메뉴 건너뛰기




Volumn 36, Issue 2, 2002, Pages 175-183

Tumor induction in mouse liver: Di-isononyl phthalate acts via peroxisome proliferation

Author keywords

Di isonyl phthalate; Liver tumors; Peroxisomal proliferation

Indexed keywords

PHTHALIC ACID; PHTHALIC ACID DIISONONYL ESTER; UNCLASSIFIED DRUG;

EID: 0036979584     PISSN: 02732300     EISSN: None     Source Type: Journal    
DOI: 10.1006/rtph.2002.1575     Document Type: Article
Times cited : (26)

References (42)
  • 2
    • 0033669473 scopus 로고    scopus 로고
    • Cell proliferation in the liver: A malpractice not to measure the zonal distribution? Comparison of the lobule-dependent zonal measurement method with the common method of randomly distributed measurement fields
    • Bahnemann, R. (2000). Cell proliferation in the liver: A malpractice not to measure the zonal distribution? Comparison of the lobule-dependent zonal measurement method with the common method of randomly distributed measurement fields. Toxicol. Methods 10, 81-97.
    • (2000) Toxicol. Methods , vol.10 , pp. 81-97
    • Bahnemann, R.1
  • 3
    • 0030799471 scopus 로고    scopus 로고
    • Lobule-dependent zonal measurement (LZM) method for the determination of cell proliferation in the liver
    • Bahnemann, R., and Mellert, W. (1997). Lobule-dependent zonal measurement (LZM) method for the determination of cell proliferation in the liver. Exp. Toxicol. Pathol. 49, 189-196.
    • (1997) Exp. Toxicol. Pathol. , vol.49 , pp. 189-196
    • Bahnemann, R.1    Mellert, W.2
  • 4
    • 74049093082 scopus 로고    scopus 로고
    • Gap junctional intercellular communication (GJIC) studies for 5-phthalate monoesters in hepatocytes of four species: Implications for cancer risk assessment
    • Baker, T., Kalimi, G., Lington, A., Isenberg, J., Klaunig, J., and Nikiforov, A. (1996). Gap junctional intercellular communication (GJIC) studies for 5-phthalate monoesters in hepatocytes of four species: Implications for cancer risk assessment. Toxicologist 30, 208.
    • (1996) Toxicologist , vol.30 , pp. 208
    • Baker, T.1    Kalimi, G.2    Lington, A.3    Isenberg, J.4    Klaunig, J.5    Nikiforov, A.6
  • 7
    • 0022994185 scopus 로고
    • Species differences in the response of cultured hepatocytes to phthalate esters
    • Benford, D., Patel, S., Reavy, H., Mitchell, A., and Sarginson, N. (1986). Species differences in the response of cultured hepatocytes to phthalate esters. Food Chem. Toxicol. 24, 799-800.
    • (1986) Food Chem. Toxicol. , vol.24 , pp. 799-800
    • Benford, D.1    Patel, S.2    Reavy, H.3    Mitchell, A.4    Sarginson, N.5
  • 8
    • 0025598930 scopus 로고
    • Toxicological studies on a benzofuran derivative. III. Comparison of peroxisome proliferation in rat and human hepatocytes in primary culture
    • Bichet, N., Cahard, D., Fabre, G., Reandet, B., Gouy, D., and Cano, J. (1990). Toxicological studies on a benzofuran derivative. III. Comparison of peroxisome proliferation in rat and human hepa-tocytes in primary culture. Toxicol. Appl. Pharmacol. 106, 509-517.
    • (1990) Toxicol. Appl. Pharmacol. , vol.106 , pp. 509-517
    • Bichet, N.1    Cahard, D.2    Fabre, G.3    Reandet, B.4    Gouy, D.5    Cano, J.6
  • 9
    • 0002784616 scopus 로고
    • A thirteen week feeding study on diisononyl phthalate (DINP) in rats
    • Bird, M., Kapp, R., Keller, A., and Lington, A. (1986). A thirteen week feeding study on diisononyl phthalate (DINP) in rats. Toxicologist 6, 302.
    • (1986) Toxicologist , vol.6 , pp. 302
    • Bird, M.1    Kapp, R.2    Keller, A.3    Lington, A.4
  • 13
    • 0032867057 scopus 로고    scopus 로고
    • Chronic peroxisome proliferation and hepatomegaly associated with the hepatocellular tumorigenesis of di(2-ethylhexyl)phthalate and the effects of recovery
