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Volumn 51, Issue SUPPL. 2, 2002, Pages 26-32

Deregulation of SHP-2 tyrosine phosphatase by the Helicobacter pylori virulence factor CagA

Author keywords

CagA; Helicobacter pylori; Hummingbird phenotype; SHP 2; Tyrosine phosphorylation

Indexed keywords

CAGA PROTEIN; ONCOPROTEIN; PROTEIN TYROSINE PHOSPHATASE;

EID: 0036956442     PISSN: 00229717     EISSN: None     Source Type: Journal    
DOI: 10.2302/kjm.51.supplement2_26     Document Type: Conference Paper
Times cited : (8)

References (33)
  • 5
    • 0029043658 scopus 로고
    • Infection with Helicobacter Pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach
    • Blaser MJ, Perez-Perez GI, Kleanthous H, Cover TL, Peek RM, Chyou PH, Stemmermann GN, Nomura A, et al: Infection with Helicobacter Pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res 1995; 55: 2111-2115
    • (1995) Cancer Res , vol.55 , pp. 2111-2115
    • Blaser, M.J.1    Perez-Perez, G.I.2    Kleanthous, H.3    Cover, T.L.4    Peek, R.M.5    Chyou, P.H.6    Stemmermann, G.N.7    Nomura, A.8
  • 7
    • 0030975595 scopus 로고    scopus 로고
    • Risk for gastric cancer in people with CagA positive or CagA negative Helicobacter pylori infection
    • Personnet J, Friedman GD, Orentreich N, Vogelman H: Risk for gastric cancer in people with CagA positive or CagA negative Helicobacter pylori infection. Gut 1997; 40: 297-301
    • (1997) Gut , vol.40 , pp. 297-301
    • Personnet, J.1    Friedman, G.D.2    Orentreich, N.3    Vogelman, H.4
  • 8
    • 0033456273 scopus 로고    scopus 로고
    • Altered states: Involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori
    • Segal ED, Cha J, Lo J, Falkow S, Tompkins LS: Altered states: Involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori. Proc Natl Acad Sci USA 1999; 96: 14559-14564
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 14559-14564
    • Segal, E.D.1    Cha, J.2    Lo, J.3    Falkow, S.4    Tompkins, L.S.5
  • 10
    • 0033953359 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cag-driven host cell translocation
    • Stein M, Rappuoli R, Covacci A: Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cag-driven host cell translocation. Proc Natl Acad Sci USA 2000; 97: 1263-1268
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1263-1268
    • Stein, M.1    Rappuoli, R.2    Covacci, A.3
  • 11
    • 17344379177 scopus 로고    scopus 로고
    • Translocation of Helicobacter pylori CagA into gastric epithelial cells by type IV secretion
    • Odenbreit S, Puls J, Sedlmaier B, Gerland E, Fischer W, Haas R: Translocation of Helicobacter pylori CagA into gastric epithelial cells by type IV secretion. Science 2000; 287: 1497-1500
    • (2000) Science , vol.287 , pp. 1497-1500
    • Odenbreit, S.1    Puls, J.2    Sedlmaier, B.3    Gerland, E.4    Fischer, W.5    Haas, R.6
  • 13
    • 0036227053 scopus 로고    scopus 로고
    • c-Src/Lyn kinases activate Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs
    • Stein M, Bagnoli F, Halenbeck R, Rappuoli R, Fantl WJ, Covacci A: c-Src/Lyn kinases activate Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs. Mol Microbiol 2002; 43: 971-980
    • (2002) Mol Microbiol , vol.43 , pp. 971-980
    • Stein, M.1    Bagnoli, F.2    Halenbeck, R.3    Rappuoli, R.4    Fantl, W.J.5    Covacci, A.6
