Synthesis and anti-platelet evaluation of new tricyclic PAF antagonists, designed as structurally related to hetrazepine class - Web 2086

Journal of the Brazilian Chemical Society

Volumn 7, Issue 5, 1996, Pages 247-256

  De Carvalho, Alcione S ^a   Fraga, Carlos A M ^a,b   Da Silva, Kelli C M ^a   Miranda, Ana L P ^a   Barreiro, Eliezer J ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

Author keywords

Functionalized pyrazolo 3,4 b thieno 2,3 d pyridine system; PAF antagonists; WEB2086 analogues

Indexed keywords

EID: 0030522176     PISSN: 01035053     EISSN: None     Source Type: Journal    
DOI: 10.5935/0103-5053.19960051     Document Type: Article

References (31)

1. Chao, W.; Olson, M. S. Biochem. J. 1993, 292, 617.
2. Benveniste, J.; Henson, P.M.; Cochrane, C.G. J. Exp. Med. 1972, 136, 1356.
3. Vargaftig, B.B.; Lefort, J.; Chignard; Benveniste, J. Eur. J. Pharmacol. 1980, 65, 185.
4. Weber, K.H.; Walther, G.; Harreus, A.; Casals-Stenzel, J.; Muacevic, G.; Troger, W. Japan. Patent 61 176 591 1986,.
5. Casals-Stenzel, J.; Muacevic, G.; Weber, K. H. J. Pharm. Exp. Therapeutics 1987, 241, 974-981.4.
6. Garzone, P.D.; Kroboth, P.D. Clin. Pharmacokinet. 1989, 16, 337.
7. Bures, M.G.; Danaher, E.; DeLazzer, J.; Martin, Y. J. Chem. Inf. Comput. Sci. 1994, 34, 218.
8. Biaggio, F.C.; Barreiro, E.J. J. Heterocyclic Chem. 1989, 26, 725.
9. Freitas, A.C.C.; Barreiro, E.J. J. Heterocyclic Chem. 1992, 29, 407.
10. Fraga, C.A.M.; Barreiro E.J. J. Heterocyclic Chem. 1992, 29, 1667
11. Lima, M.E.F.; Barreiro, E.J. J. Pharm. Sci. 1992, 58, 1219.
12. Silva, E.F.; Barreiro, E.J. J. Braz. Chem. Soc. 1993, 4, 40.
13. Dias, L.R.S.; Alvim, M.J.F.; Freitas, A.C.C.; Barreiro, E.J.; Miranda, A.L.P. Pharmaceutica Acta Helvetiae 1994, 69, 163.
14. Cabral, L.M.; Barreiro, E.J. J. Heterocyclic Chem. 1995, 32, 959.
15. Carvalho, A.S. MSc. Thesis, Instituto de Química, LASSBio; Universidade Federal do Rio de Janeiro, Rio de Janeiro, 1996.
16. Carvalho, A.S.; Fraga, C.A.M.; Barreiro, E.J. J. Heterocyclic Chem. 1996, 33, 309.
17. a) Barreiro, E.J. Rev. Bras. Farm. 1991, 72, 2;
18. b) Barreiro, E.J. ibid., 34.
19. Weber, K.H.; Heuer, H.O. Med. Res. Rev. 1989, 9, 181.
20. Furniss, B.S.; Hannaford, A.J.; Smith, P.W.; Tatchell, A.R. In Vogel's Textbook of Practical Organic Chemistry; Longman Scientific and Technical, London: 1991; p 702.
21. Shriner, R.L.; Fuson, R.C.; Curtin, D.Y.; Morrill, T.C. In Identificação Sistematica dos Compostas Orgânicos; Guanabara Dois: Rio de Janeiro, 1983; p 311.
22. Mathew, A.E.; Mejillano, M.R.; Nath, J.P.; Himes, R.H.; Stella, V.J. J. Med. Chem. 1992, 35, 145.
23. Bare, T.M.; McLaren, C.D.; Campbell, J.B.; Firor, J.W.; Resch, J.F.; Walters, C.P.; Salama, A.I.; Meiners, B.A.; Patel, J.B. J. Med. Chem. 1989, 32, 2561.
24. Murray, W.V.; Hadden, S.K.; Watchter, M.P. J. Heterocyclic Chem. 1990, 27, 1933.
25. Kanth, J.V.B.; Periasamy, M. J. Org. Chem. 1991, 50, 5964.
26. Fraga, C.A.M.; Barreiro, E.J. Synth. Comm. 1995, 25, 1133.
27. Fukushi, H.; Mabuchi, H.; Itoh, K.; Terashita, Z.; Nishikawa, K.; Sugihara, H. Chem. Pharm. Bull. 1994, 42, 541.
28. Wadsworth, W.S.; Emmons, W.D. J. Amer. Chem. Soc. 1961, 55, 1733.
29. Barrow, R.A.; Hemscheidt, T.; Liang, J.; Paik, S. Moore, R.E.; Tius, M.A. J. Am. Chem. Soc. 1995, 117, 2479.
30. Silveira, I.A.F.B.; Paulo, L.G.; Miranda, A.L.P.; Rocha, S.O.; Freitas, A.C.C.; Barreiro, E.J. J. Pharm. Pharmacol. 1993, 45, 646.
31. Born, B.; Cross, M.J. J. Physiol. 1963, 168, 178.