Minor histocompatibility antigen-specific MHC-restricted CD8 T cell responses elicited by heat shock proteins

Journal of Immunology

Volumn 168, Issue 4, 2002, Pages 1697-1703

  Robert, Jacques ^a   Gantress, Jennifer ^a   Rau, Laura ^a   Bell, Alisa ^a   Cohen, Nicholas ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; CHAPERONE; GLYCOPROTEIN GP 96; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 70; MINOR HISTOCOMPATIBILITY ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; GRAFT REJECTION; IMMUNE RESPONSE; IMMUNOCOMPETENCE; IMMUNOGENICITY; LARVA; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PRIORITY JOURNAL; SKIN GRAFT; T LYMPHOCYTE; XENOPUS;

EID: 0037083584     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.4.1697     Document Type: Article

References (58)

1. Heat shock proteins come of age: Primitive functions acquire new roles in an adaptive world
2. Gp96 is the Swiss army knife of the immune system
3. Biochemical, cell biological and immunological issues surrounding the endoplasmic reticulum chaperone GRP94/gp96
4. Immunotherapy of tumors with autologous tumor-derived heat shock protein preparations
5. Heat shock protein 72 on tumor cells a recognition structure for NK cells
6. Necrotic but not apoptotic cell death releases heat shock proteins, which deliver a partial maturation signal to dendritic cells and activate the NF-κB pathway
7. Heat shock proteins transfer peptides during antigen processing and CTL priming
8. + T cell in vivo
9. Hsp 72-mediated augmentation of MHC class I surface expression and endogenous antigen presentation
10. Immunization with a lymphocytic choriomeningitis virus peptide mixed with heat shock protein 70 results in protective antiviral immunity specific cytotoxic T lymphocytes
11. Isolation of an immunodominant viral peptide that is endogenously bound to the stress protein gp96/grp94
12. Cross-priming of minor histocompatibility antigen-specific cytotoxic T cells upon immunization with the heat shock protein gp96
13. A mechanism for the specific immunogenicity of heat shock protein-chaperoned peptides
14. The endoplasmic reticulum-resident stress protein gp96 binds peptides translocated by TAP
15. Heat shock protein-peptide complexes, reconstituted in vitro, elicit peptide-specific cytotoxic T lymphocyte response and tumor immunity
16. Cutting edge: Receptor-mediated endocytosis of heat shock proteins by professional APCs
17. Receptor mediated and fluid phase pathways for internalization of the ER Hsp90 chaperone GRP94 in murine macrophages
18. Receptor-mediated uptake of antigen/heat shock protein complexes results in major histocompatibility complex class I antigen presentation via two distinct processing pathways
19. CD91: A receptor for heat shock protein gp96
20. Tumor-specific immunogenicity of stress-induced proteins: Convergence of two evolutionary pathways of antigen presentation?
21. Evolution of immune surveillance and tumor immunity: Studies in Xenopus
22. Phylogenetic conservation of the molecular and immunological properties of the chaperones gp96 and hsp70
23. The immune system of Xenopus
24. Lymphoid tumors of Xenopus laevis with different capacities for growth in larvae and adults
25. Production of large clones of histocompatible, fully identical clawed toads (Xenopus)
26. Xenopus lymphoid tumor cell lines
27. Purification of immunogenic heat shock protein 70-peptide complexes by ADP-affinity chromatography
28. Reagents specific for MHC 1 antigens of Xenopus
29. Analysis of T cell development in Xenopus
30. Identification of a candidate CD5 homolog in the amphibian Xenopus laevis
31. A cell surface marker of thymus dependent lymphocytes in Xenopus laevis is identified by mouse monoclonal antibody
32. Studies in Xenopus immunoglobulins using monoclonal antibodies
33. Active suppression of allogeneic histocompatibility reactions during metamorphosis of the clawed toad Xenopus
34. Mitogen activated Xenopus laevis lymphocytes produce a T cell growth factor
35. The JAM test: A simple assay for DNA fragmentation and cell death
36. Genetic aspects of the tolerance to allografts induced at metamorphosis in the toad Xenopus laevis
37. Complete abrogation of immune responses to skin allografts and rabbit erythrocytes in the early thymectomized Xenopus
38. Thymus dependency of transplantation allo-tolerance in the metamorphosing frog, Xenopus laevis
39. Response to skin allografts in Xenopus laevis following thymectomy at early stages of lymphoid organ maturation
40. MHC restricted and unrestricted CD8 T-cells: An evolutionary perspective
41. Immune response of thymus/lymphocyte embryonic chimeras: Studies on tolerance and major histocompatibility complex restriction
42. Impaired rejection of minor histocompatibility antigen-disparate skin grafts and acquisition of tolerance to thymus donor antigens in allothymus-implanted, thymectomized Xenopus
43. Immunogenetic studies on the cell-mediated cytotoxicity in the clawed toad Xenopus laevis
44. In vitro correlates of in vivo skin graft rejection in Xenopus
45. In vitro proliferation and cytotoxic responses against Xenopus minor histocompatibility antigens
46. Expression of MHC class II antigens during Xenopus development
47. MHC-encoded class I molecules are absent in immunologically competent Xenopus before metamorphosis
48. Changes in the immune system during metamorphosis of Xenopus
49. Expression of MHC class Ia and class Ib during ontogeny: High expression in epithelia and coregulation of class Ia and lmp7 genes
50. Involvement of thyroid hormones in the expression of MHC class I antigens during ontogeny of Xenopus
51. Development and analysis of various clonal alloantigen-dependent cytotoxic cell lines from channel catfish
52. Natural cytotoxicity towards allogeneic tumour targets in Xenopus mediated by diverse splenocyte populations
53. Xenopus NK cells identified by novel monoclonal antibodies
54. In vitro cytotoxicity in adult Xenopus generated against larval targets and minor histocompatibility antigens
55. Ontogeny and thymus-dependence of T-cell surface antigens in Xenopus: Flow cytometric studies on monoclonal antibody-stained thymus and spleen
56. In vitro thymocyte differentiation in MHC class I-negative Xenopus larvae
57. Induction of thymocyte differentiation and proliferation in vitro by PMA/ionophore correlates with a down-regulation of CTX expression in Xenopus
58. Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability