-
1
-
-
0032054839
-
Consensus for the use of fibrates in the treatment of dyslipoproteinemia and coronary heart disease
-
Fruchart JC, Brewer HB, Leitersdorf E. Consensus for the use of fibrates in the treatment of dyslipoproteinemia and coronary heart disease. Am J Cardiol 1998;81:912-7.
-
(1998)
Am J Cardiol
, vol.81
, pp. 912-917
-
-
Fruchart, J.C.1
Brewer, H.B.2
Leitersdorf, E.3
-
2
-
-
8944252340
-
Opposite regulation of human versus mouse apolipoprotein A-I by fibrate in human apolipoprotein A-I transgenic mice
-
Berthou L, Duverger N, Emmanuel F, Langouet S, Auwerx J, Guillouzo A, et al. Opposite regulation of human versus mouse apolipoprotein A-I by fibrate in human apolipoprotein A-I transgenic mice. J Clin Invest 1996;97:2408-16.
-
(1996)
J Clin Invest
, vol.97
, pp. 2408-2416
-
-
Berthou, L.1
Duverger, N.2
Emmanuel, F.3
Langouet, S.4
Auwerx, J.5
Guillouzo, A.6
-
3
-
-
0029791412
-
PPARα and PPARγ activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene
-
Schoonjans K, Peinado-Onsurbe J, Lefebvre AM, Heyman RA, Briggs M, Deeb S, et al. PPARα and PPARγ activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene. EMBO J 1996;15:5336-48.
-
(1996)
EMBO J
, vol.15
, pp. 5336-5348
-
-
Schoonjans, K.1
Peinado-Onsurbe, J.2
Lefebvre, A.M.3
Heyman, R.A.4
Briggs, M.5
Deeb, S.6
-
4
-
-
0028817459
-
Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. A potential mechanism for the hypolipidemic action of fibrates
-
Staels B, Vu-Dac N, Kosykh VA, Saladin R, Fruchart JC, Dallongeville J et al. Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. A potential mechanism for the hypolipidemic action of fibrates. J Clin Invest 1995;95:705-12.
-
(1995)
J Clin Invest
, vol.95
, pp. 705-712
-
-
Staels, B.1
Vu-Dac, N.2
Kosykh, V.A.3
Saladin, R.4
Fruchart, J.C.5
Dallongeville, J.6
-
5
-
-
2842575955
-
Peroxisomal proliferator activated receptors (PPARs): Molecular targets for hypolipidaemic agents and insulin sensitisers
-
Smith SA. Peroxisomal proliferator activated receptors (PPARs): Molecular targets for hypolipidaemic agents and insulin sensitisers. Pharmacol Rev Commun 1996;8:57-64.
-
(1996)
Pharmacol Rev Commun
, vol.8
, pp. 57-64
-
-
Smith, S.A.1
-
6
-
-
0033305213
-
Peroxisomal proliferator-activated receptors: Nuclear control of metabolism
-
Desverge B, Wahli W. Peroxisomal proliferator-activated receptors: Nuclear control of metabolism. Endocr Rev 1999;20:649-88.
-
(1999)
Endocr Rev
, vol.20
, pp. 649-688
-
-
Desverge, B.1
Wahli, W.2
-
7
-
-
0030766476
-
Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor α-deficient mice
-
Peters JM, Hennuyer N, Staels B, Fruchart JC, Fievet C, Gonzalez FJ, et al. Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor α-deficient mice. J Biol Chem 1997;272:27307-12.
-
(1997)
J Biol Chem
, vol.272
, pp. 27307-27312
-
-
Peters, J.M.1
Hennuyer, N.2
Staels, B.3
Fruchart, J.C.4
Fievet, C.5
Gonzalez, F.J.6
-
8
-
-
0024509605
-
Biochemical mechanisms of induction of hepatic peroxisome proliferation
-
Lock EA, Mitchell AM, Elcombe CR. Biochemical mechanisms of induction of hepatic peroxisome proliferation. Annu Rev Pharmacol Toxicol 1980;29:145-63.
-
(1980)
Annu Rev Pharmacol Toxicol
, vol.29
, pp. 145-163
-
-
Lock, E.A.1
Mitchell, A.M.2
Elcombe, C.R.3
-
9
-
-
0026517010
-
Control of the peroxisomal beta-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPARs)
-
Dreyer C, Krey G, Keller H, Givel F, Helftenbein G, Wahli W. Control of the peroxisomal beta-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPARs). Cell 1992;68:879-87.
