Mycobacterium bovis BCG producing Interleukin-18 increases antigen-specific gamma interferon production in mice

Infection and Immunity

Volumn 70, Issue 12, 2002, Pages 6549-6557

  Biet, Franck ^a   Kremer, Laurent ^a   Wolowczuk, Isabelle ^a   Delacre, Myriam ^a   Locht, Camille ^a  

^a INSTITUT PASTEUR DE LILLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BCG VACCINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEAT SHOCK PROTEIN 60; IMMUNOGLOBULIN G; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 18; MYCOBACTERIUM ANTIGEN; SIGNAL PEPTIDE;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GROWTH; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; HOST RESISTANCE; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNIZATION; IMMUNOMODULATION; IMMUNOTHERAPY; INTERFERON PRODUCTION; MACROPHAGE; MOUSE; MYCOBACTERIUM BOVIS; NATURAL KILLER CELL; NONHUMAN; OPERON; PRIORITY JOURNAL; PROMOTER REGION; PROPHYLAXIS; PROTEIN EXPRESSION; SPLEEN CELL; TH1 CELL; TISSUE CULTURE;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; FEMALE; HUMANS; IMMUNIZATION; INTERFERON TYPE II; INTERLEUKIN-18; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; MYCOBACTERIUM BOVIS; RECOMBINANT PROTEINS; TH1 CELLS; TRANSFECTION; TUBERCULOSIS; U937 CELLS;

EID: 0036893657     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.70.12.6549-6557.2002     Document Type: Article

References (50)

