Remodeling of neural networks in the anterior forebrain of an animal model of hyperactivity and attention deficits as monitored by molecular imaging probes

Neuroscience and Biobehavioral Reviews

Volumn 24, Issue 1, 2000, Pages 149-156

  Papa, M ^a   Sellitti, S ^a   Sadile, A G ^b  

^a Laboratory of Neurophysiology   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

c FOS; CaMKII; Correlative analysis; Cytochrome oxidase; Dopamine receptors; SHR line

Indexed keywords

2 DIPROPYLAMINO 7 HYDROXYTETRALIN; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; CYTOCHROME C OXIDASE; DOPAMINE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; KETANSERIN; METHYLPHENIDATE; PROTEIN C FOS; PROTEIN KINASE (CALCIUM,CALMODULIN) II; QUINPIROLE; RACLOPRIDE; RADIOLIGAND; SPIPERONE; TRANSCRIPTION FACTOR;

AMYGDALOID NUCLEUS; ANIMAL MODEL; ANIMAL TISSUE; ATTENTION DEFICIT DISORDER; AUTORADIOGRAPHY; BEHAVIOR; BRAIN REGION; CONFERENCE PAPER; CONTROLLED STUDY; FEMALE; FOREBRAIN; GENE EXPRESSION; HYPERACTIVITY; IMAGE ANALYSIS; IMAGING; IMMUNOCYTOCHEMISTRY; LIGAND BINDING; MALE; MICROCOMPUTER; MODEL; MOLECULAR BIOLOGY; MONITORING; NERVE CELL NETWORK; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BINDING; RESPIRATORY CHAIN; SPONTANEOUSLY HYPERTENSIVE RAT; TECHNIQUE;

ANIMALS; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; AUTORADIOGRAPHY; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; DOPAMINE UPTAKE INHIBITORS; ELECTRON TRANSPORT COMPLEX IV; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; MALE; METHYLPHENIDATE; NERVE NET; PROSENCEPHALON; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RECEPTORS, DOPAMINE;

EID: 0033984190     PISSN: 01497634     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0149-7634(99)00052-4     Document Type: Conference Paper

References (28)