-
(1992)
Cell
, vol.68
, pp. 879-887
-
-
Dreyer, C.1
Krey, G.2
Keller, H.3
Givel, F.4
Helftenbein, G.5
Wahli, W.6
-
10
-
-
0031418657
-
Role of PPARα in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14, 643
-
Peters JM, Cattley RC, González FJ. Role of PPARα in the mechanism of action of the nongenotoxic carcinogen and peroxisome proliferator Wy-14, 643. Carcinogenesis 1997;18:2029-33.
-
(1997)
Carcinogenesis
, vol.18
, pp. 2029-2033
-
-
Peters, J.M.1
Cattley, R.C.2
González, F.J.3
-
11
-
-
0031838516
-
Do peroxisome proliferating compounds pose a hepatocarcinogenic hazard to humans?
-
Cattley RC, DeLuca J, Elcombe C, Fenner-Crisp P, Lake BG, Marsman DS, et al. Do peroxisome proliferating compounds pose a hepatocarcinogenic hazard to humans? Reg Toxicol Pharmacol 1998;27:47-60.
-
(1998)
Reg Toxicol Pharmacol
, vol.27
, pp. 47-60
-
-
Cattley, R.C.1
DeLuca, J.2
Elcombe, C.3
Fenner-Crisp, P.4
Lake, B.G.5
Marsman, D.S.6
-
12
-
-
0030024585
-
Carcinogenicity of lipid-lowering drugs
-
Newman TB, Hulley SB. Carcinogenicity of lipid-lowering drugs. JAMA 1996;275:55-60.
-
(1996)
JAMA
, vol.275
, pp. 55-60
-
-
Newman, T.B.1
Hulley, S.B.2
-
13
-
-
0027959552
-
Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators
-
Mukherjee R, Jow L, Noonan D, McDonnell DP. Human and rat peroxisome proliferator activated receptors (PPARs) demonstrate similar tissue distribution but different responsiveness to PPAR activators. J Steroid Biochem Mol Biol 1994;3-4:157-66.
-
(1994)
J Steroid Biochem Mol Biol
, vol.3-4
, pp. 157-166
-
-
Mukherjee, R.1
Jow, L.2
Noonan, D.3
McDonnell, D.P.4
-
14
-
-
0030047184
-
Identification of a peroxisome proliferator responsive element upstream of the human peroxisomal fatty acyl-coenzyme A oxidase gene
-
Varanasi U, Chu R, Huang Q, Castellon R, Yeldandi AV, Reddy JK. Identification of a peroxisome proliferator responsive element upstream of the human peroxisomal fatty acyl-coenzyme A oxidase gene. J Biol Chem 1996;271:2147-55.
-
(1996)
J Biol Chem
, vol.271
, pp. 2147-2155
-
-
Varanasi, U.1
Chu, R.2
Huang, Q.3
Castellon, R.4
Yeldandi, A.V.5
Reddy, J.K.6
-
15
-
-
0031952238
-
Peroxisome proliferator activated receptor-α in human liver
-
Palmer CNA, Hsu M-H, Griffin KJ, Raucy JL, Johson EF. Peroxisome proliferator activated receptor-α in human liver. Mol Pharmacol 1998;53:14-22.
-
(1998)
Mol Pharmacol
, vol.53
, pp. 14-22
-
-
Palmer, C.N.A.1
Hsu, M.-H.2
Griffin, K.J.3
Raucy, J.L.4
Johson, E.F.5
-
16
-
-
0033304779
-
A truncated human peroxisome proliferator-activated receptor α splice variant with dominant negative activity
-
Gervois P, Pineda I, Chinetti G, Grötzinger T, Dubois G, Fruchart JC, et al. A truncated human peroxisome proliferator-activated receptor α splice variant with dominant negative activity. Mol Endocrinol 1999;13:1535-49.
-
(1999)
Mol Endocrinol
, vol.13
, pp. 1535-1549
-
-
Gervois, P.1
Pineda, I.2
Chinetti, G.3
Grötzinger, T.4
Dubois, G.5
Fruchart, J.C.6
-
17
-
-
0014876627
-
Rapid method for the isolation of lipoproteins from human serum by precipitation with polyanions
-
Burstein M, Scholnick HR, Morfin R. Rapid method for the isolation of lipoproteins from human serum by precipitation with polyanions. J Lipid Res 1970;11:583-91.
