HemK, a class of protein methyl transferase with similarity to DNA methyl transferases, methylates polypeptide chain release factors, and hemK knockout induces defects in translational termination

Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 3, 2002, Pages 1473-1478

  Nakahigashi, Kenji ^a   Kubo, Naoko ^a   Narita, Shin Ichiro ^a,d   Shimaoka, Takeshi ^a   Goto, Simon ^a   Oshima, Taku ^b,c   Mori, Hirotada ^b,c   Maeda, Maki ^a,b   Wada, Chieko ^a   Inokuchi, Hachiro ^a  

^a KYOTO UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

^d TOKAI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; DNA METHYLTRANSFERASE; MESSENGER RNA; POLYPEPTIDE CHAIN RELEASE FACTOR 2; PROTEIN HEMK; PROTEIN METHYLTRANSFERASE; RELEASING FACTOR; THREONINE; TRANSFER RNA; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANAEROBIC CAPACITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATION; CODON; DNA MICROARRAY; ENZYME ACTIVITY; ESCHERICHIA COLI; GENE EXPRESSION; GENE MUTATION; GENE REPRESSION; GROWTH RETARDATION; KNOCKOUT GENE; NONHUMAN; OXIDATIVE STRESS; PHOTOSENSITIVITY; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN METHYLATION; PROTEIN MOTIF; REACTION ANALYSIS;

AMINO ACID SEQUENCE; ANAEROBIOSIS; BETA-GALACTOSIDASE; BINDING SITES; CLONING, MOLECULAR; CULTURE MEDIA; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE DELETION; GENE EXPRESSION REGULATION, BACTERIAL; KINETICS; METHYLATION; MUTATION, MISSENSE; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PEPTIDE CHAIN TERMINATION, TRANSLATIONAL; PROTEIN METHYLTRANSFERASES; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SUPPRESSION, GENETIC;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0037022398     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.032488499     Document Type: Article

References (36)