1. Bachelerie, F., J. Alcami, F. Arenzana-Seisdedos, and J. L. Virelizier. 1991. HIV enhancer activity perpetuated by NF-κB induction on infection of monocytes. Nature 350:709-712.
2. Baulard, A., V. Escuyer, N. Haddad, L. Kremer, C. Locht, and P. Berche. 1995. Mercury resistance as a selective marker for recombinant mycobacteria. Microbiology 141:1045-1050.
3. Baulard, A., C. Jourdan, A. Mercenier, and C. Locht. 1992. Rapid mycobacterial plasmid analysis by electroduction between Mycobacterium spp. and Escherichia coli. Nucleic Acids Res. 20:4105.
4. Baulard, A., L. Kremer, P. Supply, D. Vidaud, J. M. Bidart, D. Bellet, and C. Locht. 1996. A new series of mycobacterial expression vectors for the development of live recombinant vaccines. Gene 176:149-154.
5. Biet, F., C. Locht, and L. Kremer. 2002. Immunoregulatory functions of interleukin 18 and its role in defense against bacterial pathogens. J. Mol. Med. 80:147-162.
6. Carballido, J. M., N. Carballido-Perrig, G. Terres, C. H. Heusser, and K. Blaser. 1992. Bee venom phospholipase A2-specific T-cell clones from human allergic and non-allergic individuals: Cytokine patterns change in response to the antigen concentration. Eur. J. Immunol. 22:1357-1363.
7. Cooper, A. M., D. K. Dalton, T. A. Stewart, J. P. Griffin, D. G. Russell, and I. M. Orme. 1993. Disseminated tuberculosis in interferon gamma genedisrupted mice. J. Exp. Med. 178:2243-2247.
8. Cooper, A. M., J. Magram, J. Ferrante, and I. M. Orme. 1997. Interleukin 12 (IL-12) is crucial to the development of protective immunity in mice intravenously infected with Mycobacterium tuberculosis. J. Exp. Med. 186:39-45.
9. Dalton, D. K., S. Pitts-Meek, S. Keshav, I. S. Figari, A. Bradley, and T. A. Stewart. 1993. Multiple defects of immune cell function in mice with disrupted interferon-gamma genes. Science 259:1739-1742.
10. Dinarello, C. A. 1999. Interleukin-18. Methods 19:121-132.
11. Dinarello, C. A., D. Novick, A. J. Puren, G. Fantuzzi, L. Shapiro, H. Muhl, D. Y. Yoon, L. L. Reznikov, S. H. Kim, and M. Rubinstein. 1998. Overview of interleukin-18: More than an interferon-gamma inducing factor. J. Leukoc. Biol. 63:658-664.
12. Dybing, J. K., N. Walters, and D. W. Pascual. 1999. Role of endogenous interleukin-18 in resolving wild-type and attenuated Salmonella typhimurium infections. Infect. Immun. 67:6242-6248.
13. Erb, K. J., J. W. Holloway, A. Sobeck, H. Moll, and G. Le Gros. 1998. Infection of mice with Mycobacterium bovis Bacillus Calmette-Guerin (BCG) suppresses allergen-induced airway eosinophilia. J. Exp. Med. 187:561-569.
14. + T cells in asthma. Immunol. Cell. Biol. 74:206-208.
15. Fine, P. E. 1989. The BCG story: lessons from the past and implications for the future. Rev. Infect. Dis. 11(Suppl. 2):5353-5359.
16. Flynn, J. L., J. Chan, K. J. Triebold, D. K. Dalton, T. A. Stewart, and B. R. Bloom. 1993. An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection. J. Exp. Med. 178:2249-2254.
17. Gu, Y., K. Kuida, H. Tsutsui, G. Ku, K. Hsiao, M. A. Fleming, N. Hayashi, K. Higashino, H. Okamura, K. Nakanishi, M. Kurimoto, T. Tanimoto, R. A. Flavell, V. Sato, M. W. Harding, D. J. Livingston, and M. S. Su. 1997. Activation of interferon-gamma inducing factor mediated by interleukin-1β converting enzyme. Science 275:206-209.
18. Herr, H. W., V. P. Laudone, R. A. Badalament, H. F. Oettgen, P. C. Sogani, B. D. Freedman, M. R. Melamed, and W. F. Whitmore. 1988. Bacillus Calmette-Guerin therapy alters the progression of superficial bladder cancer. J. Clin. Oncol. 6:1450-1455.
19. Hofstra, C. L., I. Van Ark, G. Hofman, M. Kool, F. P. Nijkamp, and A. J. Van Oosterhout. 1998. Prevention of Th2-like cell responses by coadministration of IL-12 and IL-18 is associated with inhibition of antigen-induced airway hyperresponsiveness, eosinophilia, and serum IgE levels. J. Immunol. 161:5054-5060.
20. Kamijo, R., J. Le, D. Shapiro, E. A. Havell, S. Huang, M. Aguet, M. Bosland, and J. Vilcek. 1993. Mice that lack the interferon-gamma receptor have profoundly altered responses to infection with Bacillus Calmette-Guerin and subsequent challenge with lipopolysaccharide. J. Exp. Med. 178:1435-1440.
21. Kremer, L., A. Baulard, J. Estaquier, J. Content, A. Capron, and C. Locht. 1995. Analysis of the Mycobacterium tuberculosis 85A antigen promoter region. J. Bacteriol. 177:642-653.
22. Kremer, L., L. Dupre, I. Wolowczuk, and C. Locht. 1999. In vivo immunomodulation following intradermal injection with DNA encoding IL-18. J. Immunol. 163:3226-3231.
23. Kremer, L., J. Estaquier, I. Wolowczuk, F. Biet, J. C. Ameisen, and C. Locht. 2000. Ineffective cellular immune response associated with T-cell apoptosis in susceptible Mycobacterium bovis BCG-infected mice. Infect. Immun. 68:4264-4273.
24. Kremer, L., G. Riveau, A. Baulard, A. Capron, and C. Locht. 1996. Neutralizing antibody responses elicited in mice immunized with recombinant bacillus Calmette-Guerin producing the Schistosoma mansoni glutathione S-transferase. J. Immunol. 156:4309-4317.
25. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