-
(1970)
J Lipid Res
, vol.11
, pp. 583-591
-
-
Burstein, M.1
Scholnick, H.R.2
Morfin, R.3
-
18
-
-
0015348189
-
Estimation of the concentration of low density lipoprotein cholesterol without use of the preparative ultracentrifuge
-
Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low density lipoprotein cholesterol without use of the preparative ultracentrifuge. Clin Chem 1972;18:499-506.
-
(1972)
Clin Chem
, vol.18
, pp. 499-506
-
-
Friedewald, W.T.1
Levy, R.I.2
Fredrickson, D.S.3
-
19
-
-
0020696964
-
Immunonephelometric determination of apolipoprotein A-I in hyperlipoproteinemic serum
-
Heuck CC, Erbe I, Flint-Hansen P. Immunonephelometric determination of apolipoprotein A-I in hyperlipoproteinemic serum. Clin Chem 1983;29:120-5.
-
(1983)
Clin Chem
, vol.29
, pp. 120-125
-
-
Heuck, C.C.1
Erbe, I.2
Flint-Hansen, P.3
-
20
-
-
0021021710
-
Examination of a competitive enzyme-linked immunoassay (CELIA) technique and laser nephelometric immunoassay technique for measurement of apolipoprotein B
-
Vander Heiden GL, Sasse EA, Yorde DE, Madiedo G, Barboriak JJ. Examination of a competitive enzyme-linked immunoassay (CELIA) technique and laser nephelometric immunoassay technique for measurement of apolipoprotein B. Clin Chim Acta 1983;135:209-18.
-
(1983)
Clin Chim Acta
, vol.135
, pp. 209-218
-
-
Vander Heiden, G.L.1
Sasse, E.A.2
Yorde, D.E.3
Madiedo, G.4
Barboriak, J.J.5
-
21
-
-
0033623803
-
Differences in the formation of PPARα-RXR/acoPPRE complexes between responsive and nonresponsive species upon fibrate administration
-
Rodríguez C, Noé V, Cabrero A, Ciudad CJ, Laguna JC. Differences in the formation of PPARα-RXR/acoPPRE complexes between responsive and nonresponsive species upon fibrate administration. Mol Pharmacol 2000;58:185-93.
-
(2000)
Mol Pharmacol
, vol.58
, pp. 185-193
-
-
Rodríguez, C.1
Noé, V.2
Cabrero, A.3
Ciudad, C.J.4
Laguna, J.C.5
-
22
-
-
0034175995
-
Is there an association between lipid-lowering drugs and cholecystectomy?
-
Mamdani MM, van Walraven C, Bica A, Williams JI, Naylor CD. Is there an association between lipid-lowering drugs and cholecystectomy? Am J Med 2000;108:418-21.
-
(2000)
Am J Med
, vol.108
, pp. 418-421
-
-
Mamdani, M.M.1
Van Walraven, C.2
Bica, A.3
Williams, J.I.4
Naylor, C.D.5
-
23
-
-
0002450306
-
Hyperlipoproteinemia, hypolipidemic treatment, and gallstone disease
-
Einarsson K, Angelin B. Hyperlipoproteinemia, hypolipidemic treatment, and gallstone disease. Atheroscler Rev 1986;15:67-97.
-
(1986)
Atheroscler Rev
, vol.15
, pp. 67-97
-
-
Einarsson, K.1
Angelin, B.2
-
24
-
-
0029143455
-
Effects of different phenotypes of hypercholesterolemia and of treatment with fibric acid derivatives on the rates of cholesterol 7α-hydroxylation in humans
-
Bertolotti M, Concari M, Loria P, Abate N, Pinetti A, Guicciardi ME, et al. Effects of different phenotypes of hypercholesterolemia and of treatment with fibric acid derivatives on the rates of cholesterol 7α-hydroxylation in humans. Arterioscler Thromb Vasc Biol 1995;15:1064-9.