1. Marrocco R.T., Witte E.A., Davidson M.C. Arousal systems. Curr Opin Neurobiol. 4:1994;166-170.
2. Posner M.I., Dehasne S. Attentional networks. Trends Neurosci. 17:1994;75-79.
3. Berger A., Posner M.I. Pathologies of brain attentional networks. Neurosci Biobehav Rev. 24:2000;3-5.
4. Swanson J., Castellanos F.X., Murias M., La Hoste G., Kennedy J. Cognitive neuroscience of attention deficit hyperactivity disorder and hyperkinetic disorder. Curr Opinion Neurobiol. 8:1998;263-271.
5. Aspide R., Fresiello A., Gironi Carnevale U.A., Sadile A.G. Non-selective attention in a rat model of hyperactivity and attention deficit: subchronic dopamine reuptake and nitric oxide synthesis inhibition. Neurosci Biobehav Rev. 1999.
6. Sagvolden T. A behavioral analysis validation of spontaneous hypertensive rat (SHR) as a model of ADHD. Neurosci Biobehav Rev. 24:2000;31-39.
7. Russell V. The nucleus accumbens motor-limbic interface of the spontaneously hypertensive rat (SHR) as studied in-vitro by the superfusion slice technique. Neurosci Biobehav Rev. 24:2000;133-136.
8. Zahm D.S. An integrative perspective on the neuroanatomical substrates of adaptive responding with emphasis on nucleus accumbes subterritories. Neurosci Biobehav Rev. 24:2000;85-105.
9. Carey M.P., Diewald L., Papa M., Gironi Carnevale U.A., Pellicano M.P., Esposito F., Sergeant J.A., Sadile A.G. Differential distribution, affinity and plasticity of dopamine D-1 and D-2 receptors in the target sites of the mesolimbic system in an animal model of ADHD. Behav Brain Res. 94:1998;173-185.
10. Esposito F.J., Gironi Carnevale U.A., Diewald L.M., Carey M.P., Vallone D., Sadile A.G. Differencial response of dopamine D-3 autoreceptors to subchronic methylphenidate treatment in anterior forebrain sites of an animal model of hyperactivity and attention deficits. 1999;25.
11. Papa M., Sagvolden T., Sergeant J.A., Sadile A.G. Reduced CaMKII-positive neurones in the accumbal shell of an animal model of attention-deficit hyperactivity disorder. NeuroReport. 7:1996;3017-3020.
12. Papa M., Sergeant J.A., Sadile A.G. Differential expression of transcription factors in the accumbens of an animal model of ADHD. NeuroReport. 8:1997;1607-1612.
13. Papa M., Sergeant J.A., Sadile A.G. Reduced transduction mechanisms in the anterior accumbal interface of an animal model of attention-deficit hyperactivity disorder. Behav Brain Res. 94:1998;187-195.
14. Sadile A.G. Multiple evidence of a segmental defect in the antenor forebrain of an animal model of hyperactivity and attention deficit. Neurosci Biobehav Rev. 24:2000;161-169.
15. Breggin P.R. Psychostimulants in the treatment of children diagnosed with ADHD: risks and mechanism of action. Risk and safety in medicine. 12:1999;1-48.
16. Solanto M.V. Neuropsychopharmacological mechanisms of stimulant drug action in attention-deficit hyperctivity disorder: a review and integration. Behav Brain Res. 94:1998;127-152.
17. 3H]spiperone binding to rat brain regions. Proc Natl Acad Sci USA. 78:1981;2620-2624.
18. Gonzalez-Lima F., Jones D. Quantitative mapping of cytochrome oxidase activity in the central nervous system of the gerbil: a study with calibrated activity standards and metal-intensified histochemistry. Brain Res. 660:1994;34-49.
19. Edwards A.L. Statistical methods for the behavioral sciences. 1967;Holt (Rinehart & Winston), New York.
20. Grace A.A. The tonic/phasic model of dopamine system regulation: its relevance for understanding how stimulant abuse can alter basal ganglia function. Drug Alcohol Depend. 37:1995;111-129.
21. Grace A.A., Bunney B.S., Moore H., Todd C.L. Dopamine-cell depolarization block as a model for the therapeutic actions of antipsychotic drugs. Trends Neurosci. 20:1997;31-37.
22. Morgan J.I., Curran T. Inducible proto-oncogenes of the nervous system: their contribution to transcription factors and neuroplasticity. Prog Brain Res. 86:1990;287-294.
23. Papa M., Pellicano M.P., Welzl H., Sadile A.G. Distributed changes in c-Fos and c-Jun immunoreactivity in the rat brain associated with arousal and habituation to novelty. Brain Res Bull. 32:1993;509-515.
24. Sadile A.G., Lamberti-D'Mello C., Cerbone A., Amoroso S., Annunziato L., Menna T., Buono C., Giuditta A. Adrenergic receptor systems and unscheduled DNA synthesis in the rat brain. Brain Res Bull. 37:(2):1995;139-148.
25. Pitkanen A., Savander V., LeDoux J.E. Organization of intra-amygdaloid circuitries in the rat: an emerging framework for understanding functions of the amygdala. Trends Neurosci. 20:1997;517-523.
26. Eilam R., Malach R., Segal M. Selective elimination of hypothalamic neurons by grafted hypertension-inducing tissue. J Neurosci. 14:1994;4891-4902.
27. Cada A., Gonzales-Lima F., Rose G., Bennet M. Regional brain effects of sodium azide treatment on cytochrom oxidase: a quantitative histochemical study. Metab Brain Dis. 10:1995;303-320.
28. Papa M., Berger D.F., Sagvolden T., Sergeant J.A., Sadile A.G. A quantitative cytochrome oxidase mapping study, cross-regional and neurobehavioral correlative analyses in the anterior forebrain of an animal model of ADHD. Behav Brain Res. 94:1998;172-211.