26. Lamm, D. L. 1992. Long-term results of intravesical therapy for superficial bladder cancer. Urol. Clin. North. Am. 19:573-580.
27. Lamm, D. L. 1992. Optimal BCG treatment of superficial bladder cancer as defined by American trials. Eur. Urol. 21:12-16.
28. Liebermann, D. A., and B. Hoffman. 1998. MyD genes in negative growth control. Oncogene 17:3319-3329.
29. Lu, H., X. Yang, K. Takeda, D. Zhang, Y. Fan, M. Luo, C. Shen, S. Wang, S. Akira, and R. C. Brunham. 2000. Chlamydia trachomatis mouse pneumonitis lung infection in IL-18 and IL-12 knockout mice: IL-12 is dominant over IL-18 for protective immunity. Mol. Med. 6:604-612.
30. Luelmo, F. 1982. BCG vaccination. Am. Rev. Respir. Dis. 125:70-72.
31. Martinez-Pineiro, J. A., J. Jimenez Leon, L. Martinez-Pineiro, L. Fiter, J. A. Mosteiro, J. Navarro, M. J. Garcia Matres, and P. Carcamo. 1990. Bacillus Calmette-Guerin versus doxorubicin versus thiotepa: A randomized prospective study in 202 patients with superficial bladder cancer. J. Urol. 143:502-506.
32. Mastroeni, P., S. Clare, S. Khan, J. A. Harrison, C. E. Hormaeche, H. Okamura, M. Kurimoto, and G. Dougan. 1999. Interleukin 18 contributes to host resistance and gamma interferon production in mice infected with virulent Salmonella typhimurium. Infect. Immun. 67:478-483.
33. Matsumoto, S., K. Tsuji-Takayama, Y. Aizawa, K. Koide, M. Takeuchi, T. Ohta, and M. Kurimoto. 1997. Interleukin-18 activates NF-κB in murine T helper type 1 cells. Biochem. Biophys. Res. Commun. 234:454-457.
34. Matsuo, K., R. Yamaguchi, A. Yamazaki, H. Tasaka, and T. Yamada. 1988. Cloning and expression of the Mycobacterium bovis BCG gene for extracellular alpha antigen. J. Bacteriol. 170:3847-3854.
35. Micallef, M. J., T. Ohtsuki, K. Kohno, F. Tanabe, S. Ushio, M. Namba, T. Tanimoto, K. Torigoe, M. Fujii, M. Ikeda, S. Fukuda, and M. Kurimoto. 1996. Interferon-gamma-inducing factor enhances T helper 1 cytokine production by stimulated human T cells: Synergism with interleukin-12 for interferon-gamma production. Eur. J. Immunol. 26:1647-1651.
36. Morales, A., and J. C. Nickel. 1992. Immunotherapy for superficial bladder cancer: A developmental and clinical overview. Urol. Clin. North. Am. 19:549-556.
37. Murray, P. J., A. Aldovini, and R. A. Young. 1996. Manipulation and potentiation of antimycobacterial immunity using recombinant bacille CalmetteGuerin strains that secrete cytokines. Proc. Natl. Acad. Sci. USA 93:934-939.
38. Okamura, H., H. Tsutsi, T. Komatsu, M. Yutsudo, A. Hakura, T. Tanimoto, K. Torigoe, T. Okura, Y. Nukada, K. Hattori, et al. 1995. Cloning of a new cytokine that induces IFN-γ production by T cells. Nature 378:88-91.
39. Orme, I. M., P. Andersen, and W. H. Boom. 1993. T-cell response to Mycobacterium tuberculosis. J. Infect. Dis. 167:1481-1497.
40. Robinson, D., K. Shibuya, A. Mui, F. Zonin, E. Murphy, T. Sana, S. B. Hartley, S. Menon, R. Kastelein, F. Bazan, and A. O'Garra. 1997. IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NF-κB. Immunity 7:571-581.
41. Sambrook, J., F. E. Fritsch, and T. Maniatis. 1989. Molecular Cloning: A Laboratory Manual, 2nd Ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
42. Sansonetti, P. J., A. Phalipon, J. Arondel, K. Thirumalai, S. Banerjee, S. Akira, K. Takeda, and A. Zychlinsky. 2000. Caspase-1 activation of IL-1B and IL-18 are essential for Shigella flexneri-induced inflammation. Immunity 12:581-590.
43. Sauton, B. 1912. Sur la nutrition minérale du bacille tuberculeux. C. R. Hebd. Seances Acad. Sci. 155:860-861.
44. Schwartz, O., J. L. Virelizier, L. Montagnier, and U. Hazan. 1990. A microtransfection method using the luciferase-encoding reporter gene for the assay of human immunodeficiency virus LTR promoter activity. Gene 88:197-205.
45. Shirakawa, T., T. Enomoto, S. Shimazu, and J. M. Hopkin. 1997. The inverse association between tuberculin responses and atopic disorder. Science 275:77-79.
46. Sugawara, I., H. Yamada, H. Kaneko, S. Mizuno, K. Takeda, and S. Akira. 1999. Role of interleukin-18 (IL-18) in mycobacterial infection in IL-18-gene-disrupted mice. Infect. Immun. 67:2585-2589.
47. Takeda, K., H. Tsutsui, T. Yoshimoto, O. Adachi, N. Yoshida, T. Kishimoto, H. Okamura, K. Nakanishi, and S. Akira. 1998. Defective NK cell activity and Th1 response in IL-18-deficient mice. Immunity 8:383-390.
48. Torigoe, K., S. Ushio, T. Okura, S. Kobayashi, M. Taniai, T. Kunikata, T. Murakami, O. Sanou, H. Kojima, M. Fujii, T. Ohta, M. Ikeda, H. Ikegami, and M. Kurimoto. 1997. Purification and characterization of the human interleukin-18 receptor. J. Biol. Chem. 272:25737-25742.
49. Ushio, S., M. Namba, T. Okura, K. Hattori, Y. Nukada, K. Akita, F. Tanabe, K. Konishi, M. Micallef, M. Fujii, K. Torigoe, T. Tanimoto, S. Fukuda, M. Ikeda, H. Okamura, and M. Kurimoto. 1996. Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein. J. Immunol. 156:4274-4279.
50. Vidal, S. M., D. Malo, K. Vogan, E. Skamene, and P. Gros. 1993. Natural resistance to infection with intracellular parasites: Isolation of a candidate for Bcg. Cell 73:469-485.