-
(1995)
Arterioscler Thromb Vasc Biol
, vol.15
, pp. 1064-1069
-
-
Bertolotti, M.1
Concari, M.2
Loria, P.3
Abate, N.4
Pinetti, A.5
Guicciardi, M.E.6
-
25
-
-
0032562494
-
Effect of hypolipidemic drugs on key enzyme activities related to lipid metabolism in normolipidemic rabbits
-
Alegret M, Verd JC, Díaz C, Hernández G, Adzet T, Sánchez RM, et al. Effect of hypolipidemic drugs on key enzyme activities related to lipid metabolism in normolipidemic rabbits. Eur J Pharmacol 1998;347:283-91.
-
(1998)
Eur J Pharmacol
, vol.347
, pp. 283-291
-
-
Alegret, M.1
Verd, J.C.2
Díaz, C.3
Hernández, G.4
Adzet, T.5
Sánchez, R.M.6
-
26
-
-
0033999108
-
Peroxisome proliferator-activated receptor α(PPARα) and agonist inhibit cholesterol 7α-hydroxylase gene (CYP7A1) transcription
-
Marrapodi M, Chiang JYL. Peroxisome proliferator-activated receptor α(PPARα) and agonist inhibit cholesterol 7α-hydroxylase gene (CYP7A1) transcription. J Lipid Res 2000;41:514-20.
-
(2000)
J Lipid Res
, vol.41
, pp. 514-520
-
-
Marrapodi, M.1
Chiang, J.Y.L.2
-
27
-
-
0033545824
-
Beneficial effects of fibrates on apolipoprotein A-I metabolism occur independently of any peroxisome proliferative response
-
Hennuyer N, Poulain P, Madsen L, Berge RK, Houdebine LM, Branellec D, et al. Beneficial effects of fibrates on apolipoprotein A-I metabolism occur independently of any peroxisome proliferative response. Circulation 1999;99:2445-51.
-
(1999)
Circulation
, vol.99
, pp. 2445-2451
-
-
Hennuyer, N.1
Poulain, P.2
Madsen, L.3
Berge, R.K.4
Houdebine, L.M.5
Branellec, D.6
-
28
-
-
0034957825
-
Regulation of liver carnitine palmitoyltransferase I gene expression by hormones and fatty acids
-
Louet JF, Le May C, Pégorier JP, Decaux JF, Girard J. Regulation of liver carnitine palmitoyltransferase I gene expression by hormones and fatty acids. Biochem Soc Trans 2001;29:310-6.
-
(2001)
Biochem Soc Trans
, vol.29
, pp. 310-316
-
-
Louet, J.F.1
Le May, C.2
Pégorier, J.P.3
Decaux, J.F.4
Girard, J.5
-
29
-
-
0029090991
-
Differential effects of fibrates on the acyl composition of microsomal phospholipids in rats
-
Vázquez M, Muñoz S, Alegret M, Adzet T, Merlos M, Laguna JC. Differential effects of fibrates on the acyl composition of microsomal phospholipids in rats. Br J Pharmacol 1995;116:2067-75.
-
(1995)
Br J Pharmacol
, vol.116
, pp. 2067-2075
-
-
Vázquez, M.1
Muñoz, S.2
Alegret, M.3
Adzet, T.4
Merlos, M.5
Laguna, J.C.6
-
30
-
-
0025333458
-
Interruption of long-term lipid-lowering treatment with bezafibrate in hypertriglyceridaemic patients. Effects on lipoprotein composition, lipase activities and the plasma lipid fatty acid spectrum
-
Vessby B, Lithell H. Interruption of long-term lipid-lowering treatment with bezafibrate in hypertriglyceridaemic patients. Effects on lipoprotein composition, lipase activities and the plasma lipid fatty acid spectrum. Atherosclerosis 1990;82:137-43.
-
(1990)
Atherosclerosis
, vol.82
, pp. 137-143
-
-
Vessby, B.1
Lithell, H.2
-
31
-
-
0028969079
-
Selective modification of rat hepatic microsomal fatty acid chain elongation and desaturation by fibrates. Relationship with their activity as peroxisome proliferators
-
Alegret M, Cerqueda E, Ferrando R, Vázquez M, Sánchez RM, Adzet T, et al. Selective modification of rat hepatic microsomal fatty acid chain elongation and desaturation by fibrates. Relationship with their activity as peroxisome proliferators. Br J Pharmacol 1995;114:1351-8.
