Mixed multiple system atrophy and progressive supranuclear palsy: A clinical and pathological report of one case

Acta Neuropathologica

Volumn 103, Issue 1, 2002, Pages 82-87

  Takanashi, Masashi ^a   Ohta, Satoshi ^a   Matsuoka, Shuji ^a   Mori, Hideo ^a   Mizuno, Yoşhikuni ^a  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

synuclein; Multiple system atrophy; Progressive supranuclear palsy; Tau

Indexed keywords

ALPHA SYNUCLEIN; BENSERAZIDE; LEVODOPA; TAU PROTEIN;

AGED; AKINESIA; ARTICLE; ASTROCYTE; AUTONOMIC DYSFUNCTION; AUTOPSY; BASAL GANGLION; BRAIN STEM; CASE REPORT; CELL INCLUSION; CELL LOSS; CEREBELLAR ATAXIA; CLINICAL FEATURE; COMORBIDITY; DEATH; DISEASE SEVERITY; GLIA CELL; GLIOSIS; GLOBUS PALLIDUS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOREACTIVITY; INFERIOR OLIVE; MALE; MUSCLE RIGIDITY; NERVE CELL; NEUROFIBRILLARY TANGLE; NEUROLOGIC EXAMINATION; OBSERVATION; OLIGODENDROGLIA; PARKINSONISM; PONS ANGLE; PRIORITY JOURNAL; PROGRESSIVE SUPRANUCLEAR PALSY; PROTEIN DEFECT; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PUTAMEN; SHY DRAGER SYNDROME; SUBSTANTIA NIGRA; SUBTHALAMIC NUCLEUS;

AGED; ALPHA-SYNUCLEIN; BRAIN; BRAIN CHEMISTRY; FATAL OUTCOME; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MULTIPLE SYSTEM ATROPHY; NERVE TISSUE PROTEINS; SUPRANUCLEAR PALSY, PROGRESSIVE; SYNUCLEINS; TAU PROTEINS;

EID: 0036934180     PISSN: 00016322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004010100433     Document Type: Article

References (38)

