Localization and contents of paradisins, the most potent CYP3A4 inhibitors, in grapefruit Citrus paradisii and grapefruit juice

Natural Medicines

Volumn 56, Issue 6, 2002, Pages 264-267

  Ohta, Tomihisa ^a   Miyamoto, Yasuyo ^a   Maruyama, Takuro ^a   Kiuchi, Fumiyuki ^a   Tsukamoto, Sachiko ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

Citrus paradisii; CYP3A inhibition; Furanocoumarin dimers; Grapefruit; Grapefruit juice; Localization; Paradisin; Rutaceae

Indexed keywords

CITRUS PARADISII EXTRACT; CYTOCHROME P450 3A4; CYTOCHROME P450 INHIBITOR; PARADISIN A; PARADISIN B; PARADISIN C; PLANT EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CITRUS PARADISII; DRUG EFFECT; ENZYME INHIBITION; FOOD DRUG INTERACTION; GRAPEFRUIT; GRAPEFRUIT JUICE; IC 50; NONHUMAN; PLANT; STRUCTURE ANALYSIS;

EID: 0036964865     PISSN: 13403443     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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