Translational silencing of ceruloplasmin requires the essential elements of mRNA circularization: Poly(A) tail, poly(A)-binding protein and eukaryotic translation initiation factor 4G

Molecular and Cellular Biology

Volumn 21, Issue 19, 2001, Pages 6440-6449

  Mazumder, B ^a   Seshadri, V ^a   Imataka, H ^a   Sonenberg, N ^a   Fox, P L ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CERULOPLASMIN; GAMMA INTERFERON; INITIATION FACTOR 4G; LUCIFERASE; MESSENGER RNA; POLYADENYLATED RNA; PROTEIN ANTIBODY;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; CHIMERA; CONTROLLED STUDY; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RABBIT; REPORTER GENE; RETICULOCYTE LYSATE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA BINDING; RNA TRANSLATION; TRANSLATION INITIATION; TRANSLATION REGULATION;

NON-PROGRAMMATIC;

3' UNTRANSLATED REGIONS; ANIMALS; CERULOPLASMIN; EUKARYOTIC INITIATION FACTOR-4G; GENE SILENCING; HUMANS; INTERFERON TYPE II; MODELS, GENETIC; PEPTIDE INITIATION FACTORS; POLY(A)-BINDING PROTEINS; PROTEIN BIOSYNTHESIS; RABBITS; RNA; RNA, MESSENGER; RNA-BINDING PROTEINS; U937 CELLS;

EID: 0034811090     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.19.6440-6449.2001     Document Type: Article

References (54)

1. The MEF2A 3′ untranslated region functions as a cis-acting translational repressor
2. Biochemical characterisation of cap-poly(A) synergy in rabbit reticulocyte lysates: The eIF4G-PABP interaction increases the functional affinity of eIF4E for the capped mRNA 5′-end
3. The multiple RNA-binding domains of the mRNA poly(A)-binding protein have different RNA-binding activities
4. Fog-2, a novel F-box containing protein, associates with the GLD-I RNA binding protein and directs male sex determination in the C. elegans hermaphrodite germline
5. Mechanism and regulation of mRNA polyadenylation
6. X-ray structure of the human hyperplastic discs protein: An ortholog of the C-terminal domain of poly(A)-binding protein
7. Participation of the human p53 3′-UTR in translational repression and activation following γ-irradiation
8. Translational control of dosage compensation in Drosophila by sex-lethal: Cooperative silencing via the 5′ and 3′ UTRs of msl-2 mRNA is independent of the poly(A) tail
9. eIF4 initiation factors: Effectors of mRNA recruitment to ribosomes and regulators of translation
10. Transcriptional regulation of ceruloplasmin gene expression during inflammation
11. Multiple portions of poly(A)-binding protein stimulate translation in vivo
12. A mechanism for translationally coupled mRNA turnover: Interaction between the poly(A) tail and a c-fos RNA coding determinant via a protein complex
13. The mRNA poly(A)- binding protein: Localization, abundance and RNA-binding specificity
14. Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux
15. Identification of a GA-rich sequence as a protein-binding site in the 3′-untranslated region of chicken elastin mRNA with a potential role in the developmental regulation of elastin mRNA stability
16. The eukaryotic polypeptide chain releasing factor (eRF3/GSPT) carrying the translation termination signal to the 3′-poly(A) tail of mRNA. Direct association of erf3/GSPT with polyadenylate-binding protein
17. A newly identified N-terminal amino acid sequence of human eIF4G binds poly(A)-binding protein and functions in poly(A)-dependent translation
18. Control of the translational efficiency of β-FI-ATPase mRNA depends on the regulation of a protein that binds the 3′ untranslated region of the mRNA
19. The STAR protein, GLD-1, is a translational regulator of sexual identity in Caenorhabditis elegans
20. Dual interactions of the translational repressor Paip2 with the poly(A) binding protein
21. Regulating the fate of mRNA: The control of cellular iron metabolism
22. Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA
23. Pbplp, a factor interacting with Saccharomyces cerevisiae poly(A)-binding protein, regulates polyadenylation
24. Origins and targets of translational control
25. Delayed translational silencing of ceruloplasmin transcript in gamma interferon-activated U937 monocytic cells: Role of 3′ untranslated region
26. Induction of ceruloplasmin synthesis by IFN-γ in human monocytic cells
27. A GG nucleotide sequence of the 3′ untranslated region of amyloid precursor protein mRNA plays a key role in the regulation of translation and the binding of proteins
28. Cap-poly(A) synergy in mammalian cell-free extracts.Investigation of the requirements for poly(A)-mediated stimulation of translation initiation
29. Familial apoceruloplasmin deficiency associated with blepharospasm and retinal degeneration
30. IRP-1 binding to ferritin mRNA prevents the recruitment of the small ribosomal subunit by the cap-binding complex cIF4F
31. The possible significance of the ferrous oxidase activity of ceruloplasmin in normal human serum
32. Lipoxygenase mRNA silencing in erythroid differentiation: The 3′UTR regulator, complex controls 60S ribosomal subunit joining
33. mRNA silencing in erythroid differentiation: HnRNP K and hnRNP El regulate 15-lipoxygenase translation from the 3′ end
34. Translation of 15-lipoxygenase mRNA is inhibited by a protein that binds to a repeated sequence in the 3′ untranslated region
35. Stress-activated protein kinases (JNK and p38/HOG) are essential for vascular endothelial growth factor mRNA stability
36. TIA-1 is a translational silencer that selectively regulates the expression of TNF-α
37. From factor to mechanism: Translation and translational control in eukaryotes
38. Ribosome concentration contributes to discrimination against poly(A)-mRNA during translation initiation in Saccharomyces cerevisiae
39. Dynamics of poly(A) addition and removal during development
40. Complex contribution of the 3κ-untranslated region to the expressional regulation of the human inducible nitric-oxide synthase gene. Involvement of the RNA-binding protein HuR
41. Binding of a cytosolic protein to the iron-responsive element of human ferritin messenger RNA
42. Ceruloplasmin
43. Starting at the beginning, middle and end: Translation initiation in eukaryotes
44. Eukaryotic translation initiation: There are (at least) two sides to every story
45. Regulation of translation by specific protein/mRNA interactions
46. Translation of vascular endothelial growth factor mRNA by internal ribosome entry: Implications for translation under hypoxia
47. The intracellular localization of messenger RNAs
48. Association of the yeast poly(A) tail binding protein with translation initiation factor eIF-4G
49. Translation initiation factor eIF4G mediates in vitro poly(A) tail-dependent translation
50. Rapid deadenylation and poly(A)-dependent translational repression mediated by the Caenorhabditis elegans tra-2 3′ untranslated region in Xenopus embryos
51. Interaction of eIF4G with poly(A)-binding protein stimulates translation and is critical for Xenopus oocyte maturation
52. Circularization of mRNA by eukaryotic translation initiation factors
53. Life and death in the cytoplasm: Messages from the 3′ end
54. Translational control of developmental decisions