메뉴 건너뛰기




Volumn 34, Issue 12, 2002, Pages 1557-1570

The role of oxidised regenerated cellulose/collagen in wound repair: Effects in vitro on fibroblast biology and in vivo in a model of compromised healing

Author keywords

Biomaterial; Delayed wound healing; Diabetes; Fibroblast migration proliferation

Indexed keywords

COLLAGEN; OXIDIZED REGENERATED CELLULOSE; OXIDIZED CELLULOSE;

EID: 0036887582     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1357-2725(02)00062-6     Document Type: Article
Times cited : (101)

References (67)
  • 1
    • 0010689151 scopus 로고    scopus 로고
    • Growth factors
    • M. Miller, D. Glover (Eds.), N.T. Books, London
    • J. Hart, Growth factors, in: M. Miller, D. Glover (Eds.), Wound Management Theory and Practice, N.T. Books, London, 2000, pp. 153-169.
    • (2000) Wound Management Theory and Practice , pp. 153-169
    • Hart, J.1
  • 3
    • 0032107248 scopus 로고    scopus 로고
    • Regenerative biology and engineering: Strategies for tissue restoration
    • Stocum D.L. Regenerative biology and engineering: strategies for tissue restoration. Wound Rep. Reg. 6:1998;276-290.
    • (1998) Wound Rep. Reg. , vol.6 , pp. 276-290
    • Stocum, D.L.1
  • 4
    • 0030033745 scopus 로고    scopus 로고
    • Venous ulcer fibroblasts compared with normal fibroblasts show differences in collagen but not fibronectin production under both normal and hypoxic conditions
    • Herrick S.E., Ireland G.W., Simon D., McCollum C.N., Ferguson M.W. Venous ulcer fibroblasts compared with normal fibroblasts show differences in collagen but not fibronectin production under both normal and hypoxic conditions. J. Invest. Dermatol. 106:1996;187-193.
    • (1996) J. Invest. Dermatol. , vol.106 , pp. 187-193
    • Herrick, S.E.1    Ireland, G.W.2    Simon, D.3    McCollum, C.N.4    Ferguson, M.W.5
  • 5
    • 0031435029 scopus 로고    scopus 로고
    • Dermal fibroblasts from venous ulcers are unresponsive to the action of transforming growth factor-β 1
    • Hasan A., Murata H., Falabella A., Ochoa S., Zhou L., Badiavas E., Falanga V. Dermal fibroblasts from venous ulcers are unresponsive to the action of transforming growth factor-β 1. J. Dermatol. Sci. 16:1997;59-66.
    • (1997) J. Dermatol. Sci. , vol.16 , pp. 59-66
    • Hasan, A.1    Murata, H.2    Falabella, A.3    Ochoa, S.4    Zhou, L.5    Badiavas, E.6    Falanga, V.7
  • 6
    • 0027333290 scopus 로고
    • TGF-β and TGF-β type II receptor in human epidermis: Differential expression in acute and chronic skin wounds
    • Schmid P., Cox D., Bilbe G., McMaster G., Morrison C., Stahelin H., Luscher N., Seiler W. TGF-β and TGF-β type II receptor in human epidermis: differential expression in acute and chronic skin wounds. J. Pathol. 171:1993;191-197.
    • (1993) J. Pathol. , vol.171 , pp. 191-197
    • Schmid, P.1    Cox, D.2    Bilbe, G.3    McMaster, G.4    Morrison, C.5    Stahelin, H.6    Luscher, N.7    Seiler, W.8
  • 7
    • 0029149872 scopus 로고
    • Detection of platelet-derived growth factor (PDGF)-AA in actively healing human wounds treated with recombinant PDGF-BB and absence of PDGF in chronic non-healing wounds
    • Pierce G.F., Tarpley J.E., Tseng J., Bready J., Chang D., Kenney W.C., Rudolph R., Robson M.C., Vande Berg J., Reid P. Detection of platelet-derived growth factor (PDGF)-AA in actively healing human wounds treated with recombinant PDGF-BB and absence of PDGF in chronic non-healing wounds. J. Clin. Invest. 96:1995;1336-1350.
