility to collagen-induced arthritis. APMIS 98:575.
14. Wordsworth, B. P. 1991. HLA class II antigens in susceptibility to rheumatoid arthrits. Br. J. Rheumatol. 30:151.
15. Wordsworth, B. P., L. J. Sakkas, L.I. Welsh, K. I. Panayi, and J. I. Bell. 1989. HLA-DR4 subtype frequencies in rheumatoid arthritis indicate that DRB1 is the major susceptibility locus within the HLA class II region. Proc. Natl. Acad. Sci. USA 86:10049.
16. Nepom, G. T., and H. J. Nepom. 1987. The molecular basis for HLA class II associations with rheumatoid arthritis. J. Clin. Immunol. 7:1.
17. Harley, J. B., M. Reichlin, F. C., Arnett, E. L. Alexander, W. B. Bias, and T. T. Provist. 1986. Gene interaction at HLKA-DQ enhances autoantibody production in primary Sjogren's syndrome. Science 232:1145.
18. Bell, J., L. Rassenti, S. Smoot, K. Smith, C. Newby, R. Hohfeld, K. Toyka, H. McDevitt, and L. Steinman. 1986. HLA-DQ β-chain polymorphism linked to myasthenia gravis. Lancet i:1058.
19. Welsh, E. A., H. H. Clark, S. Z. Epstein, J. D. Reveile, and M. Duvic. 1994. Human leukocyte antigen-DQB1*03 alleles are associated with alopecia areata. J. Invest. Dermatol. 103:758.
20. Baisch, J. M., T. Weeks, R. Giles, M. Hoover, P. Stastny, and J. D. Capra. 1990. Analysis of HLA-DQ genotypes and susceptibility in insulin-dependent diabetes mellitus. N. Engl. J. Med. 322:1836.
21. Illonen, J. R. H., H. Arvilommi, I. Jokinen, T. Mottonen, and P. Hannonen. 1990. HLA-DR antigens and HLA-DQ β chain polymorphisms in susceptibility to rheumatoid arthritis. Ann. Rheum. Dis. 49:494.
22. Zanelli, E., M. A. Gonzalez-Gay, and C. S. David. 1995. Could HLA-DRB1 be the protective locus in rheumatoid arthritis? Immunol. Today 16:274.
23. Zanelli, E., C. J. Krco, J. M. Baisch, S. Cheng, and C. S. David. 1996. Immune response of HLA-DQ8 transgenic mice to peptides from the third hypervariable region of the HLA-DRB1 correlates with predisposition to rheumatoid arthritis Proc. Natl. Acad. Sci. USA 93:1814.
24. + T cells in transgenic mice. Immunogenetics 35:219.
25. Nabozny, G. H., J. M. Baisch, S. Cheng, D. Cosgrove, M. M. Griffiths, H. S. Luthra, and C. S. David. 1996. HLA-DQ8 transgenic mice are highly susceptible to collagen-induced arthritis: a novel model for human polyarthritis. J. Exp. Med. 183:27.
26. Krco, C. J., J. Pawelski, J. Harders, D. McCormick, M. Griffths, H. S. Luthra, and C. S. David. 1996. Characterization of the antigenic structure of human type II collagen. J. Immunol. 156:2761.
27. Matsushita, S., T. Nishi, M. Oiso, K. Yamaoka, K. Yone, T. Kanai, and Y. Nishimura. 1996. HLA-DQ-binding peptide motifs. I. Comparative binding analysis of type II collagen-derived peptides to DR and DQ molecules of rheumatoid arthritis-susceptible and nonsusceptible haplotypes. Int. Immunol. 8:757.
28. Fugger, L., J. B. Rothbard, and G. Sonderstrup-McDevitt. 1996. Specificity of an HLA-DRB1*0401-restricted T cell response to type II collagen. Eur. J. Immunol. 26:928.
29. Andersson, E. C., B. E. Hansen, H. Jacobsen, L. S. Madsen, C. B. Andersen, J. Engberg, J. B. Rothbard, G. Sonderstrup-McDevitt, V. Malmstrom, R. Holmdahl, et al. 1998. Definition of MHC and T cell receptor contacts in the HLA-DR4-restricted immunodominant epitope in type II collagen and characterization of collagen-induced arthritis in HLA-DR4 and human CD4 transgenic mice. Proc. Natl. Acad. Sci. USA 95:7574.
30. Rosloniec, E. F., D. D. Brand, L. K. Meyers, Y. Esaki, K. B. Whittington, D. M. Zaller, A. Woods, J. M. Stuart, and A. H. Kang. 1998. Induction of autoimmune arthritis in HLA-DR4 (DRB1*0401) transgenic mice by immunization with human and bovine type II collagen. J. Immunol. 160:2573.
31. Bradley, D. S., D. Das, M. M. Griffiths, H. S. Luthra, and C. S. David. 1998. HLA-DQ6/8 double transgenic mice develop auricular chondritis following type II collagen immunization: a model for human relapsing polychondritis. J. Immunol. 161:5046.