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Volumn 81, Issue 4, 2002, Pages 177-184

Prognostic significance of p27KIP1 expression in resected non-small cell lung cancers: Analysis in combination with expressions of p16INK4A, pRB, and p53

Author keywords

NSCLC; P16; P27; P53; PRB; Prognosis

Indexed keywords

PROTEIN P16; PROTEIN P27; PROTEIN P53; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; PROTEIN P16INK4A; RETINOBLASTOMA PROTEIN; TUMOR SUPPRESSOR PROTEIN;

EID: 0036891964     PISSN: 00224790     EISSN: None     Source Type: Journal    
DOI: 10.1002/jso.10176     Document Type: Article
Times cited : (27)

References (33)
  • 1
    • 0026059515 scopus 로고
    • Tumor suppressor genes
    • Marshall CJ: Tumor suppressor genes. Cell 1994;64:313-326.
    • (1994) Cell , vol.64 , pp. 313-326
    • Marshall, C.J.1
  • 2
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr C: Cancer cell cycles. Science 1996;274:1672-1677.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.1
  • 3
    • 0028363519 scopus 로고
    • p27, a novel inhibitor of G1 cyclin-cdk protein kinase activity
    • Toyoshima H, Hunter T: p27, a novel inhibitor of G1 cyclin-cdk protein kinase activity. Cell 1994;78:67-74.
    • (1994) Cell , vol.78 , pp. 67-74
    • Toyoshima, H.1    Hunter, T.2
  • 4
    • 0029971843 scopus 로고    scopus 로고
    • Inversely correlated expression of p16 and Rb protein in non-small cell lung cancers: An immunohistochemical study
    • Sakaguchi M, Fujii Y, Hirabayashi H, et al.: Inversely correlated expression of p16 and Rb protein in non-small cell lung cancers: An immunohistochemical study. Int J Cancer 1996;65:442- 445.
    • (1996) Int J Cancer , vol.65 , pp. 442-445
    • Sakaguchi, M.1    Fujii, Y.2    Hirabayashi, H.3
  • 6
    • 0025265724 scopus 로고
    • Increased expression of mutant forms of p53 oncogene in primary lung cancer
    • Iggo R, Gatter K, Bartek J, et al.: Increased expression of mutant forms of p53 oncogene in primary lung cancer. Lancet 1990; 335:675-679.
    • (1990) Lancet , vol.335 , pp. 675-679
    • Iggo, R.1    Gatter, K.2    Bartek, J.3
  • 7
    • 0026737950 scopus 로고
    • Accumulation of p53 protein correlates with a poor prognosis in human lung cancer
    • Quinlan DC, Davidson AG, Summer CL, et al.: Accumulation of p53 protein correlates with a poor prognosis in human lung cancer. Cancer Res 1992;52:4828-4832.
    • (1992) Cancer Res , vol.52 , pp. 4828-4832
    • Quinlan, D.C.1    Davidson, A.G.2    Summer, C.L.3
  • 8
    • 14444268041 scopus 로고    scopus 로고
    • Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer
    • Esposito V, Baldi A, De-Luca A, et al.: Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer. Cancer Res 1997;57:3381-3385.
    • (1997) Cancer Res , vol.57 , pp. 3381-3385
    • Esposito, V.1    Baldi, A.2    De-Luca, A.3
  • 9
    • 0030765323 scopus 로고    scopus 로고
    • INK4A expression in nonsmall cell lung carcinoma
    • INK4A expression in nonsmall cell lung carcinoma. Cancer 1997;80:389-395.
    • (1997) Cancer , vol.80 , pp. 389-395
    • Taga, S.1    Osaki, T.2    Ohgami, A.3
  • 10
    • 0032956084 scopus 로고    scopus 로고
    • p16 inactivation in small sized lung adenocarcinoma: Its association with poor prognosis
    • Kawabuchi B, Moriyama S, Hironaka M, et al.: p16 inactivation in small sized lung adenocarcinoma: Its association with poor prognosis. Int J Cancer 1999;84:49-53.
    • (1999) Int J Cancer , vol.84 , pp. 49-53
    • Kawabuchi, B.1    Moriyama, S.2    Hironaka, M.3
  • 11
    • 0029658335 scopus 로고    scopus 로고
    • INK4 and retinoblastoma protein status in non-small cell lung cancer: Potential synergistic effect with altered p53 protein proliferative activity
    • INK4 and retinoblastoma protein status in non-small cell lung cancer: Potential synergistic effect with altered p53 protein proliferative activity. Cancer Res 1996;56:5557-5562.
    • (1996) Cancer Res , vol.56 , pp. 5557-5562
    • Kinoshita, I.1    Dosaka-Akita, H.2    Mishina, T.3
  • 12
    • 0035144783 scopus 로고    scopus 로고
    • Loss of p16 and/or pRb protein expression in NSCLC. An immunohistochemical and prognostic study