  • 14
    • 0036510363 scopus 로고    scopus 로고
    • Src is the kinase of the Helicobacter pylori cagA protein in vitro and in vivo
    • Selbach M, Moese S, Hauck CR, Meyer TF, Backert S: Src is the kinase of the Helicobacter pylori cagA protein in vitro and in vivo. J Biol Chem 2002; 277: 6775-6778
    • (2002) J Biol Chem , vol.277 , pp. 6775-6778
    • Selbach, M.1    Moese, S.2    Hauck, C.R.3    Meyer, T.F.4    Backert, S.5
  • 15
    • 0031878592 scopus 로고    scopus 로고
    • Variants of the 3′ region of the cagA gene in Helicobacter pylori isolates from patients with different H. pylori-associated diseases
    • Yamaoka Y, Kodama T, Kashima K, Graham DY, Sepulveda AR: Variants of the 3′ region of the cagA gene in Helicobacter pylori isolates from patients with different H. pylori-associated diseases. J Clin Micobiol 1998; 36: 2258-2263
    • (1998) J Clin Micobiol , vol.36 , pp. 2258-2263
    • Yamaoka, Y.1    Kodama, T.2    Kashima, K.3    Graham, D.Y.4    Sepulveda, A.R.5
  • 18
    • 0033845178 scopus 로고    scopus 로고
    • Involvement of an SHP-2-Rho small G protein pathway in hepatocyte growth factor/scatter factor-induced cell scattering
    • Kodama A, Matozaki T, Fukuhara A, Kikyo M, Ichihashi M, Takai Y: Involvement of an SHP-2-Rho small G protein pathway in hepatocyte growth factor/scatter factor-induced cell scattering. Mol Biol Cell 2000; 11: 2565-2575
    • (2000) Mol Biol Cell , vol.11 , pp. 2565-2575
    • Kodama, A.1    Matozaki, T.2    Fukuhara, A.3    Kikyo, M.4    Ichihashi, M.5    Takai, Y.6
  • 21
    • 0027432407 scopus 로고
    • Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine 1009, on the human platelet-derived growth factor receptor
    • Lechleider RJ, Sugimoto S, Bennett AM, Kashishian AS, Cooper JA, Shoelson SE, Walsh CT, Neel BG: Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine 1009, on the human platelet-derived growth factor receptor. J Biol Chem 1993; 268: 21478-21481
    • (1993) J Biol Chem , vol.268 , pp. 21478-21481
    • Lechleider, R.J.1    Sugimoto, S.2    Bennett, A.M.3    Kashishian, A.S.4    Cooper, J.A.5    Shoelson, S.E.6    Walsh, C.T.7    Neel, B.G.8
  • 22
    • 0028854920 scopus 로고
    • Potent stimulation of SH-PTP2 phosphatase activity by simultaneous occupancy of both SH2 domains
    • Pluskey S, Wandless TJ, Walsh CT, Shoelson SE: Potent stimulation of SH-PTP2 phosphatase activity by simultaneous occupancy of both SH2 domains. J Biol Chem 1995; 270: 2897-2900
    • (1995) J Biol Chem , vol.270 , pp. 2897-2900
    • Pluskey, S.1    Wandless, T.J.2    Walsh, C.T.3    Shoelson, S.E.4
  • 23
    • 0027531637 scopus 로고
    • SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases
    • Feng GS, Hui CC, Pawson T: SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases. Science 1993; 259: 1607-1611
    • (1993) Science , vol.259 , pp. 1607-1611
    • Feng, G.S.1    Hui, C.C.2    Pawson, T.3
  • 24
    • 0026471539 scopus 로고
    • Identification of a human src homology 2-containing protein-tyrosine-phosphatase: A putative homolog of Drosophila corkscrew
    • Freeman RM Jr, Plutzky J, Neel BG: Identification of a human src homology 2-containing protein-tyrosine-phosphatase: a putative homolog of Drosophila corkscrew. Proc Natl Acad Sci USA 1992; 89: 11239-11243
