The multiple endocrine neoplasia type 1 gene product, menin, inhibits the human prolactin promoter activity

Journal of Molecular Endocrinology

Volumn 29, Issue 3, 2002, Pages 297-304

  Namihira, H ^a   Sato, M ^a   Murao, K ^a   Cao, W M ^a   Matsubara, S ^a   Imachi, H ^a   Niimi, M ^a   Dobashi, H ^a   Wong, N C W ^b   Ishida, T ^a  

^a KAGAWA UNIVERSITY   (Japan)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GENE PRODUCT; METHIONINE; PROLACTIN; THYMIDINE;

ADENOHYPOPHYSIS DISEASE; ANIMAL CELL; CARCINOGENESIS; CELL PROLIFERATION; CELL STRAIN GH3; CONTROLLED STUDY; DNA SYNTHESIS; ENDOCRINE TUMOR; EXPRESSION VECTOR; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GENETIC CODE; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HORMONE INHIBITION; HYPOPHYSIS CELL; HYPOPHYSIS TUMOR; JAPAN; MULTIGENE FAMILY; MULTIPLE ENDOCRINE NEOPLASIA; NONHUMAN; PANCREAS ISLET CELL TUMOR; PARATHYROID TUMOR; PRIORITY JOURNAL; PROLACTINOMA; PROTEIN EXPRESSION; RAT; REVIEW;

ANIMALS; BLOTTING, WESTERN; CELL DIVISION; CELL LINE; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; NEOPLASM PROTEINS; PROLACTIN; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS; RATS; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0036910113     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/jme.0.0290297     Document Type: Review

References (32)

