A novel p53 mutant retained functional activity in lung carcinomas

DNA Repair

Volumn 1, Issue 9, 2002, Pages 755-762

  Ko, Jiunn Liang ^a   Chiao, Ming Chiang ^a   Chang, Shu Lin ^a   Lin, Pinpin ^a   Lin, Jin Ching ^b   Sheu, Gwo Tarng ^a   Lee, Huei ^a  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Functional p53 mutants; MDM2; Prognosis; Transactivation

Indexed keywords

PROTEIN BAX; PROTEIN MDM2; PROTEIN P21; PROTEIN P53; BAX PROTEIN, HUMAN; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; LUCIFERASE; MDM2 PROTEIN, HUMAN; NUCLEAR PROTEIN; ONCOPROTEIN; PRIMER DNA; PROTEIN BCL 2;

ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CONTROLLED STUDY; DNA VECTOR; GENE FUNCTION; GENE MUTATION; GENE P53; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LUNG CARCINOMA; LUNG NON SMALL CELL CANCER; NULL CELL; PRIORITY JOURNAL; PROGNOSIS; TRANSACTIVATION; TUMOR SUPPRESSOR GENE; WILD TYPE; APOPTOSIS; CELL CULTURE; CELL DIVISION; CHEMISTRY; CLONOGENIC ASSAY; COMPARATIVE STUDY; FEMALE; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSCRIPTION; GENETICS; LUNG TUMOR; MALE; METABOLISM; MIDDLE AGED; MUTATION; PATHOLOGY; PHYSIOLOGY; POLYMERASE CHAIN REACTION; PROMOTER REGION; SITE DIRECTED MUTAGENESIS;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, NON-SMALL-CELL LUNG; CELL DIVISION; COLONY-FORMING UNITS ASSAY; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DNA PRIMERS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEMALE; GENES, P53; HUMANS; LUCIFERASES; LUNG NEOPLASMS; MALE; MIDDLE AGED; MUTAGENESIS, SITE-DIRECTED; MUTATION; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; PROGNOSIS; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-MDM2; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0037019596     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1568-7864(02)00094-0     Document Type: Article

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