A major CYP2D6 autoepitope in autoimmune hepatitis type 2 and chronic hepatitis C is a three-dimensional structure homologous to other cytochrome P450 autoantigens

Autoimmunity

Volumn 35, Issue 8, 2002, Pages 501-513

  Sugimura, T ^a   Obermayer Straub, P ^a   Kayser, A ^a   Braun, S ^a   Loges, S ^a   Alex, B ^a   Luttig B ^a   Johnson, E F ^b   Manns, Michael P ^a   Strassburg, Christian P ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Autoimmune hepatitis type 2; Cytochromes P4502D6; Epitopes; Liver kidney microsomal antibodies

Indexed keywords

AMINO ACID; AUTOANTIGEN; CYTOCHROME P450; CYTOCHROME P450 2B1; CYTOCHROME P450 2D6; DIHYDROFOLATE REDUCTASE; EPITOPE; HYBRID PROTEIN; LIVER KIDNEY MICROSOME ANTIBODY TYPE 1; MICROSOME ANTIBODY; UNCLASSIFIED DRUG;

ADRENAL DISEASE; ANIMAL TISSUE; ANTIBODY TITER; ANTIGEN STRUCTURE; ARTICLE; ASSAY; AUTOIMMUNE HEPATITIS; AUTOIMMUNE HEPATITIS TYPE 2; AUTOIMMUNITY; BINDING SITE; BLOOD DONOR; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DISEASE CLASSIFICATION; DISEASE MARKER; DRUG INDUCED DISEASE; EPITOPE MAPPING; ESCHERICHIA COLI; GENETIC TRANSCRIPTION; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; IMMUNOFLUORESCENCE TEST; KIDNEY PARENCHYMA; LIVER PARENCHYMA; MAJOR CLINICAL STUDY; NONHUMAN; PROTEIN CONFORMATION; PROTEIN EXPRESSION; RAT; RHEUMATIC DISEASE; RNA TRANSLATION; SEROPREVALENCE; STRUCTURAL HOMOLOGY;

AMINO ACID SEQUENCE; AUTOANTIBODIES; CHRONIC DISEASE; CYTOCHROME P-450 CYP2D6; EPITOPE MAPPING; EPITOPES; HEPATITIS C; HEPATITIS, AUTOIMMUNE; HUMANS; MOLECULAR SEQUENCE DATA; PRECIPITIN TESTS;

EID: 0036940091     PISSN: 08916934     EISSN: None     Source Type: Journal    
DOI: 10.1080/0891693021000069556     Document Type: Article

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