Cyclosporin A, FK506 and rapamycin produce multiple, temporally distinct, effects on memory following single-trial, passive avoidance training in the chick

Brain Research

Volumn 927, Issue 2, 2002, Pages 180-194

  Bennett, Pauleen C ^a   Schmidt, Lisa ^a   Lawen, Alfons ^a   Moutsoulas, Penny ^a   Ng, Kim T ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Calcineurin; Chick; Cyclosporin A; FK506; Learning and memory; Peptidyl prolyl cis trans isomerases; PP2B; Protein phosphatase; Rapamycin

Indexed keywords

CALCINEURIN; CARRIER PROTEIN; CYCLOPHILIN; CYCLOSPORIN A; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATASE; RAPAMYCIN; TACROLIMUS;

AMNESIA; ANIMAL EXPERIMENT; ARTICLE; AVOIDANCE BEHAVIOR; CHICKEN; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFECT; ENZYME INHIBITION; INFORMATION RETRIEVAL; LONG TERM MEMORY; NONHUMAN; PASSIVE AVOIDANCE; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

ANIMALS; ANIMALS, NEWBORN; AVOIDANCE LEARNING; CALCINEURIN; CHICKENS; CYCLOSPORINE; DISCRIMINATION LEARNING; DOSE-RESPONSE RELATIONSHIP, DRUG; IMMUNOSUPPRESSIVE AGENTS; INJECTIONS, INTRAVENTRICULAR; MALE; MEMORY; SIROLIMUS; TACROLIMUS;

EID: 0037081374     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)03353-4     Document Type: Article

References (96)

1. Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampus-based long-term memory
2. Immunopharmacology of rapamycin
3. The continguity of rat and chick multiphasic memory-consolidation models
4. Effects of hypoxia on memory consolidation: Implications for a multistage model of memory
5. Left and right hemisphere memory traces: Their formation and fate. Evidence from events during memory formation in the chick
6. Effects of early experience on c-fos expression in the chick forebrain
7. Learning-induced increase in immediate early gene messenger RNA in the chick forebrain
8. Paired helical filament-like phosphorylation of tau, deposition of β/A4-amyloid and memory impairment in rat induced by chronic inhibition of phosphatase 1 and 2A
9. Protein phosphatase 1-deficient mutant Drosophila is affected in habituation and associative learning
10. The MAPK cascade is required for mammalian associative learning
11. Peptidyl-prolyl-cis/trans-isomerase activity may be necessary for memory formation
12. Cyclosporin A, an inhibitor of calcineurin, impairs memory formation in day-old chicks
13. Concentration-dependent effects of protein phosphatase (PP) inhibitors implicate PP1 and PP2A in different stages of memory formation
14. Involvement of hippocampal cAMP/cAMP-dependent protein kinase signaling pathways in a late memory consolidation phase of aversively motivated learning in rats
15. Further evidence for the involvement of a hippocampal cGMP/cGMP-dependent protein kinase cascade in memory consolidation
16. A synaptic model of memory: Long-term potentiation in the hippocampus
17. Chronic administration of cyclosporine A does not impair memory retention in rats
18. Three-dimensional structure and actions of immunosuppressants and their immunophilins
19. Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein
20. Hormesis: U-shaped dose responses and their centrality in toxicology
21. Immunophilin FK506 binding protein associated with inositol 1,4,5-triphosphate receptor modulates calcium flux
22. Dissection of memory formation: From behavioral pharmacology to molecular genetics
23. Dephosphorylation of phosphopeptides by calcineurin (protein phosphatase 2B)
24. Gene discovery in Drosophila: New insights for learning and memory
25. Mechanism of action of the immunosuppressant rapamycin
26. Inhibition of guanylate cyclase and protein kinase G impairs retention for the passive avoidance task in the day-old chick
27. Peptidly-prolyl-cis/trans isomerases and their effectors
28. Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins
29. Cyclosporins. Structure-activity relationships
30. Identification of the multidrug resistance-related P-glycoprotein as a cyclosporine binding protein
31. Transient hypoxic-amnesia: Evidence for a triphasic memory-consolidating mechanism with parallel processing
32. Memory consolidation: Further evidence for the four-phase model from the time-courses of diethyldithiocarbamate and ethacrynic acid amnesias
33. Immunophilins in protein folding and immunosuppression
34. Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A
35. Peptidylproline cis/trans isomerases
36. A novel intermediate stage in the transition between short- and long-term facilitation in the sensory to motor neuron synapse of aplysia
37. Counteractive effects of norepinephrine and amphetamine on quabain-induced amnesia
38. FK506 and the role of immunophilins in nerve regeneration
39. Calcineurin: Not just a simple protein phosphatase
40. A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase
41. Substrate specificities of the peptidyl prolyl cis-trans isomerase activities of cyclophilin and FK-506 binding protein: Evidence for the existence of a family of distinct enzymes
42. Immunophilins in the brain. FKBP ligands: Novel strategies for the treatment of neurodegenerative diseases
43. Abnormally phosphorylated tau protein in Alzheimer's disease: Heterogeneity of individual regional distribution and relationship to clinical severity
44. Learning, memory and the brain
45. Antisense DNA against calcineurin facilitates memory in contextual fear conditioning by lowering the threshold for hippocampal long-term potentiation induction
46. A facilitatory effect on the induction of long-term potentiation in vivo by chronic administration of antisense oligodeoxynucleotides against catalytic subunits of calcineurin
47. Memory formation: The sequence of biochemical events in the hippocampus and its connection to activity in other brain structures
48. Separate mechanisms for short- and long-term memory
49. Conductance changes, an electrogenic pump and the hyperpolarization of leech neurones following impulses
50. 2+-release channels from cardiac muscle
51. Structure-function relationships in the FK506-binding protein (FKBP) family of peptidylprolyl cis-trans isomerases
52. Biosynthesis and mechanism of action of cyclosporins
53. The CaM kinase II hypothesis for the storage of synaptic memory
54. What maintains memories?
55. Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity
56. Complementary DNA encoding the human T-cell FK506-binding protein, a peptidylprolyl cis-trans isomerase distinct from cyclophilin
57. Inducible and reversible enhancement of learning, memory, and long-term potentiation by genetic inhibition of calcineurin
58. Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory
59. Cellular functions of immunophilins
60. In search of cellular mechanisms of memory
61. The actions of cyclosporin A and FK506 suggest a novel step in the activation of T lymphocytes
62. Dynamics of induction and expression of long-term synaptic facilitation in Aplysia
63. Control of memory formation through regulated expression of a CaMKII transgene
64. Protein kinases: Which one is the memory molecule?
65. Mechanism of action of rapamycin (Sirolimus Rapamune)
66. An essential role for protein phosphatases in hippocampal long-term depression
67. Interactive contributions of intracellular calcium and protein phosphatases to massed-trials learning deficits in Hermissenda
68. A biological model for memory formation
69. Molecular mechanisms of memory formation
70. Training induced dendritic spine density changes are specifically related to memory formation processes in the chick Gallus domesticus
71. Changes in the number and structure of dendritic spines 25 h after passive avoidance training in the domestic chick, Gallus domesticus
72. Memory stages and brain asymmetry in chick learning
73. Brain protein serine/threonine phosphatases
74. Cyclophilin 20 is involved in mitochondrial protein folding in cooperation with molecular chaperones Hsp70 and Hsp60
75. If phosphatases go up, memory goes down
76. Cellular correlates of stages of memory formation in the chick following passive avoidance training
77. SDZ NIM 811
78. Short-term, intermediate-term, and long-term memories
79. Identification of the multidrug resistance-related membrane glycoprotein as an acceptor for cyclosporine
80. Neural roles of immunophilins and their ligands
81. Activity-dependent induction of tonic calcineurin activity mediates a rapid developmental downregulation of NMDA receptor currents
82. Immunophilins in the nervous system
83. Neural actions of immunophilin ligands
84. + channel is modulated by FK506 and rapamycin
85. New immunosuppressive drugs: Mechanistic insights and potential therapeutic advances
86. An inhibitor for calcineurin, FK506, blocks induction of long-term depression in rat visual cortex
87. 4]Cyclosporin, a novel natural cyclosporin with anti-HIV activity: A structural elucidation, biosynthesis and biological properties
88. Cyclosporine A affects open field behavior in DA rats
89. Inhibition of phosphatase 2B prevents expression of hippocampal long-term potentiation
90. Genetic and pharmacological evidence for a novel, intermediate phase of long-term potentiation suppressed by calcineurin
91. Apoptosis induced by inhibitors of the plasma membrane NADH-oxidase involves Bcl-2 and calcineurin
92. The impairment of long-term memory formation by the phosphatase inhibitor okadaic acid
93. 2+/calmodulin-dependent protein kinase in memory formation in day-old chicks
94. Inhibition of intermediate-term memory following passive avoidance training in neonate chicks by a presynaptic cholinergic blocker
95. A selective role of calcineurin aα in synaptic depotentiation in hippocampus