1. Agarwal SK, Kester MB, Debelenko LV, Heppner C, Emmert-Buck MR, Skarulis MC, Doppman JL, Kim YS, Lubensky IA, Zhuang Z et al. 1997 Germline mutations of the MEN1 gene, in familial multiple endocrine neoplasia type 1 and related states. Human Molecular Genetics 6 1169-1175.
2. Agarwal SK, Guru SC, Heppner C, Erdos MR, Collins RM, Park SY, Saggar S, Chandrasekharappa SC, Collins F, Spiegel AM et al. 1999 Menin interacts with the API transcription factor Jun D and represses Jun D-activated transcription. Cell 96 143-152.
3. Asa SL, Somers K & Ezzat S 1998 The MEN-1 gene is rarely down-regulated in pituitary adenomas. Journal of Clinical Endocrinology and Metabolism 83 3210-3212.
4. Bassett JH, Forbes SA, Pannett AA, Lloyd SL, Christie PT, Wooding C, Harding B, Besser GM, Edwards CR, Monson JP et al. 1998 Characterization of mutations in patients with multiple endocrine neoplasia type 1. American Journal of Human Genetics 62 232-244.
5. Berwaer M, Monget P, Peers B, Mathy-Hartert M, Bellefroid E, Davis JR, Belayew A & Martial JA 1991 Multihormonal regulation of the human prolactin gene expression from 5000 bp of its upstream sequence. Molecular and Cellular Endocrinolgy 80 53-64.
6. Berwaer M, Peers B, Nalda AM, Monget P, Davis JR, Belayew A & Martial JA 1993 TRH and EGF induce human prolactin expression via identical multiple cis-elements. Molecular and Cellular Endocrinolagy 92 1-7.
7. Bhuiyan MM, Sato M, Murao K, Imachi H, Namihira H & Takahara J 2000 Expression of menin in parathyroid tumors. Journal of Clinical Endocrinology and Metabolism 85 2615-2619.
8. Caccavelli L, Manfroid I, Martial JA & Muller M 1998 Transcription factor AP1 is involved in basal and okadaic acid-stimulated activity of the human PRL promoter. Molecular Endocrinology 12 1215-1227.
9. Chandrasekharappa SC, Guru SC, Manickam P, Olufemi SE, Collins FS, Emmert-Buck MR, Debelenko LV, Zhuang Z, Lubensky IA, Liotta LA et al. 1997 Positional cloning of the gene for multiple endocrine neoplasia-type 1. Sciencc 276 404-407.
10. Farid NR, Buehler S, Russell NA, Maroun FB & Allerdice P 1980 Prolactinomas in familial multiple endocrine neoplasia syndrome type 1. American Journal of Medicine 69 874-880.
11. Farrell WE, Simpson DJ, Bicknell J, Magnay JL, Kyrodimou E, Thakker RV & Clayton RN 1999 Sequence analysis and transcript expression of the MEN1 gene in sporadic pituitary tumours. British Journal of Cancer 80 44-50.
12. Fujita T, Yamaji Y, Sato M, Murao K & Takahara J 1994 Gene expression of somatostatin receptor subtypes, SSTR I and SSTR II, in human lung cancer cell lines. Life Sciences 55 1797-1806.
13. Guru SC, Goldsmith PK, Burns AL, Marx SJ, Spiegel AM, Collins FS & Chandrasekharappa SC 1998 Menin, the products of the MEN1 gene, is a nuclear protein. PNAS 95 1630-1634.
14. Heppner C, Kester MB, Agarwal SK, Debelenko LV, Emmert-Buck MR, Guru SC, Manickam P, Olufemi SE, Skarulis MC, Doppman JL et al. 1997 Somatic mutation of the MEN1 gene in parathyroid tumours. Nature Genetics 16 375-378.
15. Heppner C, Bilimoria KY, Agarwal SK, Kester M, Whitty LJ, Guru SC, Chandrasekharappa SC, Collins FS, Spiegel AM, Marx SJ et al. 2001 The tumor suppressor protein menin interacts with NF-kappa B proteins and inhibits NF-kappa B-mediated transactivation. Oncogene 20 4917-4925.
16. Kaji H, Canaff L, Goltzman D & Hendy GN 1999 Cell cycle regulation of menin expression. Cancer Research 59 5097-5101.
17. Krown KA, Wang Y-F, Ho TWC, Kelly P & Walker AM 1992 Prolactin isoform 2 as an autocrine growth factor for GH3 cells. Endocrinology 131 595-602.
18. Lemmens I, Van de Ven WJ, Kas K, Zhang CX, Giraud S, Wautot V, Buisson N, De Witte K, Salandre J, Lenoir G et al. 1997 Identification of the multiple endocrine neoplasia type 1 (MEN1) gene. Human Molecular Genetics 6 1177-1183.
19. Namihira H, Sato M, Miyauchi A, Ohye H, Matsubara S, Bhuiyan MM, Murao K, Ameno S, Ameno K, Ijiri I et al. 2000 Different phenotypes of multiple endocrine neoplasia type 1 (MEN1) in monozygotic twins found in a Japanese MEN1 family with MEN1 gene mutation. Endocrine Journal 47 37-43.
20. Niimi M, Sato M, Murao K, Takahara J & Kawanishi K 1994 Effect of excitatory amino acid receptor agonists on secretion of growth hormone as assessed by the reverse hemolytic plaque assay. Neuroendocrinology 60 173-178.
21. Olufemi SE, Green JS, Manickam P, Guru SC, Agarwal SK, Kester MB, Dong Q, Burns AL, Spiegel AM, Marx SJ et al. 1998 Common ancestral mutation in the MEN1 gene is likely responsible for the prolactinoma variant of MEN1 (MEN1 Burin) in four kindreds from Newfoundland. Human Mutation 11 264-269.
22. Prezant TR, Levine J & Melmed S 1998 Molecular characterization of the MEN1 tumor suppressor gene in sporadic pituitary tumors. Journal of Clinical Endocrinology and Metabolism 83 1388-1391.
23. Saiardi A, Bozzi Y, Baik J-H & Borrelli E 1997 Antiproliferative role of dopamine: loss of D2 receptors causes hormonal dysfunction and pituitary hyperplasia. Neuron 19 115-126.
24. Sato M, Matsubara S, Miyauchi A, Ohye H, Imachi H, Murao K & Takahara J 1998 Identification of five novel germline mutations of the MEN1 gene in Japanese multiple endocrine neoplasia type 1 (MEN1) families. Journal of Medical Genetics 35 915-919.
25. Schmidt MC, Henke RT, Stangl AP, Meyer-Puttlitz B, Stoffel-Wagner B, Schramm J & von Deimling A 1999 Analysis of the MEN1 gene in sporadic pituitary adenomas. Journal of Pathology 188 168-173.
26. Sheppherd JJ 1991 The natural history of MEN1 which may be highly unrecognized rather than highly uncommon. Archives of Surgery 126 935-952.
27. Tamaki M, Sato M, Matsubara S, Wada Y & Takahara J 1996 Dexamethasone increases growth hormone (GH)-releasing hormone (GRH) receptor mRNA levels in cultured rat anterior pituitary cells. Journal of Neuroendocrinology 8 475-480.
28. Tanaka C, Kimura T, Yang P, Moritani M, Yamaoka T, Yamada S, Sano T, Yoshimoto K & Itakura M 1998 Analysis of loss of heterozygosity on chromosome 11 and infrequent inactivation of the MEN1 gene in sporadic pituitary adenomas. Journal of Clinical Endocrinology and Metabolism 83 2631-2634.
29. Trump D, Farren B, Wooding C, Pang JT, Besser GM, Buchanan KD, Edwards CR, Heath DA, Jackson CE, Jansen S et al. 1996 Clinical studies of multiple endocrine neoplasia type 1 (MEN1). Quarterly Journal of Medicine 89 653-659.
30. Truong AT, Duez C, Belayew A, Renard A, Pictet R, Bell GI & Martial JA 1984 Isolation and characterization of the human prolactin gene. EMBO Journal 3 429-437.
31. Yokote R, Sato M, Matsubara S, Ohye H, Niimi M, Murao K & Takahara J 1998 Molecular cloning and gene expression of growth hormone-releasing pepticle receptor in rat tissues. Peptides 19 15-20.
32. Zhuang Z, Ezzat SZ, Vortmeyer AO, Weil R, Oldfield EH, Park WS, Pack S, Huang S, Agarwal SK, Guru SC et al. 1997 Mutations of the MEN1 tumor suppressor gene in pituitary tumors. Cancer Research 57 5446-5451.