Mutations in the highly conserved GGQ motif of class I polypeptide release factors abolish ability of human eRF1 to trigger peptidyl-tRNA hydrolysis

RNA

Volumn 5, Issue 8, 1999, Pages 1014-1020

  Frolova, Ludmila Yu ^a,c,d   Tsivkovskii, Ruslan Yu ^b   Sivolobova, Galina F ^b   Oparina, Nina Yu ^a   Serpinsky, Oleg I ^b   Blinov, Vladimir M ^b   Tatkov, Sergey I ^b   Kisselev, Lev L ^a,c  

^a ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^b STATE RESEARCH CENTER OF VIROLOGY AND BIOTECHNOLOGY VECTOR   (Russian Federation)

^c INSTITUT CURIE   (France)

^d UNIVERSITÉ DE RENNES 1   (France)

Author keywords

Eukaryotes; Prokaryotes; Site directed mutagenesis; Translation termination

Indexed keywords

AMINO ACID; GLYCINE; GUANOSINE TRIPHOSPHATASE; RELEASING FACTOR; TRANSFER RNA;

AMINO ACID SEQUENCE; ARTICLE; ENZYME ACTIVITY; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN SECONDARY STRUCTURE; RIBOSOME; SITE DIRECTED MUTAGENESIS; STOP CODON; TRANSLATION REGULATION;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CONSERVED SEQUENCE; GTP PHOSPHOHYDROLASES; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HUMANS; HYDROLYSIS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE CHAIN TERMINATION, TRANSLATIONAL; PEPTIDE TERMINATION FACTORS; RNA, TRANSFER, AMINO ACYL; SEQUENCE HOMOLOGY, AMINO ACID; TRANS-ACTIVATORS;

EUKARYOTA; PROKARYOTA;

EID: 0032840382     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S135583829999043X     Document Type: Article

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