A t(4;11)(q21;p15) in a case of T-cell lymphoma and a case of acute myelogenous leukemia

Cancer Genetics and Cytogenetics

Volumn 132, Issue 2, 2002, Pages 109-115

  Thangavelu, Maya ^a   Huang, Bing ^a   Lemieux, Marilyn ^a   Tom, Winston ^a   Richkind, Kathleen E ^a  

^a GENZYME GENETICS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD5 ANTIGEN; CD56 ANTIGEN; CD7 ANTIGEN; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; CYCLOSPORIN; CYTARABINE; DOXORUBICIN; IDARUBICIN; METHOTREXATE; MITOXANTRONE; PREDNISONE; VINCRISTINE;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; ALLOGENIC BONE MARROW TRANSPLANTATION; ARTICLE; CASE REPORT; CHROMOSOME 11; CHROMOSOME 4; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; CYTOGENETICS; FLUORESCENCE IN SITU HYBRIDIZATION; GRAFT VERSUS HOST REACTION; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; KARYOTYPE; MALE; METAPHASE; PRIORITY JOURNAL; RECURRENT CANCER; SCHOOL CHILD; T CELL LYMPHOMA;

ADOLESCENT; ADULT; CHILD; CHROMOSOMES, HUMAN, PAIR 11; CHROMOSOMES, HUMAN, PAIR 4; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; LEUKEMIA, MYELOCYTIC, ACUTE; LYMPHOMA, T-CELL; MALE; MIDDLE AGED; TRANSLOCATION, GENETIC;

EID: 0037081764     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-4608(01)00534-9     Document Type: Article

References (33)

1. The (4;11)(q21;p15) translocation fuses the NUP98 and RAP1G genes and is recurrent in T-cell acute lymphocytic leukemia
2. t(4;11)(q21;p15) translocation involving NUP98 and RAP1GDS1 genes; characterization of a new subset of T acute lymphoblastic leukemia
3. The (4;11) translocation in acute leukemia of childhood; the importance of additional chromosomal aberrations
4. Chromosomal abnormalities identify high risk and low risk patients with acute lymphoblatic leukemia
5. A rare translocation (4;11)(q21;p14-15) in an acute lymphoblastic leukemia expressing T-cell and myeloid markers
6. Characterization of childhood acute leukemia with multiple myeloid and lymphoid markers at diagnosis and at relapse
7. A variant translocation between chromosomes 4 and 11, t(4q;11p) in a child with acute leukemia
8. The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene
9. Acute mixed lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product
10. The der(11)-encoded MLL/AF-4 fusion transcript is consistently detected in t(4;11)(q21;q23)-containing acute lymphoblastic leukemia
11. The vertebrate GLFG nucleoporin, Nup98, is an essential component of multiple RNA export pathways
12. Nucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus type 1
13. Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11) (p15;p15) in human myeloid leukemia
14. The t(7;11)(p15;15) translocation in acute myeloid leukemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9
15. The inv(11)(p15q22) chromosome translocation of de novo and therapy-related myeloid malignancies results in fusion of the nucleoporin gene, NUP98, and the putative RNA helicase gene, DDX10
16. Clinical haematological and molecular studies in patients with chromosome translocation t(7;11); a study of four Chinese patients from Taiwan
17. NUP98-HOXD13 gene fusion in therapy-related acute myelogenous leukemia
18. NUP98 is fused to PMX1 homeobox gene in human acute myelogenous leukemia with chromosome translocation t(1;11)(q23;p15)
19. The t(11;20)(p15;q11) chromosomal translocation associated with therapy-related myelodysplastic syndrome results in NUP98-TOP1 fusion
20. Chronic myelomonocytic leukemia with t(7;11)(p15;p15) and NUP98/HOXA9 fusion
21. Heterogenous fusion transcripts involving the NUP98 gene and HOXD13 gene activation in a case of acute myeloid leukemia with the t(2;11)(q31;p15) translocation
22. Translocation (1;11)(q23;p15), a novel simple variant of translocation (7;11)(p15;p15), in a patient with AML (M2) accompanied by non-Hodgkin lymphoma and gastric cancer
23. Expression of the NUP98/HOXA9 fusion transcript in the blast crisis of Philadelphia chromosome-positive chronic myelogenous leukemia with t(7;11)(p15;15)
24. t(9;11)(p22;p15) in acute myeloid leukemia results in a fusion between NUP98 and the gene encoding transcriptional coactivator p52 and p75-lens epithelium-derived growth factor (LEDGF)
25. Fusion of the nucleoporin gene, NUP98 and the putative RNA helicase gene, DDX10, by inversion 11(p15q22) chromosome translocation in a patient with etoposide-related myelodysplastic syndrome
26. Potential role for DNA topoisomerase II poisons in the generation of t(11;20)(p15;q11) translocations
27. A stimulatory CDP/GTP exchange protein for smg p21 is active on the post-transcriptionally processed form of c-Ki-ras p21 and rhoA p21
28. Myelodysplasia following treatment of chronic lymphocytic leukemia (CLL) with 2-chlorodeoxyadenosine (2-cdA)
29. Philadelphia-like translocation t(9;22)(q34;q11) found in a follicular lymphoma involving not BCR and ABL but ICL-mediated rearrangement of an unknown gene on 9q34
30. A novel translocation (3;11)(q26;q13) in a case of acute myelomonocytic leukemia
31. A recurrent translocation, t(3;11)(q21;q13) found in two distinct cases of acute myeloid leukemia