Acute and delayed effects of phencyclidine upon mRNA levels of markers of glutamatergic and GABAergic neurotransmitter function in the rat brain

Synapse

Volumn 46, Issue 3, 2002, Pages 206-214

  Cochran, Susan M ^a   Fujimura, Masatake ^b   Morris, Brian J ^a,c   Pratt, Judith A ^a,d  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

^d UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

CaMKII ; Cortex; Homer 1a; Hsp 70; Parvalbumin; Schizophrenia; Thalamus

Indexed keywords

4 AMINOBUTYRIC ACID; AMPA RECEPTOR; BIOLOGICAL MARKER; GLUTAMATE RECEPTOR; GLUTAMIC ACID; HEAT SHOCK PROTEIN 70; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PARVALBUMIN; PHENCYCLIDINE; PROTEIN KINASE (CALCIUM,CALMODULIN) II;

ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN CORTEX; GABAERGIC TRANSMISSION; GENE EXPRESSION; HIPPOCAMPUS; IMMEDIATE EARLY GENE; MALE; NEUROTOXICITY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SCHIZOPHRENIA; SUBSTANTIA NIGRA; THALAMUS;

ANIMALS; BRAIN; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CARRIER PROTEINS; DRUG ADMINISTRATION SCHEDULE; EXCITATORY AMINO ACID ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; GENE EXPRESSION; GLUTAMIC ACID; HSP70 HEAT-SHOCK PROTEINS; IN SITU HYBRIDIZATION; MALE; NEUROPEPTIDES; PARVALBUMINS; PHENCYCLIDINE; RATS; RATS, LONG-EVANS; RNA, MESSENGER; TIME FACTORS;

EID: 0036887681     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/syn.10126     Document Type: Article

References (60)

