A rostro-caudal dissociation in the dorsal and ventral striatum of the juvenile SHR suggests an anterior hypo- and a posterior hyperfunctioning mesocorticolimbic system

Behavioural Brain Research

Volumn 130, Issue 1-2, 2002, Pages 171-179

  Papa, M ^a   Diewald, L ^b   Carey, M P ^b   Esposito, F J ^b   Gironi Carnevale, U A ^b   Sadile, A G ^b  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b Laboratory of Neurophysiology   (Italy)

Author keywords

ADHD; Autoradiography; c FOS; CaMKII; Dopamine receptors; Dorsal striatum; Frontal cortex; Genetic models; Immunocytochemistry; Postnatal handling; Quinpirole binding; Raclopride binding; SCH 23390; SHR rat; Ventral striatum

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; AUTORECEPTOR; CANNABINOID; DOPAMINE 1 RECEPTOR; DOPAMINE 5 RECEPTOR; METHYLPHENIDATE; N (4 HYDROXYPHENYL)ARACHIDONAMIDE; PROTEIN KINASE (CALCIUM,CALMODULIN); TRANSCRIPTION FACTOR;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ATTENTION; ATTENTION DEFICIT DISORDER; AUTORADIOGRAPHY; BINDING SITE; CONFERENCE PAPER; CONTROLLED STUDY; CORPUS STRIATUM; DISSOCIATION; DOWN REGULATION; EMOTIONALITY; FOREBRAIN; GLOBUS PALLIDUS; IMMUNOHISTOCHEMISTRY; LIMBIC SYSTEM; MALE; MOTIVATION; NEGATIVE FEEDBACK; NONHUMAN; NUCLEUS ACCUMBENS; OLFACTORY BULB; ONCOGENE C FOS; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; RECEPTOR DENSITY; RECEPTOR UPREGULATION; SYMPTOM; TARGET CELL; VENTRAL TEGMENTUM;

ANIMALS; AUTORADIOGRAPHY; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CEREBRAL CORTEX; DOPAMINE; ENDOCANNABINOIDS; IMMUNOHISTOCHEMISTRY; LIMBIC SYSTEM; NEOSTRIATUM; PERFUSION; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-JUN; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; TRANSCRIPTION FACTORS;

EID: 0037051131     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-4328(01)00421-1     Document Type: Conference Paper

References (37)

1. A targeted mutation of the D3 dopamine receptor gene is associated with hyperactivity in mice
2. Changes in the second messenger cyclic AMP during development may underlie motoric symptoms in ADHD
3. Sex differences in Dopamine receptors and their relevance to ADHD
4. Non selective attention in a rat model of hyperactivity and attention deficit: Subchronic methylphenidate and nitric oxide synthesis inhibitor treatment
5. Non-selective attention and nitric oxide in putative animal models of Attention-Deficit Hyperactivity Disorder
6. Reversal of dopamine D2-receptor responses by an anandamide trasport inhibitor
7. The contribution of comparative studies in inbred strains of mice to the understanding of the hyperactive phenotype
8. Differential distribution, affinity and plasticity of dopamine D- 1 and D-2 receptors in the target sites of the mesolimbic system in an animal model of ADHD
9. Differencial response of dopamine D-3 autoreceptors to subchronic methylphenidate treatment im anterior forebrain sites of an animal model of hyperactivity and attention deficits
10. Dopamine activation of endogenous cannabiniod signaling in dorsal striatum
11. The tonic/phasic model of dopamine system regulation: Its relevance for understanding how stimulant abuse can alter basal ganglia function
12. Endocannabinoids modulate activity and non-selective attention in two animal models of ADHD
13. Inhibition of neuronal Nitric Oxide synthesis by 7-nitroindazole reduces hyperactivity and increases non-selective attention in the Naples High Excitability rat model of ADHD: An evidence in favour of an hyperfunctioning dopamine system
14. Organization of the efferent projections of the nucleus accumbens to pallidal, hypothalamic and mesencephalic structures: A tracing and immunohistochemical study in the cat
15. The distribution of the projection from the hippocampal formation to the nucleus accumbens in the rat: An anterograde- and retrograde-horseradish peroxidase study
16. Up-regulation of dopamine receptors in the brain of the spontaneously hypertensive rat: An autoradiographic analysis
17. 3H]spiperone binding to rat brain regions
18. The organization of the projection from the cerebral cortex to the striatum of the rat
19. Stimulus-transcription coupling in the nervous system: Involvement of the inducible proto-oncogenes fos and jun
20. Reduced CaMKII-positive neurones in the accumbal shell of an animal model of Attention-Deficit Hyperactivity Disorder
21. Remodeling of neural Networks in the anterior forebrain of an animal model of hyperactivity and attention deficit as monitored by molecular imaging probes
22. Differential expression of transcription factors in the accumbens of an animal model of ADHD
23. Arousal systems and attention
24. The nucleus accumbens motor-limbic interface of the spontaneously hypertensive rat as studied in-vitro by the superfusion slice technique
25. Multiple evidence of a segmental defect in the anterior forebrain of an animal model of hyperactivity and attention deficit
26. Behavioral validation of the spontaneously hypertensive rat (SHR) as an animal model of attention-deficit hyperactivity disorder (AD/HD)
27. 2+/calmodulin-dependent protein kinases
28. Methylphenidate elevates resting dopamine which lowers impulse-triggered release of dopamine: A hypothesis
29. Anti-hyperactivity medication: Methylphenidate and amphetamine
30. A network model of catecholamine effects: Gain, signal-to-noise ratio, and behavior
31. Neuropsychopharmacological mechanisms of stimulant drug action in attention-deficit hypractivity disorder: A review and integration
32. Clinical psychopharmacology of AD/HD: Implications for animal models
33. Attention deficit hyperactivity disorder and hyperkynetic disorder
34. Structure and function of dopamine receptors
35. Brain dopamine transporter in spontaneously hypertensive rats
36. An integrative neuroanatomical perspective on some subcortical substrates of adaptive responding with emphasis on the nucleus accumbes