Synthesis of condensed tricyclic pyrazolo[3,4-b]thieno[2,3-d]pyridine and related isostere derivatives

Journal of Heterocyclic Chemistry

Volumn 33, Issue 2, 1996, Pages 309-313

  De Carvalho, Alcione S ^a   Fraga, Carlos A M ^a   Barreiro, Eliezer J ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

PYRAZOLE DERIVATIVE; PYRAZOLO[3,4 B]THIENO[2,3 D]PYRIDINE DERIVATIVE; PYRIDINE DERIVATIVE; THIOPHENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS;

EID: 0029892803     PISSN: 0022152X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jhet.5570330216     Document Type: Article

References (14)

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8. Abstracted in part, from MSc. Thesis of A. S. Carvalho (Instituto de Química-Universidade Federal do Rio de Janeiro), in preparation.
9. Methyl thioglycolate and methyl glycolate were prepared by esterification of the respective carboxylic acids [13] with diazomethane in ethyl ether, and carefully distilled at reduced pressure (10 mm Hg).
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12. Glycine ethyl ester was prepared, in 70% yield, employing the Fisher's esterification [14] of glycine [13], and purified by distillation at reduced pressure (10 mm Hg).
13. Purchased from Aldrich Co., Milwaukee, USA.
14. B. S. Furniss, A. J. Hannaford, P. W. G. Smith and A. R. Tatchell, Vogel's Textbook of Practical Organic Chemistry, Longman Scientific & Technical, London, 1991, p 762.