Cutting-edge technology IV. Genomic engineering for studies of the gastrointestinal tract in mice

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 283, Issue 6 46-6, 2002, Pages

  Bullard, Daniel C ^a   Weaver, Casey T ^b,c  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b University of Alabama at Birmingham   (United States)

^c NONE   (United States)

Author keywords

Continual gene targeting; Cre loxP; Intestines; N ethyl N nitrosourea mutagenesis; Tissue specific promoters

Indexed keywords

ARTICLE; CELL LINEAGE; GASTROINTESTINAL MUCOSA; GASTROINTESTINAL TRACT; GENETIC ENGINEERING; GENETIC MANIPULATION; IMMUNE SYSTEM; INTESTINE EPITHELIUM; INTESTINE FLORA; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TECHNOLOGY;

EID: 0036890441     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00035.2002     Document Type: Article

References (25)

1. Cohn S, Simon T, Roth K, Birkenmeier E, and Gordon J. Use of transgenic mice to map cis-acting elements in the intestinal fatty acid binding protein gene (Fabpi) that control its cell lineage-specific and regional patterns of expression along the duodenal-colonic and crypt-villus axes of the gut epithelium. J Cell Biol 119: 27-44, 1992.
2. Copeland N, Jenkins N, and Court D. Recombineering: A powerful new tool for mouse functional genomics. Nature Rev Genet 2: 769-779, 2001.
3. Farmer M, Sundberg J, Bristol I, Churchill G, Li R, Elson C, and Leiter E. A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice. Proc Natl Acad Sci USA 98: 13820-13825, 2001.
4. Feil R, Brocard J, Mascrez B, LeMeur M, Metzger D, and Chambon P. Ligand-activated site-specific recombination in mice. Proc Natl Acad Sci USA 93: 10887-10890, 1996.
5. Gossen M and Bujard H. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 89: 5547-5551, 1992.
6. Gossen M, Freundlieb S, Bender G, Muller G, Hillen W, and Bujard H. Transcriptional activation by tetracyclines in mammalian cells. Science 268: 1766-1769, 1995.
7. T2) in adipocytes. Proc Natl Acad Sci USA 98: 224-228, 2000.
8. Joyner A. Gene Targeting: A Practical Approach. New York: Oxford University Press, 1993.
9. Kistner A, Gossen M, Zimmerman F, Jerecic J, Ullmer C, Lubbert H, and Bujard H. Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice. Proc Natl Acad Sci USA 93: 10933-10938, 1996.
10. Lewandoski M. Conditional control of gene expression in the mouse. Nat Rev Genet 2: 743-755, 2001.
11. Markel P, Shu P, Ebeling C, Carlson G, Nagle D, Smutko J, and Moore K. Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains. Nat Genet 17: 280-284, 1997.
12. Nadeau J. Modifier genes in mice and humans. Nat Rev Genet 2: 165-174, 2001.
13. Nagy A. Cre recombinase: The universal reagent for genome tailoring. G Chir 26: 99-109, 2000.
14. Nelms K and Goodnow C. Genome-wide ENU mutagenesis to reveal immune regulators. Immunity 15: 409-418, 2001.
15. No D, Yao TP, and Evans R. Ecdysone-inducible gene expression in mammaliancells and transgenic mice. Proc Natl Acad Sci USA 93: 3346-3351, 1996.
16. Ryding A, Sharp M, and Mullins J. Conditional transgenic technologies. J Endocrinol 171: 1-14, 2001.
17. Saam J and Gordon J. Inducible gene knockouts in the small intestinal and colonic epithelium. J Biol Chem 274: 38071-38082, 1999.
18. Shibata H, Toyama K, Shioya H, Ito M, Hirota M, Hasegawa S, Matsumoto H, Takano H, Akiyama T, Toyoshima K, Kanamaru R, Kanegae Y, Saito I, Nakamura Y, Shiba K, and Noda T. Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene. Science 278: 120-123, 1997.
19. Simon T, Cho A, Tso P, and Gordon J. Suppressor and activator functions mediated by a repeated heptad sequence in the liver fatty acid-binding protein gene (Fabpl). J Biol Chem 272: 10652-10663, 1997.
20. Simon T, Roberts L, and Gordon J. A 20-nucleotide element in the intestinal fatty acid binding protein gene modulates its cell lineage-specific, differentiation-dependent, and cephalocaudal patterns of expression in transgenic mice. Proc Natl Acad Sci USA 92: 8685-8689, 1995.
21. Simon T, Roth K, and Gordon J. Use of transgenic mice to map cis-acting elements in the liver fatty acid-binding protein gene (Fabpl) that regulate its cell lineage-specific, differentiation-dependent, and spatial patterns of expression in the gut epithelium and in the liver acinus. J Biol Chem 268: 18345-18358, 1993.
22. Sweetser D, Hauft S, Hoppe P, Birkenmeier E, and Gordon J. Transgenic mice containing intestinal fatty acid-binding protein-human growth hormone fusion genes exhibit correct regional and cell-specific expression of the reporter gene in their small intestine. Proc Natl Acad Sci USA 85: 9611-9615, 1988.
23. Tsai S, O'Malley B, DeMayo F, Wang Y, and Chua S. A novel RU486 inducible system for the activation and repression of genes. Adv Drug Delivery Res 30: 23-31, 1998.
24. Wakeland E, Morel L, Achey K, Yui M, and Longmate J. Speed congenics: a classic technique in the fast lane (relatively speaking). Immunol Today 18: 472-477, 1997.
25. Yu D, Ellis H, Lee EC, Jenkins N, Copeland N, and Court D. An efficient recombination system for chromosome engineering in Escherichia coll. Proc Natl Acad Sci USA 97: 5978-5983, 2000.