    • David, R., Moore, M., Cifone, M., Finney, D., and Guest, D. (1999). Chronic peroxisome proliferation and hepatomegaly associated with the hepatocellular tumorigenesis of di(2-ethylhexyl)phthalate and the effects of recovery. Toxicol. Sci. 50, 195-205.
    • (1999) Toxicol. Sci. , vol.50 , pp. 195-205
    • David, R.1    Moore, M.2    Cifone, M.3    Finney, D.4    Guest, D.5
  • 14
    • 0009663357 scopus 로고
    • A multiple comparison procedure for comparing several treatments with a control
    • Dunnett, C. (1955). A multiple comparison procedure for comparing several treatments with a control. J. Am. Stat. Assoc. 50, 1096-1121.
    • (1955) J. Am. Stat. Assoc. , vol.50 , pp. 1096-1121
    • Dunnett, C.1
  • 15
    • 0000080398 scopus 로고
    • New tables for multiple comparisons with a control
    • Dunnett, C. (1964). New tables for multiple comparisons with a control. Biometrics 20, 482-491.
    • (1964) Biometrics , vol.20 , pp. 482-491
    • Dunnett, C.1
  • 16
    • 0022924249 scopus 로고
    • Peroxisome proliferation due to di(2-ethylhexyl) phthalate (DEHP): Species differences and possible mechanisms
    • Elcombe, C., and Mitchell, A. (1986). Peroxisome proliferation due to di(2-ethylhexyl) phthalate (DEHP): Species differences and possible mechanisms. Environ. Health Perspect. 70, 211-219.
    • (1986) Environ. Health Perspect. , vol.70 , pp. 211-219
    • Elcombe, C.1    Mitchell, A.2
  • 17
    • 0014610149 scopus 로고
    • Cytochemical localization of peroxidatic activity of catalase in rat hepatic microbodies (peroxisomes)
    • Fahimi, H. (1969). Cytochemical localization of peroxidatic activity of catalase in rat hepatic microbodies (peroxisomes). J. Cell Biol. 43, 275-288.
    • (1969) J. Cell Biol. , vol.43 , pp. 275-288
    • Fahimi, H.1
  • 19
    • 0033214326 scopus 로고    scopus 로고
    • Comparison of the effects of various peroxisome proliferators on peroxisomal enzyme activities, DNA synthesis, and apoptosis in rat and human hepatocyte cultures
    • Goll, V., Alexandre, E., Viollon-Abadie, C., Nicod, L., Jaeck, D., and Richert, L. (1999). Comparison of the effects of various peroxisome proliferators on peroxisomal enzyme activities, DNA synthesis, and apoptosis in rat and human hepatocyte cultures. Toxicol. Appl. Pharmacol. 160, 21-32.
    • (1999) Toxicol. Appl. Pharmacol. , vol.160 , pp. 21-32
    • Goll, V.1    Alexandre, E.2    Viollon-Abadie, C.3    Nicod, L.4    Jaeck, D.5    Richert, L.6
  • 20
    • 0032832546 scopus 로고    scopus 로고
    • Effects of di-isononyl phthalate (DINP) on peroxisomal markers in the marmoset: DINP is not a peroxisomal proliferator
    • Hall, M., Matthews, A., Webley, L., and Harling, R. (1999). Effects of di-isononyl phthalate (DINP) on peroxisomal markers in the marmoset: DINP is not a peroxisomal proliferator. J. Toxicol. Sci. 24, 237-244.
    • (1999) J. Toxicol. Sci. , vol.24 , pp. 237-244
    • Hall, M.1    Matthews, A.2    Webley, L.3    Harling, R.4
  • 21
    • 0033428565 scopus 로고    scopus 로고
    • Suppression of apoptosis and induction of DNA synthesis in vitro by the phthalate plasticizers monoethylhexylphthalate (MEHP) and diisononylphthalate (DINP): A comparison of rat and human hepatocytes in vitro
    • Hasmall, S., James, N., Macdonald, N., West, D., Chevalier, S., Cosulich, S., and Roberts, R. (1999). Suppression of apoptosis and induction of DNA synthesis in vitro by the phthalate plasticizers monoethylhexylphthalate (MEHP) and diisononylphthalate (DINP): A comparison of rat and human hepatocytes in vitro. Arch. Toxicol. 73, 451-456.
    • (1999) Arch. Toxicol. , vol.73 , pp. 451-456
    • Hasmall, S.1    James, N.2    Macdonald, N.3    West, D.4    Chevalier, S.5    Cosulich, S.6    Roberts, R.7