1. Lantos PL (1998) The definition of multiple system atrophy: a review of recent developments. J Neuropthol Exp Neurol 57: 1099-1113
2. Cairns NJ, Atkinson PF, Hanger DP, Anderson BH, Daniel SE, Lantos PL (1997) Tau protein in the glial cytoplasmic inclusions of multiple system atrophy can be distinguished from abnormal tau in Alzheimer's disease. Neurosci Lett 230:49-52
3. Spilantini MG, Crowther RA, Jakes R, Cairns NJ, Lantos PL, Goedert M (1998) Filamentous α-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies. Neurosci Lett 251:205-208
4. Gai WP, Power JHT, Blumbergs PC, Blessing WW (1998) Multiple system atrophy: a new synuclein disease? Lancet 352: 547-548
5. Arima K, Ueda K, Sunohara N, Arakawa K, Hirai S, Nakamura M, Tonozuka-Uehara H, Kawai M (1998) NACP/α-synuclein immunoreactivity in fibrillary components of neuronal and oligodendroglial cytoplasmic inclusions in the pontine nuclei in multiple system atrophy. Acta Neuropathol 96:439-444
6. Tu P, Galvin JE, Baba M, Giasson B, Tomita T, Leight S, Nakajo S, Iwatsubo T, Trojanowski JQ, Lee VMY (1998) Glial cytoplasmic inclusions in white matter oligodendrocytes of, multiple system atrophy brains contain insoluble α-synuclein. Ann Neurol 44:415-422
7. Wakabayashi K, Hayashi S, Kakita A, Yamada M, Toyoshima Y, Yoshimoto M, Takahashi H (1998) Accumulation of α-synuclein/NACP is a cytopathological feature common to Lewy body disease and multiple system atrophy. Acta Neuropathol 96:445-452
8. Hardy J, Gwinn-Hardy K (1998) Genetic classification of primary neurodegenerative disease. Science 282:1075-1079
9. Dickson DW, Lin WL, Liu WK, Yen SH (1999) Multiple system atrophy: a sporadic synucleinopathy. Brain Pathol 9:721-732
10. Steven SMC, James EG (1996) Glial inclusions in CNS degenerative diseases. J Neuropathol Exp Neurol 55:499-508
11. Hauw JJ, Daniel SE, Dickson D, Horoupian DS, Jellinger K, Lantos PL, McKee A, Tabaton M, Litvan I (1994) Preliminary NINDS neuropathologic criteria for Steele-Richardson-Olszewski syndrome (progressive supranuclear palsy). Neurology 44:2015-2019
12. Dickson DW (1999) Neuropathologic differentiation of progressive supranuclear palsy and corticobasal degeneration. J Neurol 246 (Suppl 2):6-15
13. Colosimo C, Albanese A, Hughes AJ, Bruin VMS de, Lees AJ (1995) Some specific clinical features differentiate multiple system atrophy (striatonigral variety) from Parkinson's disease. Arch Neurol 52:294-298
14. Litvan I, Campbell G, Mangone CA, Verny M, McKee A, Chaudhuri KR, Jellinger K, Pearce RKB, D'Olhaberriague L (1997) Which clinical features differentiate progressive, supranuclear palsy (Steel-Richardson-Olszewski syndrome) from related disorders? A clinicopathological study. Brain 120:65-74
15. Gearing M, Olson DA, Watts RL, Mirra SS (1994) Progressive supranuclear palsy: neuropathologic and clinical heterogeneity. Neurology 44:1015-1024
16. Sasaki S, Maruyama S, Toyoda C (1991) A case of progressive supranuclear palsy with widespread senile plaques. J Neurol 238:345-348
17. Mori H, Yoshimura M, Tomonaga M, Yamanouchi H (1986) Progressive supranuclear palsy with Lewy bodies. Acta Neuropahol 71:344-346
18. D'Amato CJ, Sima AF, Foster NL, Dickson DW, Hicks SP (1991) Cerebral Lewy bodies with progressive supranuclear palsy. J Neuropathol Exp Neurol 50:308
19. Arima K, Murayama S, Oyanagi S, Akashi T, Inose T (1992) Presenile dementia with progressive supranuclear palsy tangles and Pick bodies: an unusual degenerative disorder involving the cerebral cortex, cerebral nuclei, and brain stem nuclei. Acta Neuropathol 84:128-134
20. Higuchi Y, Iwaki T, Tateishi J (1995) Neurodegeneration in the limbic and paralimbic system in progressive supranuclear palsy. Neuropathol Appl Neurobiol 21:246-254
21. Kobayashi K, Fukutani Y, Hayashi M, Miyazu K, Muramori F, Aoki T, Mukai M, Sasaki K, Isaki K, Koshino Y (1998) Nonfamilial olivopontocerebellar atrophy combined with late onset Alzheimer's disease: a clinico-pathological case report. J Neurol Sci 154:106-112
22. Martinez-Lage P, Munoz DG (1997) Prevalence and disease associations of argyrophilic grains of Braak. J Neuropathol Exp Neurol 56:157-164
23. Wakabayashi K, Kawachi I, Toyoshima Y, Takahashi H (1999) Occurrence of argyrophilic grains in multiple system atrophy: histopathological examination of 26 autopsy cases. No To Shinkei 51:433-437
24. Horoupian DS, Dickson DW (1991) Striatonigral degeneration, olivopontocerebellar atrophy and "atypical" Pick disease. Acta Neuropathol 81:287-295
25. Morioka E, Kuroda S, Kuyama K, Otsuki S, Hosokawa K, Namba R (1987) An autopsy case of multiple system atrophy with many Lewy bodies - Striatonigral degeneration, olivopontocerebellar atrophy and autonomic nerve nuclei involvement in the spinal cord. No To Shinkei 39:361-366
26. Renkawek K, Horstink MWIM (1993) Striatonigral degeneration with neurofibrillary tangles. Acta Neuropthol 86:405-410
27. Schrag A, Ben-Shlomo Y, Quinn NP (1999) Prevalence of progressive supranuclear palsy and multiple system atrophy: a cross-sectional study. Lancet 354:1771-1775
28. Bower JH, Maraganore DM, McDonnell SK, Rocca WA (1997) Incidence of progressive supranuclear palsy and multiple system atrophy in Olmsted Country, Minnesota, 1976 to 1990. Neurology 49:1284-1288
29. Kosaka K (1990) Diffuse Lewy body disease in Japan. J Neurol 237:197-204
30. Hansen L, Salmon D, Galasko D, Masliah E, Katzman R, DeTeresa R, Thal L, Pay MM, Hofstetter R, Klauber M, Rice V, Butters N, Alford M (1990) The Lewy variant of Alzheimer's disease. Neurology 40:1-8
31. Perry RH, Irving D, Blessed G, Fairbairn A, Perry EK (1990) Senile dementia of Lewy body type. A clinically and neuropathologically distinct form of Lewy body dementia in the elderly. J Neurol Sci 95:119-139
32. Lippa CF, Fujiwara H, Mann DMA, Giasson B, Baba M, Schmidt ML, Nee LE, O'Connell Brendan, Pollen DA, George- Hyslop PS, Ghetti B, Nochlin D, Bird TD, Cairns NJ, Lee VM Y, Iwatsubo T, Trojanowski JQ (1998) Lewy bodies contain altered α-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes. Am J Pathol 153:1365-1370
33. Lippa CF, Luise M, Lee VMY, Trojanowski JQ (1999) Antibodies to α-synuclein detect Lewy bodies in many Down's syndrome brains with Alzheimer's disease. Ann Neurol 45: 353-357
34. Schmidt ML, Martin JA, Lee VMY, Trojanowski JQ (1996) Convergence of Lewy bodies and neurofibrillary tangles in amygdala neurons of Alzheimer's disease and Lewy body disorders. Acta Neuropathol 91:475-481
35. Iseki E, Marui W, Kosaka K, Ueda K (1999) Frequent coexistence of Lewy bodies and neurofibrillary tangles in the same neurons of patients with diffuse Lewy body disease. Neurosci Lett 265:9-12
36. Galloway PG, Bergeron C, Perry G (1989) The presence of tau distinguishes Lewy bodies of diffuse Lewy body disease from those of idiopathic Parkinson's disease. Neurosci Lett 100: 6-10
37. Marui W, Iseki E, Ueda K, Kosaka K (2000) Occurrence of human α-synuclein immunoreactive neurons with neurofibrillary tangles formation in the limbic areas of patients with Alzheimer's disease. J Neurol Sci 174:81-84
38. Arima K, Hirai S, Sunohara N, Aoto K, Izumiyama Y, Ueda K, Ikeda K, Kawai M (1999) Cellular co-localization of phosphorylated tau- and NACP/α-synuclein-epitopes in Lewy bodies in sporadic Parkinson's disease and in dementia with Lewy bodies. Brain Res 843:53-61