    • Chen JT, Chen YC, Chen CY, et al.: Loss of p16 and/or pRb protein expression in NSCLC. An immunohistochemical and prognostic study. Lung Cancer 2001;31:163-170.
    • (2001) Lung Cancer , vol.31 , pp. 163-170
    • Chen, J.T.1    Chen, Y.C.2    Chen, C.Y.3
  • 13
    • 0028198531 scopus 로고
    • Altered retinoblastoma protein expression and expression and prognosis in early stage non-small-cell lung cancer
    • Xu H, Quinlan DC, Davidson AG, et al.: Altered retinoblastoma protein expression and expression and prognosis in early stage non-small-cell lung cancer. J Natl Cancer Inst 1994;86:695-699.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 695-699
    • Xu, H.1    Quinlan, D.C.2    Davidson, A.G.3
  • 14
    • 0032926002 scopus 로고    scopus 로고
    • Correlation of abnormal RB, p16, and p53 expression with 3p loss of heterozygosity, other genetic abnormalities, and clinical features in 103 primary non-small cell lung cancers
    • Geradts J, Fong KM, Zimmerman PV, et al.: Correlation of abnormal RB, p16, and p53 expression with 3p loss of heterozygosity, other genetic abnormalities, and clinical features in 103 primary non-small cell lung cancers. Clin Cancer Res 1999;5: 791-800.
    • (1999) Clin Cancer Res , vol.5 , pp. 791-800
    • Geradts, J.1    Fong, K.M.2    Zimmerman, P.V.3
  • 15
    • 0029113707 scopus 로고
    • Expression of p53 oncoprotein in non-small-cell lung cancer: A favorable prognostic factor
    • Lee JS, Yoon A, Kalapurakal SK, et al.: Expression of p53 oncoprotein in non-small-cell lung cancer: A favorable prognostic factor. J Clin Oncol 1995;13:1893-1903.
    • (1995) J Clin Oncol , vol.13 , pp. 1893-1903
    • Lee, J.S.1    Yoon, A.2    Kalapurakal, S.K.3
  • 16
    • 0033490402 scopus 로고    scopus 로고
    • The cyclin-dependent kinase inhibitor p27 as a prognostic factor in advanced non-small cell lung cancer: Its immunohistochemical evaluation using biopsy specimens
    • Ishihara S, Minato K, Hoshino H, et al.: The cyclin-dependent kinase inhibitor p27 as a prognostic factor in advanced non-small cell lung cancer: Its immunohistochemical evaluation using biopsy specimens. Lung Cancer 1999;26:187-194.
    • (1999) Lung Cancer , vol.26 , pp. 187-194
    • Ishihara, S.1    Minato, K.2    Hoshino, H.3
  • 17
    • 0033083047 scopus 로고    scopus 로고
    • Kip1 in non-small cell lung carcinoma: A prognostic factor independent of Ras
    • Kip1 in non-small cell lung carcinoma: A prognostic factor independent of Ras. Cancer Res 1999;59: 684-688.
    • (1999) Cancer Res , vol.59 , pp. 684-688
    • Catzavelos, C.1    Tsao, M.S.2    DeBoer, G.3
  • 18
    • 0031895370 scopus 로고    scopus 로고
    • Disruption of the RB pathway and cell-proliferative activity in non-small-cell lung cancers
    • Tanaka H, Fujii Y, Hirabayashi H, et al.: Disruption of the RB pathway and cell-proliferative activity in non-small-cell lung cancers. Int J Cancer 1998;79:111-115.
    • (1998) Int J Cancer , vol.79 , pp. 111-115
    • Tanaka, H.1    Fujii, Y.2    Hirabayashi, H.3
  • 19
    • 16944363001 scopus 로고    scopus 로고
    • KIP1 protein: Prognostic implications in primary breast cancer
    • KIP1 protein: Prognostic implications in primary breast cancer. Nat Med 1997;3:227-230.
    • (1997) Nat Med , vol.3 , pp. 227-230
    • Catzavelos, C.1    Bhattacharya, N.2    Ung, Y.C.3
  • 20
    • 0031048236 scopus 로고    scopus 로고
    • Increased proteasome- dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas
    • Loda M, Cukor B, Tam SW, et al.: Increased proteasome- dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nat Med 1997;3:231-234.
    • (1997) Nat Med , vol.3 , pp. 231-234
    • Loda, M.1    Cukor, B.2    Tam, S.W.3
  • 21
    • 0034780882 scopus 로고    scopus 로고
    • Cyclin D1, p16 and retino-blastoma gene product expression as a predictor for prognosis in non-small cell lung cancer at stage I and II
    • Jin M, Inoue S, Umemura T, et al.: Cyclin D1, p16 and retino-blastoma gene product expression as a predictor for prognosis in non-small cell lung cancer at stage I and II. Lung Cancer 2001;34:207-218.
    • (2001) Lung Cancer , vol.34 , pp. 207-218
    • Jin, M.1    Inoue, S.2    Umemura, T.3
  • 22
    • 0024452546 scopus 로고
    • p53: A frequent target for genetic abnormalities in lung cancer