  • 22
    • 0004016459 scopus 로고
    • Peroxisome proliferation and its role in carcinogenesis: Views and expert opinions of an IARC Working Group, Lyon, 7-11 December, 1994
    • IARC, Lyon
    • International Agency for Research on Cancer (IARC) (1995). Peroxi-some Proliferation and Its Role in Carcinogenesis: Views and Expert Opinions of an IARC Working Group, Lyon, 7-11 December, 1994. IARC Technical Rep. 24. IARC, Lyon.
    • (1995) IARC Technical Rep. 24
  • 24
    • 0037177413 scopus 로고    scopus 로고
    • Comparison of phthalate monoesters on gap junctional intercellular communication and peroxisome proliferation in rodent and human hepatocytes
    • Kamendulis, L., Isenberg, J., Smith, J., Pugh, G., Lington, A., and Klaunig, J. (2002). Comparison of phthalate monoesters on gap junctional intercellular communication and peroxisome proliferation in rodent and human hepatocytes. J. Toxicol. Environ. Health 65, 569-588.
    • (2002) J. Toxicol. Environ. Health , vol.65 , pp. 569-588
    • Kamendulis, L.1    Isenberg, J.2    Smith, J.3    Pugh, G.4    Lington, A.5    Klaunig, J.6
  • 25
    • 0020444298 scopus 로고
    • The carcinogenicity of dietary di(2-ethylhexyl)phthalate (DEHP) in Fischer 344 rats and B6C3F1 mice
    • Kluwe, W., Haseman, J., Douglas, J., and Huff, J. (1982). The carcinogenicity of dietary di(2-ethylhexyl)phthalate (DEHP) in Fischer 344 rats and B6C3F1 mice. J. Toxicol. Environ. Health 10, 797-815.
    • (1982) J. Toxicol. Environ. Health , vol.10 , pp. 797-815
    • Kluwe, W.1    Haseman, J.2    Douglas, J.3    Huff, J.4
  • 26
    • 0031943086 scopus 로고    scopus 로고
    • Subchronic toxicity of di(2-ethylhexyl) phthalate in common marmosets: Lack of peroxisomal proliferation, testicular atrophy or pancreatic acinar cell hyperplasia
    • Kurata, Y., Kidachi, F., Tokoyama, M., Toyota, N., Tsuchitani, M., and Katoh, M. (1998). Subchronic toxicity of di(2-ethylhexyl) phthalate in common marmosets: Lack of peroxisomal proliferation, testicular atrophy or pancreatic acinar cell hyperplasia. Toxicol. Sci. 42, 49-56.
    • (1998) Toxicol. Sci. , vol.42 , pp. 49-56
    • Kurata, Y.1    Kidachi, F.2    Tokoyama, M.3    Toyota, N.4    Tsuchitani, M.5    Katoh, M.6
  • 27
    • 0019742075 scopus 로고
    • Assay of peroxisomal β-oxidation of fatty acids
    • Lazarow, P. (1981). Assay of peroxisomal β-oxidation of fatty acids. Methods Enzymol. 72, 315-319.
    • (1981) Methods Enzymol. , vol.72 , pp. 315-319
    • Lazarow, P.1
  • 28
  • 29
    • 0034508456 scopus 로고    scopus 로고
    • Di-isononyl phthalate (DINP) and di-isodecyl phthalate (DIDP) are not mutagenic
    • McKee, R., Przygoda, R., Chirdon, M., Engelhardt, G., Stanley, M. (2000). Di-isononyl phthalate (DINP) and di-isodecyl phthalate (DIDP) are not mutagenic. J. Appl. Toxicol. 20, 491-497.
    • (2000) J. Appl. Toxicol. , vol.20 , pp. 491-497
    • McKee, R.1    Przygoda, R.2    Chirdon, M.3    Engelhardt, G.4    Stanley, M.5
  • 30
  • 31
    • 0031418657 scopus 로고    scopus 로고
    • Role of PPARα in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643
    • Peters, J., Cattley, R., and Gonzalez, F. (1997). Role of PPARα in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14,643. Carcinogenesis 18, 2029-2033.
    • (1997) Carcinogenesis , vol.18 , pp. 2029-2033
    • Peters, J.1    Cattley, R.2    Gonzalez, F.3
  • 33
    • 0001534583 scopus 로고
    • Acinar units and the pathophysiology of the liver
    • Ch. Rouiller, Ed. Academic Press, New York
    • Rappaport, A. (1963). Acinar units and the pathophysiology of the liver. In The Liver, (Ch. Rouiller, Ed.), Vol. 1, pp. 265-328. Academic Press, New York.
    • (1963) The Liver , vol.1 , pp. 265-328