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 11239-11243
    • Freeman R.M., Jr.1    Plutzky, J.2    Neel, B.G.3
  • 25
    • 0027531954 scopus 로고
    • A widely expressed human protein-tyrosine phosphatase containing src homology 2 domains
    • Ahmad S, Banville D, Zhao Z, Fischer EH, Shen SH: A widely expressed human protein-tyrosine phosphatase containing src homology 2 domains. Proc Natl Acad Sci USA 1993; 90: 2197-2201
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 2197-2201
    • Ahmad, S.1    Banville, D.2    Zhao, Z.3    Fischer, E.H.4    Shen, S.H.5
  • 26
    • 0028322113 scopus 로고    scopus 로고
    • Purification and characterization of PTP2C, a widely distributed protein tyrosine phosphatase containing two SH2 domains
    • Zhao Z, Larocque R, Ho WT, Fischer EH, Shen SH: Purification and characterization of PTP2C, a widely distributed protein tyrosine phosphatase containing two SH2 domains. J Biol Chem 1997; 269: 8780-8785
    • (1997) J Biol Chem , vol.269 , pp. 8780-8785
    • Zhao, Z.1    Larocque, R.2    Ho, W.T.3    Fischer, E.H.4    Shen, S.H.5
  • 27
    • 0028021665 scopus 로고
    • Characterization of protein tyrosine phosphatase SH-PTP2. Study of phosphopeptide substrates and possible regulatory role of SH2 domains
    • Dechert U, Adam M, Harder KW, Clark-Lewis I, Jirik F: Characterization of protein tyrosine phosphatase SH-PTP2. Study of phosphopeptide substrates and possible regulatory role of SH2 domains. J Biol Chem 1994; 269: 5602-5611
    • (1994) J Biol Chem , vol.269 , pp. 5602-5611
    • Dechert, U.1    Adam, M.2    Harder, K.W.3    Clark-Lewis, I.4    Jirik, F.5
  • 28
    • 0033761488 scopus 로고    scopus 로고
    • The tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the met receptor tyrosine kinase
    • Maroun CR, Naujokas MA, Holgado-Madruga M, Wong AJ, Park M: The tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the met receptor tyrosine kinase. Mol Cell Biol 2000; 20: 8513-8525
    • (2000) Mol Cell Biol , vol.20 , pp. 8513-8525
    • Maroun, C.R.1    Naujokas, M.A.2    Holgado-Madruga, M.3    Wong, A.J.4    Park, M.5
  • 29
    • 3543036342 scopus 로고    scopus 로고
    • Protein-tyrosine phosphatase Shp-2 regulates cell spreading. Migration and Focal adhesion
    • Yu DH, Qu CK, Henegariu O, Lu X, Feng GS: Protein-tyrosine phosphatase Shp-2 regulates cell spreading. Migration and Focal adhesion. J Biol Chem 1998; 273: 21125-21131
    • (1998) J Biol Chem , vol.273 , pp. 21125-21131
    • Yu, D.H.1    Qu, C.K.2    Henegariu, O.3    Lu, X.4    Feng, G.S.5
  • 30
    • 0039441744 scopus 로고    scopus 로고
    • Concerted activity of tyrosine phosphatase SHP-2 and focal adhesion kinase in regulation of cell motility
    • Manes S, Mira E, Gomez-mouton C, Zhao ZJ, Lacalle RA, Martinez-A C: Concerted activity of tyrosine phosphatase SHP-2 and focal adhesion kinase in regulation of cell motility. Mol Cell Biol 1999; 19: 3125-3135
    • (1999) Mol Cell Biol , vol.19 , pp. 3125-3135
    • Manes, S.1    Mira, E.2    Gomez-mouton, C.3    Zhao, Z.J.4    Lacalle, R.A.5    Martinez-A, C.6
  • 33
    • 0030933277 scopus 로고    scopus 로고
    • Oncoprotein networks
    • Hunter T: Oncoprotein networks. Cell 1997; 88: 333-346
    • (1997) Cell , vol.88 , pp. 333-346
    • Hunter, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.