1. Allen RM, Young SJ. 1978. Phencyclidine-induced psychosis. Am J Psychiatry 135:1081-1084.
2. Andreasen NC, O'Leary DS, Cizadlo T, Arndt S, Rezai K, Ponto LL, Watkins GL, Hichwa RD. 1996 Schizophrenia and cognitive dysmetria: a positron-emission tomography study of dysfunctional prefrontal-thalamic-cerebellar circuitry. Proc Natl Acad Sci USA 93:9985-9990.
3. Barria A, Muller D, Derkach V, Griffith LC, Soderling TR. 1997. Regulatory phosphorylation of AMPA-type glutamate receptors by CaM-KII during long-term potentiation. Science 276:2042-2045.
4. Beasley CL, Reynolds GP. 1997. Parvalbumin-immunoreactive neurons are reduced in the prefrontal cortex of schizophrenics. Schizophr Res 24:349-355.
5. Benes FM, Vincent SL, Marie A, Khan Y. 1996. Up-regulation of GABAA receptor binding on neurons of the prefrontal cortex in schizophrenic subjects. Neuroscience 75:1021-1031.
6. Benfenati F, Valtorta F, Rubenstein JL, Gorelick FS, Greengard P, Czernik AJ. 1992. Synaptic vesicle-associated Ca2+/calmodulin-dependent protein kinase II is a binding protein for synapsin I. Nature 359:417-420.
7. Blumcke I, Weruaga E, Kasas S, Hendrickson AE, Celio MR. 1994. Discrete reduction patterns of parvalbumin and calbindin D-28k immunoreactivity in the dorsal lateral geniculate nucleus and the striate cortex of adult macaque monkeys after monocular enucleation. Vis Neurosci 11:1-11.
8. Brakeman PR, Lanahan AA, O'Brien R, Roche K, Barnes CA, Huganir RL, Worley PF. 1997. Homer: a protein that selectively binds metabotropic glutamate receptors. Nature 386:284-288.
9. Celio MR. 1990. Calbindin D-28k and parvalbumin in the rat nervous system. Neuroscience 35:375-475.
10. Cellerino A, Siciliano R, Domenici L, Maffei L. 1992. Parvalbumin immunoreactivity: a reliable marker for the effects of monocular deprivation in the rat visual cortex. Neuroscience 51:749-753.
11. Chapman PF, Frenguelli BG, Smith A, Chen CM, Silva AJ. 1995. The alpha-Ca2+/calmodulin kinase II: a bidirectional modulator of presynaptic plasticity. Neuron 14:591-597.
12. Cochran SM, McKerchar CE, Pratt JA, Morris BJ. 2001. Chronic intermittent exposure to phencyclidine induces metabolic hypofunction and decreased parvalbumin expression. Soc Neurosci Abstr 663.1.
13. Conde F, Lund JS, Jacobowitz DM, Baimbridge KG, Lewis DA. 1994. Local circuit neurons immunoreactive for calretinin, calbindin D-28k or parvalbumin in monkey prefrontal cortex: distribution and morphology. J Comp Neurol 341:95-116.
14. Cosgrove J, Newell TG. 1991. Recovery of neuropsychological functions during reduction in use of phencyclidine. J Clin Psychol 47:159-169.
15. Crespo'Facorro B, Paradiso S, Andreasen NC, O'Leary DS, Watkins GL, Boles Ponto LL, Hichwa RD. 1999. Recalling word lists reveals cognitive dysmetria in schizophrenia: a positron emission tomography study. Am J Psychiatry 156:386-392.
16. Danos P, Baumann B, Bernstein H-G, Franz M, Stauch R, Northoff G, Krell D, Falkai P, Bogerts B. 1998. Schizophrenia and anteroventral thalamic nucleus: selective decrease of parvalbumin-immunoreactive thalamocortical projection neurons. Psychiat Res 82:1-10.
17. Gao XM, Shirakawa O, Du F, Tamminga CA. 1993. Delayed regional metabolic actions of phencyclidine. Eur J Pharmacol 241:7-15.
18. Gao XM, Hashimoto T, Tamminga CA. 1998. Phencyclidine (PCP) and dizocilpine (MK801) exert time-dependent effects on the expression of immediate early genes in rat brain. Synapse 29:14-28.
19. Hashimoto K, Tomitaka S, Narita N, Minabe Y, Iyo M, Fukui S. 1996. Induction of heat shock protein (HSP)-70 in posterior cingulate and retrosplenial cortex of rat brain by dizocilpine and phencyclidine: lack of protective effects of s receptor ligands. Addict Biol 1:61-70.
20. Hashimoto K, Tomitaka S, Bi Y, Narita N, Minabe Y, Iyo M. 1997. Rolipram, a selective phosphodiesterase type-IV inhibitor, prevents induction of heat shock protein HSP-70 and hsp-70 mRNA in rat retrosplenial cortex by the NMDA receptor antagonist dizocilpine. Eur J Neurosci 9:1891-1901.
21. Huntsman MM, Tran BV, Potkin SG, Bunney WE, Jones EG. 1998. Altered ratios of alternatively spliced long and short gamma2 subunit mRNAs of the gamma-amino butyrate type A receptor in prefrontal cortex of schizophrenics. Proc Natl Acad Sci USA 95:15066-15071.
22. Johnston HM, Morris BJ. 1995. N-methyl-D-aspartate and nitric oxide regulate the expression of calcium/calmodulin-dependent protein kinase II in the hippocampal dentate gyrus. Mol Brain Res 31:141-150.
23. Jones EG. 1997. Cortical development and thalamic pathology in schizophrenia. Schizophr Bull 23:483-501.
24. Kalus P, Senitz D, Lauer M, Beckmann H. 1999. Inhibitory cartridge synapses in the anterior cingulate cortex of schizophrenics. J Neural Trans 106:763-771.
25. Kato A, Ozawa F, Saitoh Y, Fukazawa Y, Sugiyama H, Inokuchi K. 1998. Novel members of the Vesl/Homer family of PDZ proteins that bind metabotropic glutamate receptors. J Biol Chem 273:23969-23975.
26. Kelly PT, McGuinness TL, Greengard P. 1984. Evidence that the major postsynaptic density protein is a component of a Ca2+/calmodulin-dependent protein kinase. Proc Natl Acad Sci USA 81:945-949.
27. Kennedy MB, Bennett MK, Erondu NE. 1983. Biochemical and immunochemical evidence that the 'major postsynaptic density protein' is a subunit of a calmodulin-dependent protein kinase. Proc Natl Acad Sci USA 80:7357-7361.
28. Krystal JH, Karper LP, Seibyl JP, Freeman GK, Delaney R, Bremner JD, Heninger GR, Bowers MB, Charney DS 1994. Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Arch Gen Psychiatry 51:199-214.