    • (1995) J. Clin. Invest. , vol.96 , pp. 1336-1350
    • Pierce, G.F.1    Tarpley, J.E.2    Tseng, J.3    Bready, J.4    Chang, D.5    Kenney, W.C.6    Rudolph, R.7    Robson, M.C.8    Vande Berg, J.9    Reid, P.10
  • 8
    • 0347725622 scopus 로고    scopus 로고
    • Ability of chronic wound fluids to degrade peptide growth factors is associated with increased levels of elastase activity and diminished levels of proteinase inhibitors
    • Yager D.R., Chen S.M., Ward S.I., Oluyinka O., Olytoye M.D., Diegelmann R.F., Cohen I.K. Ability of chronic wound fluids to degrade peptide growth factors is associated with increased levels of elastase activity and diminished levels of proteinase inhibitors. Wound Rep. Reg. 5:1997;23-32.
    • (1997) Wound Rep. Reg. , vol.5 , pp. 23-32
    • Yager, D.R.1    Chen, S.M.2    Ward, S.I.3    Oluyinka, O.4    Olytoye, M.D.5    Diegelmann, R.F.6    Cohen, I.K.7
  • 9
    • 0023546641 scopus 로고
    • Prevention of tissue damage: Inhibition of myeloperoxidase mediated inactivation of α 1-proteianse inhibitor by N-acetyl cysteine, glutathione and methionine
    • Borregaard N., Jensen H.S., Bejerrum O.W. Prevention of tissue damage: inhibition of myeloperoxidase mediated inactivation of α 1-proteianse inhibitor by N-acetyl cysteine, glutathione and methionine. Agents Actions. 22:1987;255-260.
    • (1987) Agents Actions , vol.22 , pp. 255-260
    • Borregaard, N.1    Jensen, H.S.2    Bejerrum, O.W.3
  • 12
    • 0032711332 scopus 로고    scopus 로고
    • Reduction of ultraviolet light-induced oxidative stress by amino acid-based iron-chelators
    • Kitazawa M., Uwasaki K. Reduction of ultraviolet light-induced oxidative stress by amino acid-based iron-chelators. Biochim. Biophys. Acta. 1473:1999;400-408.
    • (1999) Biochim. Biophys. Acta , vol.1473 , pp. 400-408
    • Kitazawa, M.1    Uwasaki, K.2
  • 14
    • 0034040505 scopus 로고    scopus 로고
    • Review: Peridontal disease mechanisms. Reactive oxygen species: A potential role in the pathogenesis of peridontal diseases
    • Waddington R.J., Moseley R., Embery G. Review: peridontal disease mechanisms. Reactive oxygen species: a potential role in the pathogenesis of peridontal diseases. J. Oral Diseases. 6:2000;138-151.
    • (2000) J. Oral Diseases , vol.6 , pp. 138-151
    • Waddington, R.J.1    Moseley, R.2    Embery, G.3
  • 15
    • 0027202705 scopus 로고
    • Wound fluid from chronic leg ulcers contains elevated levels of metalloproteinases MMP-2 and MMP-9
    • Wysocki A.B., Staiano-Coico L., Grinnell F. Wound fluid from chronic leg ulcers contains elevated levels of metalloproteinases MMP-2 and MMP-9. J. Invest. Dermatol. 101:1993;64-68.
    • (1993) J. Invest. Dermatol. , vol.101 , pp. 64-68
    • Wysocki, A.B.1    Staiano-Coico, L.2    Grinnell, F.3
  • 16
    • 0002170426 scopus 로고    scopus 로고
    • Molecular analysis of the environment of healing and chronic wounds: Cytokines, proteases and growth factors
    • Schultz G.S., Mast B.A. Molecular analysis of the environment of healing and chronic wounds: cytokines, proteases and growth factors. Wounds. 10:1998;1F-9F.
    • (1998) Wounds , vol.10
    • Schultz, G.S.1    Mast, B.A.2
  • 18
    • 0028973014 scopus 로고
    • α 1-antitrypsin is degraded and non-functional in chronic wounds but intact and functional in acute wounds: The inhibitor protects fibronectin from degradation by chronic wound fluid enzymes