    • Rappaport, A.1
  • 34
    • 0018858143 scopus 로고
    • Hepatic bloodflow: Morphologic aspects and physiologic regulation
    • (N. Javitt, Ed.), International Review of Physiology, Univ. Press, Baltimore, MD
    • Rappaport, A. (1980). Hepatic bloodflow: Morphologic aspects and physiologic regulation. In Liver and Biliary Tract Physiology (N. Javitt, Ed.), International Review of Physiology, Vol 21, Univ. Press, Baltimore, MD.
    • (1980) Liver and Biliary Tract Physiology , vol.21
    • Rappaport, A.1
  • 35
    • 0012985571 scopus 로고    scopus 로고
    • Species differences in response to the phthalate plasticizer monoisononyl phthalate (MINP) in vitro: A comparison of rat and human hepatocytes
    • Shaw, D., Lee, R., and Roberts, R. (2002). Species differences in response to the phthalate plasticizer monoisononyl phthalate (MINP) in vitro: A comparison of rat and human hepatocytes. Toxicologist 66 (1-S), 37.
    • (2002) Toxicologist , vol.66 , Issue.1 S , pp. 37
    • Shaw, D.1    Lee, R.2    Roberts, R.3
  • 37
    • 0034038221 scopus 로고    scopus 로고
    • Comparative in vivo hepatic effects of di-isononyl phthalate (DINP) and related C7-C11 dialkyl phthalates on gap junctional intercellular communication (GJIC), peroxisomal beta-oxidation (PBOX) and DNA synthesis in rat and mouse liver
    • Smith, J., Isenberg, J., Pugh, G., Kamendulis, L., Ackley, D., Lington, A., and Klaunig, J. (2000). Comparative in vivo hepatic effects of di-isononyl phthalate (DINP) and related C7-C11 dialkyl phthalates on gap junctional intercellular communication (GJIC), peroxisomal beta-oxidation (PBOX) and DNA synthesis in rat and mouse liver. Toxicol. Sci. 54, 312-321.
    • (2000) Toxicol. Sci. , vol.54 , pp. 312-321
    • Smith, J.1    Isenberg, J.2    Pugh, G.3    Kamendulis, L.4    Ackley, D.5    Lington, A.6    Klaunig, J.7
  • 38
    • 0000646057 scopus 로고    scopus 로고
    • Role of PPAR alpha in hepatic responses to diisononyl phthalate (DINP)
    • Valles, E., Laughter, A., Dunn, C., Cattley, R., and Corton, J. (2000). Role of PPAR alpha in hepatic responses to diisononyl phthalate (DINP). Toxicologist 54, 418.
    • (2000) Toxicologist , vol.54 , pp. 418
    • Valles, E.1    Laughter, A.2    Dunn, C.3    Cattley, R.4    Corton, J.5
  • 39
    • 0031969263 scopus 로고    scopus 로고
    • Receptor and nonreceptor-mediated, organ-specific toxicity of di(2-ethylhexyl) phthalate (DEHP) in peroxisome proliferator-activated alpha-null mice
    • Ward, J., Peters, J., Perella, C., and Gonzalez, F. (1998). Receptor and nonreceptor-mediated, organ-specific toxicity of di(2-ethylhexyl) phthalate (DEHP) in peroxisome proliferator-activated alpha-null mice. Toxicol. Pathol. 26, 240-246.
    • (1998) Toxicol. Pathol. , vol.26 , pp. 240-246
    • Ward, J.1    Peters, J.2    Perella, C.3    Gonzalez, F.4
  • 40
    • 70350129993 scopus 로고
    • An accurate and rapid method for the determination of proteins in small amounts of blood serum and plasma
    • Weichselbaum, T. (1946). An accurate and rapid method for the determination of proteins in small amounts of blood serum and plasma. Am. J. Clin. Pathol. 16, 40-49.
    • (1946) Am. J. Clin. Pathol. , vol.16 , pp. 40-49
    • Weichselbaum, T.1
  • 42
    • 0022390108 scopus 로고
    • Mutagenicity testing of di-2(ethylhexyl) phthalate and related chemicals in Salmonella
    • Zeiger, E., Haworth, S., Mortelmans, K., and Speck, W. (1985). Mutagenicity testing of di-2(ethylhexyl) phthalate and related chemicals in Salmonella. Environ. Mutagen. 7, 213-232.
    • (1985) Environ. Mutagen. , vol.7 , pp. 213-232
    • Zeiger, E.1    Haworth, S.2    Mortelmans, K.3    Speck, W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.