29. Lahti AC, Koffel B, LaPorte D, Tamminga CA. 1995. Subanesthetic doses of ketamine stimulate psychosis in schizophrenia. Neuropsychopharmacology 13:9-19.
30. Lewis DA. 1998. Chandelier cells: shedding light on altered cortical circuitry in schizophrenia. Mol Psychiatry 3:468-471.
31. Lewis DA. 2000. GABAergic local circuit neurons and prefrontal cortical dysfunction in schizophrenia. Brain Res Rev 31:270-276.
32. Lin CR, Kapiloff MS, Durgerian S, Tatemoto K, Russo AF, Hanson P, Schulman H, Rosenfeld MG. 1987. Molecular cloning of a brain-specific calcium/calmodulin-dependent protein kinase. Proc Natl Acad Sci USA 84:5962-5966.
33. Lisman J, Malenka RC, Nicoll RA, Malinow R. 1997. Learning mechanisms: the case for CaM-KII. Science 276:2001-2002.
34. Longo FM, Wang S, Narasimhan P, Zhang JS, Chen J, Massa SM, Sharp FR. 1993. cDNA cloning and expression of stress-inducible rat hsp70 in normal and injured rat brain. J Neurosci Res 36:325-335.
35. Luby ED, Cohen BD, Rosenbaum G, Gottlieb JS, Kelly R. 1959. Study of a new schizophrenomimetic drug-sernyl. Arch Neurol Psych 81:363-369.
36. Malhotra AK, Pinals DA, Adler CM, Elman I, Clifton A, Pickar D, Breier A. 1997. Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics. Neuropsychopharmacology 17:141-150.
37. Nakamura Y, Kitani T, Okuno S, Otake K, Sato F, Fujisawa H. 2000. Immunohistochemical study of the distribution of Ca(2+)/calmodulin-dependent protein kinase phosphatase in the rat central nervous system. Mol Brain Res 77:76-94.
38. Ohnuma T, Augood SJ, Arai H, McKenna PJ, Emson PC. 1999. Measurement of GABAergic parameters in the prefrontal cortex in schizophrenia: focus on GABA content, GABA(A) receptor alpha-1 subunit messenger RNA and human GABA transporter-1 (HGAT-1) messenger RNA expression. Neuroscience 93:441-448.
39. Olney JW, Labruyere J, Price MT. 1989. Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs. Science 244:1360-1362.
40. Olney JW, Labruyere J, Wang G, Wozniak DF, Price MT. 1991. NMDA antagonist neurotoxicity: mechanism and prevention. Science 254:1515-1518.
41. Paxinos G, Watson C. 1998. The rat brain in stereotaxic coordinates, 4th ed. Sydney: Academic Press.
42. Philpot BD, Lim JH, Brunjes PC. 1997. Activity-dependent regulation of calcium-binding proteins in the developing rat olfactory bulb. J Comp Neurol 387:12-26.
43. Popken GJ, Bunney Jr WE, Potkin SG, Jones EG. 1999. GABAergic and glutamatergic mRNA expression in thalamic nuclei of schizophrenics. Soc Neurosci Abstr 329.1.
44. Porter LL, Rizzo E, Hornung JP. 1999. Dopamine affects parvalbumin expression during cortical development in vitro. J Neurosci 19:8990-9003.
45. Price JL. 1995. Thalamus. In: Paxinos G, editor. The rat nervous system, 2nd ed. Sydney: Academic Press. p 629-648.
46. Rainey JM J, Crowder MK. 1975. Prolonged psychosis attributed to phencyclidine: report of three cases. Am J Psychiatry 132:1076-1078.
47. Roberts LA, Higgins MJ, O'Shaughnessy CT, Stone TW, Morris BJ. 1996. Changes in hippocampal gene expression associated with the induction of long-term potentiation. Mol Brain Res 42:123-127.
48. Roberts LA, Large CH, Higgins MJ, Stone TW, O'Shaughnessy CT, Morris BJ. 1998. Increased expression of dendritic mRNAs following the induction of long-term potentiation. Mol Brain Res 56:38-44.
49. Rongo C, Kaplan JM. 1999. CaMKII regulates the density of central glutamatergic synapses in vivo. Nature 402:195-199.
50. Sharp FR, Jasper P, Hall J, Noble L, Sagar SM. 1991. MK-801 and ketamine induce heat shock protein HSP72 in injured neurons in posterior cingulate and retrosplenial cortex. Ann Neurol 30:801-809.
51. Sharp FR, Butman M, Koistinaho J, Aardalen K, Nakki R, Massa SM, Swanson RA, Sagar SM. 1994. Phencyclidine induction of the hsp 70 stress gene in injured pyramidal neurons is mediated via multiple receptors and voltage gated calcium channels. Neuroscience 62:1079-1092.
52. Sharp FR, Tomitaka M, Bernaudin M, Tomitaka S. 2001. Psychosis: pathological activation of limbic thalamocortical circuits by psychotomimetics and schizophrenia. TINS 24:330-334.
53. Sun J, Tadokoro S, Imanaka T, Murakami SD, Nakamura M, Kashiwada K, Ko J, Nishida W, Sobue K. 1998. Isolation of PSD-Zip45, a novel Homer/vesl family protein containing leucine zipper motifs, from rat brain. FEBS Lett 437:304-308.
54. Tamminga CA. 1998. Schizophrenia and glutamatergic transmission. Crit Rev Neurobiol 12:21-36.
55. Thomas KL, Laroche S, Errington ML, Bliss TV, Hunt SP. 1994. Spatial and temporal changes in signal transduction pathways during LTP. Neuron 13:737-745.
56. Tomitaka SI, Hashimoto K, Narita N, Minabe Y, Tamura A. 1997. Regionally different effects of scopolamine on NMDA antagonist-induced heat shock protein HSP70. Brain Res 763:255-258.
57. Tononi G, Edelman GM. 2000. Schizophrenia and the mechanisms of conscious integration. Brain Res Rev 31:391-400.
58. Tu JC, Xiao B, Yuan JP, Lanahan AA, Leoffert K, Li M, Linden DJ, Worley PF. 1998. Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IP3 receptors. Neuron 21:717-726.
59. Tu JC, Xiao B, Naisbitt S, Yuan JP, Petralia RS, Brakeman P, Doan A, Aakalu VK, Lanahan AA, Sheng M, Worley PF. 1999. Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins. Neuron 23:583-592.
60. Xiao B, Tu JC, Petralia RS, Yuan JP, Doan A, Breder CD, Ruggiero A, Lanahan AA, Wenthold RJ, Worley PF. 1998. Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins. Neuron 21: 707-716.