Mutations in the S4-H2 loop of eIF4E which increase the affinity for m7GTP

FEBS Letters

Volumn 516, Issue 1-3, 2002, Pages 9-14

  Spivak Kroizman, Taly ^a   Friedland, Diana E ^b   De Staercke, Christine ^a   Gernert, Kim M ^a   Goss, Dixie J ^b   Hagedorn, Curt H ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

Eukaryotic initiation factor 4E; M7GTP; MRNA cap; RNA binding protein; Translation

Indexed keywords

8 AZIDOGUANOSINE TRIPHOSPHATE; GUANOSINE DERIVATIVE; GUANOSINE TRIPHOSPHATE; INITIATION FACTOR 4E; LYSINE; MESSENGER RNA; NUCLEOTIDE; PHOSPHORUS 32; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CANCER CELL; CONTROLLED STUDY; CORRELATION ANALYSIS; EPITHELIUM CELL; HUMAN; HUMAN CELL; METASTASIS; MUTAGENESIS; MUTATION; PHENOTYPE; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; RNA CAPPING; RNA PURIFICATION;

ANIMALS; BINDING SITES; EUKARYOTIC INITIATION FACTOR-4E; HUMANS; KINETICS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PEPTIDE INITIATION FACTORS; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; RNA CAP ANALOGS; RNA CAPS; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

EUKARYOTA;

EID: 0037051955     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(02)02445-6     Document Type: Article

References (36)