Philadelphia-like translocation t(9;22)(q34;qII) found in a follicular lymphoma involving not BCR and ABL but IGL-mediated rearrangement of an unknown gene on 9q34

Genes Chromosomes and Cancer

Volumn 20, Issue 2, 1997, Pages 113-119

  Wlodarska, Iwona ^a   Pittaluga, Stefania ^a   Stul, Michel ^a   Martiat, Philippe ^b   Dierlamm, Judith ^a   Michaux, Lucienne ^b   De Wolf Peeters, Chris ^a   Cassiman, Jean Jacques ^a   Mecucci, Cristina ^c   Van Den Berghe, Herman ^a,d  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

^c UNIVERSITY OF PERUGIA   (Italy)

^d CENTER FOR HUMAN GENETICS   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LAMBDA CHAIN; ONCOPROTEIN;

ADULT; ARTICLE; CASE REPORT; CHROMOSOME 9P; CHROMOSOME TRANSLOCATION 9; CHRONIC MYELOID LEUKEMIA; FLUORESCENCE IN SITU HYBRIDIZATION; FOLLICULAR LYMPHOMA; GENE REARRANGEMENT; HUMAN; HUMAN TISSUE; MALE; NONHODGKIN LYMPHOMA; ONCOGENE; ONCOGENE MYC; PHILADELPHIA 1 CHROMOSOME; PRIORITY JOURNAL;

BLOTTING, SOUTHERN; CHROMOSOME BANDING; CHROMOSOMES, HUMAN, PAIR 22; CHROMOSOMES, HUMAN, PAIR 9; GENE REARRANGEMENT; GENES, ABL; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LAMBDA-CHAINS; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; LYMPHOMA, FOLLICULAR; MALE; MIDDLE AGED; MULTIGENE FAMILY; POLYMERASE CHAIN REACTION; TRANSLOCATION, GENETIC;

EID: 0030982598     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2264(199710)20:2<113::AID-GCC2>3.0.CO;2-6     Document Type: Article

References (40)