    • Rao C.N., Ladin D.A., Liu Y.Y., Chilukuri K., Hou Z.Z., Woodley D. α 1-antitrypsin is degraded and non-functional in chronic wounds but intact and functional in acute wounds: the inhibitor protects fibronectin from degradation by chronic wound fluid enzymes. J. Invest. Dermatol. 105:1995;572-578.
    • (1995) J. Invest. Dermatol. , vol.105 , pp. 572-578
    • Rao, C.N.1    Ladin, D.A.2    Liu, Y.Y.3    Chilukuri, K.4    Hou, Z.Z.5    Woodley, D.6
  • 19
    • 0029938994 scopus 로고    scopus 로고
    • Fibronectin degradation in chronic wounds depends on the relative levels of elastase, α1-proteinase inhibitor, and α2-macroglobulin
    • Grinnell F., Zhu M. Fibronectin degradation in chronic wounds depends on the relative levels of elastase, α1-proteinase inhibitor, and α2-macroglobulin. J. Invest. Dermatol. 106:1996;335-341.
    • (1996) J. Invest. Dermatol. , vol.106 , pp. 335-341
    • Grinnell, F.1    Zhu, M.2
  • 20
    • 0001413484 scopus 로고    scopus 로고
    • Interactions of cytokines, growth factors and proteases in acute and chronic wounds
    • Mast B.A., Schultz G.S. Interactions of cytokines, growth factors and proteases in acute and chronic wounds. Wound Rep. Reg. 4:1996;411-420.
    • (1996) Wound Rep. Reg. , vol.4 , pp. 411-420
    • Mast, B.A.1    Schultz, G.S.2
  • 21
    • 0029823105 scopus 로고    scopus 로고
    • Wound fluids from human pressure ulcers contain elevated matrix metalloproteinase levels and activity compared to surgical wound fluids
    • Yager D.R., Zhang L.Y., Liang H.X., Diegelmann R.F., Cohen I.K. Wound fluids from human pressure ulcers contain elevated matrix metalloproteinase levels and activity compared to surgical wound fluids. J. Invest. Dermatol. 107:1996;743-748.
    • (1996) J. Invest. Dermatol. , vol.107 , pp. 743-748
    • Yager, D.R.1    Zhang, L.Y.2    Liang, H.X.3    Diegelmann, R.F.4    Cohen, I.K.5
  • 23
    • 0026056106 scopus 로고
    • Human neutrophil elastase releases a ligand-binding fragment from the 75-kDa tumor necrosis factor (TNF) receptor. Comparison with the proteolytic activity responsible for shedding of TNF receptors from stimulated neutrophils
    • Porteu F., Brockhus M., Wallach D., Engelmann H., Nathan C.F. Human neutrophil elastase releases a ligand-binding fragment from the 75-kDa tumor necrosis factor (TNF) receptor. Comparison with the proteolytic activity responsible for shedding of TNF receptors from stimulated neutrophils. J. Biol. Chem. 266:1991;18846-18853.
    • (1991) J. Biol. Chem. , vol.266 , pp. 18846-18853
    • Porteu, F.1    Brockhus, M.2    Wallach, D.3    Engelmann, H.4    Nathan, C.F.5
  • 24
    • 0029067051 scopus 로고
    • Cleavage of lymphocyte surface antigens CD2, CD4, and CD8 by polymorphonuclear leukocyte elastase and cathepsin G in patients with cystic fibrosis
    • Doring G., Frank F., Boudier C., Herbert S., Fleischer B., Bellon G. Cleavage of lymphocyte surface antigens CD2, CD4, and CD8 by polymorphonuclear leukocyte elastase and cathepsin G in patients with cystic fibrosis. J. Immunol. 154:1995;4842-4850.
    • (1995) J. Immunol. , vol.154 , pp. 4842-4850
    • Doring, G.1    Frank, F.2    Boudier, C.3    Herbert, S.4    Fleischer, B.5    Bellon, G.6
  • 25
    • 0031916810 scopus 로고    scopus 로고
    • Soluble complement receptor type 1 (CD35) in bronchoalveolar lavage of inflammatory lung diseases