    • Takahashi T, Nau MM, Chiba I, et al.: p53: A frequent target for genetic abnormalities in lung cancer. Science 1989;246:491-494.
    • (1989) Science , vol.246 , pp. 491-494
    • Takahashi, T.1    Nau, M.M.2    Chiba, I.3
  • 23
    • 9044231367 scopus 로고    scopus 로고
    • Prognostic significance of abnormal p53 accumulation in primary, resected non-small-cell lung cancers
    • Nishio M, Koshikawa T, Kuronishi T, et al.: Prognostic significance of abnormal p53 accumulation in primary, resected non-small-cell lung cancers. J Clin Oncol 1996;14:497-502.
    • (1996) J Clin Oncol , vol.14 , pp. 497-502
    • Nishio, M.1    Koshikawa, T.2    Kuronishi, T.3
  • 25
    • 0035181301 scopus 로고    scopus 로고
    • Prognostic molecular makers in non-small cell lung cancer
    • Niklifiski J, Nikliñska W, Laudanski J, et al.: Prognostic molecular makers in non-small cell lung cancer. Lung Cancer 2001;34:S53-S58.
    • (2001) Lung Cancer , vol.34
    • Niklifiski, J.1    Nikliñska, W.2    Laudanski, J.3
  • 26
    • 0033765491 scopus 로고    scopus 로고
    • Prognostic significance of p53 alterations in patients with non-small cell lung cancer: A meta-analysis
    • Mitsudomi T, Hamajima N, Ogawa M, et al.: Prognostic significance of p53 alterations in patients with non-small cell lung cancer: A meta-analysis. Clin Cancer Res 2000;6:4055-4063.
    • (2000) Clin Cancer Res , vol.6 , pp. 4055-4063
    • Mitsudomi, T.1    Hamajima, N.2    Ogawa, M.3
  • 27
    • 18744431008 scopus 로고    scopus 로고
    • Biological prognostic factors for early stage completely resected non-small cell lung cancer
    • Cagini L, Monacelli M, Giustozzi G, et al.: Biological prognostic factors for early stage completely resected non-small cell lung cancer. J Surg Oncol 2000;74:53-60.
    • (2000) J Surg Oncol , vol.74 , pp. 53-60
    • Cagini, L.1    Monacelli, M.2    Giustozzi, G.3
  • 28
    • 0029024015 scopus 로고
    • Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
    • Pagano M, Tam SW, Theodoras AM, et al.: Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science 1995;269:683-685.
    • (1995) Science , vol.269 , pp. 683-685
    • Pagano, M.1    Tam, S.W.2    Theodoras, A.M.3
  • 29
    • 0028986932 scopus 로고
    • p27: Chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors
    • Ponce-Castaneda MV, Lee MH, Latres E, et al.: p27: Chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors. Cancer Res 1995;55:1211-1214.
    • (1995) Cancer Res , vol.55 , pp. 1211-1214
    • Ponce-Castaneda, M.V.1    Lee, M.H.2    Latres, E.3
  • 30
    • 0034848442 scopus 로고    scopus 로고
    • Kip1 correlates with a shortened survival in non-small cell cancer
    • Kip1 correlates with a shortened survival in non-small cell cancer. Lung Cancer 2001;34:83-90.
    • (2001) Lung Cancer , vol.34 , pp. 83-90
    • Tsukamoto, S.1    Sugio, K.2    Sakada, T.3
  • 31
    • 0033998106 scopus 로고    scopus 로고
    • Loss of p27 (KIP1) expression predicts poor prognosis in patients with esophageal squamous cell carcinoma
    • Shamma A, Doki Y, Tsujinaka T, et al.: Loss of p27 (KIP1) expression predicts poor prognosis in patients with esophageal squamous cell carcinoma. Oncology 2000;58:152-158.
    • (2000) Oncology , vol.58 , pp. 152-158
    • Shamma, A.1    Doki, Y.2    Tsujinaka, T.3
  • 32
    • 0033626566 scopus 로고    scopus 로고
    • Prognostic significance of p27 Kip1 protein and Ki-67 growth fraction in non-small cell cancers
    • Hommura F, Dosaka-Akita H, Mishima T, et al.: Prognostic significance of p27 Kip1 protein and Ki-67 growth fraction in non-small cell cancers. Clin Cancer Res 2000;6:4073-4081.
    • (2000) Clin Cancer Res , vol.6 , pp. 4073-4081
    • Hommura, F.1    Dosaka-Akita, H.2    Mishima, T.3
  • 33
    • 0034854016 scopus 로고    scopus 로고
    • High cyclin E and low p27/ Kip1 expressions are potentially poor prognostic factors in lung adenocarinoma patients
    • Hayashi H, Ogawa N, Ishiwa N, et al.: High cyclin E and low p27/ Kip1 expressions are potentially poor prognostic factors in lung adenocarinoma patients. Lung Cancer 2001;34:59-65,
    • (2001) Lung Cancer , vol.34 , pp. 59-65
    • Hayashi, H.1    Ogawa, N.2    Ishiwa, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.