Common ancestral mutation in the MEN1 gene is likely responsible for the prolactinoma variant of MEN1 (MEN1(Burin)) in four kindreds from Newfoundland

Human Mutation

Volumn 11, Issue 4, 1998, Pages 264-269

  Olufemi, Shodimu Emmanuel ^a   Green, Jane S ^b   Manickam, Pachiappan ^a   Guru, Siradanahalli C ^a   Agarwal, Sunita K ^c   Kester, Mary Beth ^c   Dong, Qihan ^c,e   Burns, A Lee ^c   Spiegel, Allen M ^c   Marx, Stephen J ^c   Collins, Francis S ^a   Chandrasekharappa, Settara C ^a,d  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^b MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

^e UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Founder effect; MEN1 gene; MEN1(Burin); Menin; Newfoundland; Prolactinoma

Indexed keywords

ARTICLE; AUTOSOMAL DOMINANT DISORDER; CANADA; GENE LOCUS; GENE MUTATION; HAPLOTYPE; HUMAN; MULTIPLE ENDOCRINE NEOPLASIA; NONSENSE MUTATION; NUCLEOTIDE SEQUENCE; PARATHYROID TUMOR; PRIORITY JOURNAL; PROLACTINOMA;

ALLELES; AMINO ACID SEQUENCE; BASE SEQUENCE; CHROMOSOMES, HUMAN, PAIR 11; DNA; FEMALE; FOUNDER EFFECT; GENETIC MARKERS; HAPLOTYPES; HUMANS; LINKAGE (GENETICS); MALE; MOLECULAR SEQUENCE DATA; MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; NEWFOUNDLAND; PEDIGREE; PITUITARY NEOPLASMS; POINT MUTATION; POLYMERASE CHAIN REACTION; PROLACTINOMA;

EID: 7144229389     PISSN: 10597794     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-1004(1998)11:4<264::AID-HUMU2>3.0.CO;2-V     Document Type: Article

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