-
(1995)
Br J Pharmacol
, vol.114
, pp. 1351-1358
-
-
Alegret, M.1
Cerqueda, E.2
Ferrando, R.3
Vázquez, M.4
Sánchez, R.M.5
Adzet, T.6
-
32
-
-
0035254232
-
Differential induction of stearoyl-CoA desaturase and acyl-CoA oxidase genes by fibrates in HepG2 cells
-
Rodriguez C, Cabrero A, Roglans N, Adzet T, Sánchez RM, Vázquez M, et al. Differential induction of stearoyl-CoA desaturase and acyl-CoA oxidase genes by fibrates in HepG2 cells. Biochem Pharmacol 2001;61:357-64
-
(2001)
Biochem Pharmacol
, vol.61
, pp. 357-364
-
-
Rodriguez, C.1
Cabrero, A.2
Roglans, N.3
Adzet, T.4
Sánchez, R.M.5
Vázquez, M.6
-
33
-
-
0029077405
-
The regulation of stearoyl-CoA desaturase (SCD)
-
Ntambi JM. The regulation of stearoyl-CoA desaturase (SCD). Progr Lipid Res 1995;34:139-50.
-
(1995)
Progr Lipid Res
, vol.34
, pp. 139-150
-
-
Ntambi, J.M.1
-
34
-
-
0025311254
-
The effect of beclobric acid and clofibric acid on peroxisomal beta-oxidation and peroxisome proliferation in primary cultures of rat, monkey and human hepatocytes
-
Baluuboer BJ, van Holsteijn CW, Bleumink R, Mennes WC, van Pelt FN, Yap SH, et al. The effect of beclobric acid and clofibric acid on peroxisomal beta-oxidation and peroxisome proliferation in primary cultures of rat, monkey and human hepatocytes. Biochem Pharmacol 1990;40:521-528.
-
(1990)
Biochem Pharmacol
, vol.40
, pp. 521-528
-
-
Baluuboer, B.J.1
Van Holsteijn, C.W.2
Bleumink, R.3
Mennes, W.C.4
Van Pelt, F.N.5
Yap, S.H.6
-
35
-
-
0032102436
-
Effect of rodent hepatocarcinogenic peroxisome proliferators on fatty acyl-CoA oxidase, DNA synthesis, and apoptosis in cultured human and rat hepatocytes
-
Perrone CE, Shao L, Williams GM. Effect of rodent hepatocarcinogenic peroxisome proliferators on fatty acyl-CoA oxidase, DNA synthesis, and apoptosis in cultured human and rat hepatocytes. Toxicol Appl Pharmacol 1998;150:277-286.
-
(1998)
Toxicol Appl Pharmacol
, vol.150
, pp. 277-286
-
-
Perrone, C.E.1
Shao, L.2
Williams, G.M.3
-
36
-
-
0026661730
-
Induction of the peroxisome proliferator activated receptor by fenofibrate in rat liver
-
Gebel T, Arand M, Oesch F. Induction of the peroxisome proliferator activated receptor by fenofibrate in rat liver. FEBS Lett 1992;309:37-40.
-
(1992)
FEBS Lett
, vol.309
, pp. 37-40
-
-
Gebel, T.1
Arand, M.2
Oesch, F.3
-
37
-
-
0031589571
-
The peroxisome proliferator-activated receptor α (PPARα) regulates the plasma thiobarbituric acid-reactive substance (TBARS) level
-
Inoue I, Noji S, Shen MS, Takahashi K, Katayama S. The peroxisome proliferator-activated receptor α (PPARα) regulates the plasma thiobarbituric acid-reactive substance (TBARS) level. Biochem Biophys Res Commun 1997;237:606-10.
-
(1997)
Biochem Biophys Res Commun
, vol.237
, pp. 606-610
-
-
Inoue, I.1
Noji, S.2
Shen, M.S.3
Takahashi, K.4
Katayama, S.5
-
38
-
-
0035958960
-
Identification of peroxisome proliferator-responsive human genes by elevated expression of the peroxisome proliferator-activated receptor α in HepG2 cells
-
Hsu M-H, Savas U, Griffin KJ, Johnson EF. Identification of peroxisome proliferator-responsive human genes by elevated expression of the peroxisome proliferator-activated receptor α in HepG2 cells. J Biol Chem 2001;276:27950-8.
-
(2001)
J Biol Chem
, vol.276
, pp. 27950-27958
-
-
Hsu, M.-H.1
Savas, U.2
Griffin, K.J.3
Johnson, E.F.4
|