1. Arenson E, Pasut B, Carstens B, McGravan L (1989) Translocation (2;9) associated with poor outcome of childhood lymphoblastic lymphoma. Proc Annu Meet Am Soc Clin Oncol 8:1091.
2. Arnoldus EPJ, Wiegant J, Noodermeer IA, Wessels JW, Beverstock GC, Grosveld GC, van der Ploeg H, Raap AK (1990) Detection of the Philadelphia chromosome in interphase nuclei. Cytogenet Cell Genet 54:108-111.
3. Barbieri D, Michaux JL, Bosly A, Van Hove W, Noens L, Drochmans A, Louwagie A, Tricot G, Boogaerts M, Vermaelen K, Van den Berghe H (1984) Cytogenetic evaluation of bone marrow involvement in non-Hodgkin's lymphomas. A survey of 94 cases. Haematologica 69:285-296.
4. Cheng G, McLeish W, Huebsch L, Drouin J, van der Jagt R, Tittley P, Markman S, Tin Aye M, Burns B (1992) Rearrangement of BCR genes in malignant lymphoma. Leukemia 6:553-555.
5. Cleary ML (1991) Oncogenic conversion of transcription factors by chromosomal translocations. Cell 66:619-622.
6. Combriato G, Klobeck H-G (1991) Vλ and Cλ gene segments of the human immunoglobulin λ light chain locus are separated by 14 kb and rearrange by a deletion mechanism. Eur J Immunol 21:1513-1522.
7. Croce CM (1993) Molecular biology of lymphomas. Semin Oncol 20:31-46.
8. de Jong D, Voetdijk BMH, Beverstock GC, van Ommen GJB, Willemze R, Kluin PM (1988) Activation of the c-myc oncogene in a precursor-B-cell blast crisis of follicular lymphoma, presenting as composite lymphoma. N Engl J Med 318:1373-1378.
9. Dierlamm J, Wlodarska I, Michaux L, La Starza R, Zeller W, Mecucci C, Van den Berghe H (1996) Successful use of the same slide for consecutive fluorescence in situ hybridization (FISH) experiments. Genes Chromosomes Cancer 16:261-264.
10. Dyer MJS, Lillington DM, Bastard C, Tilly H, Lens D, Heward JM, Stranks G, Morilla R, Monard S, Guglielmi P, Kluin-Nelemans JC, Hagemeijer A, Young BD, Catovsky D (1996) Concurrent activation of MYC and BCL2 in B cell non-Hodgkin lymphoma cell lines by translocation of both oncogenes to the same immunoglobulin heavy chain locus. Leukemia 10:1198-1208.
11. Fujii H, Yashige H, Misawa S, Tanaka S, Urata Y, Matuyama F (1990) Ph chromosome in a patient with nonleukemic non-Hodgkin B-cell lymphoma. Am J Hematol 35:213-215.
12. Heisterkamp N, Groffen J (1991) Molecular insights into the Philadelphia translocation. Hematol Pathol 5:1-10.
13. ISCN (1995) Guidelines for Cancer Cytogenetics. Supplement to an International System for Human Cytogenetic Nomenclature. Mitelman F (ed). Basel: Karger.
14. Juliusson G, Friberg K, Gahrton G (1985) Ph chromosome and B-cell malignancy-associated chromosomal aberrations in nonleukaemic immunoblastic B-cell lymphoma. Acta Haematol 74:171-174.
15. Kaneko Y, Variakojis D, Kluskens L, Rowley JD (1982) Lymphoblastic lymphoma: Cytogenetic, pathologic, and immunologic studies. Int J Cancer 30:273-279.
16. Kaneko Y, Frizzera G, Maseki N, Sakurai M, Komada Y, Sakurai M, Hiyoshi Y, Nakadate H, Takeda T (1988) A novel translocation t(9;17)(q34;q23) in aggressive childhood lymphoblastic lymphoma. Leukemia 2:745-748.
17. Karsan A, Gascoyne RD, Coupland RW, Shepherd JD, Phillips GL, Horsman DE (1993) Combination of t(14;18) and a Burkitt's type translocation in B-cell malignancies. Leukemia Lymphoma 10:433-441.
18. Kawasaki K, Minoshima S, Schooler K, Kudoh J, Asakawa S, de Jong PJ, Shimizu N (1995) The organization of the human immunoglobulin λ gene locus. Genome Res 5:125-135.
19. Larsson C, Lardelli M, White I, Lendahl U (1994) The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocation. Genomics 24:253-258.
20. Lee JT, Innes DJ, Williams ME (1989) Sequential bcl-2 and c-myc oncogene rearrangements associated with the clinical transformation of non-Hodgkin's lymphoma. J Clin Invest 84:1454-1459.
21. Martiat P, Maisin D, Philippe M, Ferrant A, Michaux JL, Cassiman JJ, Van den Berghe H, Sokal G (1990) Detection of residual bcr/abl transcripts in chronic myeloid leukaemia patients in complete remission using the polymerase chain reaction and nested primers. Br J Haematol 75:355-358.
