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Volumn 43, Issue 11, 2002, Pages 2063-2067

Synthesis, Fe(II)-induced degradation, and antimalarial activities of 1,5-diaryl-6,7-dioxabicyclo[3.2.2]nonanes: Direct evidence for nucleophilic O-1,2-aryl shifts

(5) Kamata, Masaki a Ohta, Motoko a Komatsu, Ken Ichi a Kim, Hye Sook b Wataya, Yusuke b

a NIIGATA UNIVERSITY (Japan)

b OKAYAMA UNIVERSITY (Japan)

Author keywords

1,5 diaryl 6,7 dioxabicyclo 3.2.2 nonanes; Antimalarial activity; Cyclic peroxides; FeBr2; Fragmentation; O 1,2 aryl shift; Reaction mechanism; Rearrangement

Indexed keywords

1 (4 METHOXYPHENYL)OXY 5 (4 METHOXYPHENYL) 8 OXABICYCLO[3.2.1]OCTANE; 1,5 BIS(4 FLUOROBENZYL) 6,7 DIOXABICYCLO[3.2.2]NONANE; 1,5 BIS(4 METHOXYBENZYL) 6,7 DIOXABICYCLO[3.2.2]NONANE; 1,5 BIS(4 METHYLBENZYL) 6,7 DIOXABICYCLO[3.2.2]NONANE; 1,5 DIPHENYL 6,7 DIOXABICYCLO[3.2.2]NONANE; ANTIMALARIAL AGENT; BICYCLO[3.2.1]OCTANE DERIVATIVE; BROMIDE; IRON; LEWIS ACID; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; DEGRADATION; DRUG SCREENING; DRUG SYNTHESIS; ELECTRON TRANSPORT; IN VITRO STUDY; METHODOLOGY; OXYGENATION; PHOTON;

EID: 0037060948 PISSN: 00404039 EISSN: None Source Type: Journal
DOI: 10.1016/S0040-4039(02)00166-1 Document Type: Article

Times cited : (22)

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