22. Maseki N, Kaneko Y, Sakurai M, Kurihara M, Sampi K, Shimamura K, Takayama S (1987) Chromosome abnormalities in malignant lymphoma in patients from Saitama. Cancer Res 47:6767-6775.
23. Mitani K, Sato Y, Tojo A, Ishikawa F, Kobayashi Y, Miura Y, Miyazono K, Urabe A, Takaku F (1990) Philadelphia chromosome positive B-cell type malignant lymphoma expressing an aberrant 190 kDa bcr-abl protein. Br J Haematol 76:221-225.
24. Mitelman F (1994) Catalog of Chromosome Aberrations in Cancer, 5th Ed. New York: Wiley-Liss, Inc.
25. Morrow B, Goldberg R, Carlson C, Das Gupta R, Sirotkin H, Collins J, Dunham I, O'Donnell H, Scambler P, Shprintzen R, Kucherlapati R (1995) Molecular definition of the 22q11 deletions in velo-cardio-facial syndrome. Am J Hum Genet 56:1391-1403.
26. Nordenson I, Lenner P, Roos G (1983) Patient with B-cell neoplasia (immunoblastic sarcoma) and the Philadelphia chromosome. Cancer Genet Cytogenet 9:37-44.
27. Offit K, Jhanwar SC, Ladanyi M, Filippa DA, Chaganti RSK (1991) Cytogenctic analysis of 434 consecutively ascertained specimens of non-Hodgkin's lymphoma: Correlations between recurrent aberrations, histology, and exposure to cytotoxic treatment. Genes Chromosomes Cancer 3:189-201.
28. Offit K, Parsa NZ, Jhanwar SC, Filippa D, Wachtel M, Chaganti RSK (1993) Clusters of chromosome 9 aberrations are associated with clinico-pathologic subsets of non-Hodgkin's lymphoma. Genes Chromosomes Cancer 7:1-7.
29. Palka G, Fioritoni G, Geraci L, Guanciali-Franchi P, Peca S, Mosca L, Calabrese G (1986) Philadelphia (Ph), 14q+ and 1q+ chromosomes in immunoblastic phase (Richter's syndrome) in a patient with T chronic lymphocytic leukaemia. Haematologica 71:221-224.
30. Rabbitts TH (1994) Chromosomal translocations in human cancer. Nature 372:143-149.
31. Sandberg AA (1990) The Philadelphia chromosome. In: The Chromosomes in Human Cancer and Leukemia, 2nd Ed. New York: Elsevier, pp 427-455.
32. Sun T, Susin M, Koduru P, Coffey EJ, Dittmar K, Weiss R, Gop J, Brody J (1991) Extramedullary blast crisis in chronic myelogenous leukemia. Demonstration of T-cell lineage and Philadelphia chromosome in a paraspinal tumor. Cancer 68:605-610.
33. Terjanian T, Blick MB, Shtalrid M, Manning JT, Trujillo JM, Cabanillas F (1989) Philadelphia chromosome without breakpoint cluster region rearrangement in a case of Lennert's lymphoma of suppressor phenotype. Hematol Oncol 7:189-194.
34. Thangavelu M, Olopade O, Beckman E, Vardiman JW, Larson RA, McKeithan TW, Le Beau MM, Rowley JD (1990) Clinical, morphologic, and cytogenetic characteristics of patients with lymphoid malignancies characterized by both t(14;18)(q32;q21) and t(8;14)(q24;q32) or t(8;22)(q24;q11). Genes Chromosomes Cancer 2:147-158.
35. Tittley P, Trempe JM, van der Jagt R, Drouin J, Huebsch L, McLeish B, Cheng G (1993) Occurrence of T-cell lymphoma in a patient with Philadelphia chromosome-positive chronic myelogenous leukemia with rearrangements of BCR and TCR-β genes in the lymph node. Am J Hematol 42:229-230.
36. Tkachuk DC, Westbrook CA, Andreeff M, Donlon TA, Cleary ML, Suryanarayan K, Homge M, Redner A, Gray J, Pinkel D (1990) Detection of bcr-abl fusion in chronic myelogenous leukemia by in situ hybridisation. Science 250:559-562.
37. Van den Berghe H, Louwagie A, Broeckaert-Van Orshoven A, David G, Verwilghen R, Michaux JL, Sokal G (1979) Philadelphia chromosome in human multiple myeloma. J Natl Cancer Inst 63:11-16.
38. von Lindern M, Fornerod M, van Baal S, Jaegle M, de Wit T, Grosveld G (1992) The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA. Mol Cell Biol 12:1687-1697.
39. Wlodarska I, Mecucci C, De Wolf-Peeters C, Thomas J, Vandenberghe E, Yan den Berghe H (1991) Two translocations: A follicular variant 2;18 and a Burkitt 8;14 in a small non cleaved non Hodgkin's lymphoma. Leukemia Lymphoma 5:65-69.
40. Yunis JJ, Oken MM, Theologides A, Howe RB, Kaplan ME (1984) Recurrent chromosomal defects are found in most patients with non-Hodgkin's lymphoma. Cancer Genet Cytogenet 13:17-28.