    • Hamacher J., Sadallah S., Schifferli J.A., Villard J., Nicod L.B. Soluble complement receptor type 1 (CD35) in bronchoalveolar lavage of inflammatory lung diseases. Eur. Resp. J. 11:1998;112-119.
    • (1998) Eur. Resp. J. , vol.11 , pp. 112-119
    • Hamacher, J.1    Sadallah, S.2    Schifferli, J.A.3    Villard, J.4    Nicod, L.B.5
  • 28
    • 0030111128 scopus 로고    scopus 로고
    • Collagen-based devices for soft tissue repair
    • Pachence J.M. Collagen-based devices for soft tissue repair. J. Biomed. Mater. Res. 33:1996;35-40.
    • (1996) J. Biomed. Mater. Res. , vol.33 , pp. 35-40
    • Pachence, J.M.1
  • 29
    • 0033649641 scopus 로고    scopus 로고
    • The fate of collagen implants in tissue defects
    • Bailey A.J. The fate of collagen implants in tissue defects. Wound Rep. Reg. 8:2000;5-12.
    • (2000) Wound Rep. Reg. , vol.8 , pp. 5-12
    • Bailey, A.J.1
  • 31
    • 85012405294 scopus 로고
    • Collagen and collagen peptide-induced chemotaxis of human blood monocytes
    • Postlethwaite A.E., Kang A.H. Collagen and collagen peptide-induced chemotaxis of human blood monocytes. J. Exp. Med. 143:1976;1299-1307.
    • (1976) J. Exp. Med. , vol.143 , pp. 1299-1307
    • Postlethwaite, A.E.1    Kang, A.H.2
  • 32
    • 0041436616 scopus 로고
    • Chemotactic attraction of human fibroblasts to types I, II and III collagens and collagen derived peptides
    • Postlethwaite A.E., Seyer J.M., Kang A.H. Chemotactic attraction of human fibroblasts to types I, II and III collagens and collagen derived peptides. Proc. Natl. Acad. Sci. U.S.A. 75:1978;871-875.
    • (1978) Proc. Natl. Acad. Sci. U.S.A. , vol.75 , pp. 871-875
    • Postlethwaite, A.E.1    Seyer, J.M.2    Kang, A.H.3
  • 34
    • 0028034363 scopus 로고
    • Application of angiogenic oligosaccharides of hyaluronan increases blood vessel numbers in rat skin
    • Sattar A., Rooney P., Kumar S., Pye D., West D.C., Scott I., Ledger P. Application of angiogenic oligosaccharides of hyaluronan increases blood vessel numbers in rat skin. J. Invest. Dermatol. 103:1994;576-579.
    • (1994) J. Invest. Dermatol. , vol.103 , pp. 576-579
    • Sattar, A.1    Rooney, P.2    Kumar, S.3    Pye, D.4    West, D.C.5    Scott, I.6    Ledger, P.7
  • 36
    • 0025359279 scopus 로고
    • PDGF and FGF stimulate wound healing in the genetically diabetic mouse
    • Greenhalgh D.G., Sprugel K.H., Murray M.J., Ross R. PDGF and FGF stimulate wound healing in the genetically diabetic mouse. Am. J. Pathol. 136:1990;1235-1246.
    • (1990) Am. J. Pathol. , vol.136 , pp. 1235-1246
    • Greenhalgh, D.G.1    Sprugel, K.H.2    Murray, M.J.3    Ross, R.4
  • 37
    • 0028334260 scopus 로고
    • PDGF and TGF-α act synergistically to improve wound healing in the genetically diabetic mouse
    • Brown D.L., Breeden M.P., Greenhalgh D.G. PDGF and TGF-α act synergistically to improve wound healing in the genetically diabetic mouse. J. Surg. Res. 56:1994;562-570.
    • (1994) J. Surg. Res. , vol.56 , pp. 562-570
    • Brown, D.L.1    Breeden, M.P.2    Greenhalgh, D.G.3
  • 38
    • 0029091170 scopus 로고
    • Platelet-derived growth factor levels in wounds of diabetic rats
    • Doxey D.L., Ng M.C., Dill R.E., Iacopino A.M. Platelet-derived growth factor levels in wounds of diabetic rats. Life Sci. 57:1995;1111-1123.
    • (1995) Life Sci. , vol.57 , pp. 1111-1123
    • Doxey, D.L.1    Ng, M.C.2    Dill, R.E.3    Iacopino, A.M.4
  • 39
    • 0030059185 scopus 로고    scopus 로고
    • Transforming growth factor-β and insulin-like growth factor-I in relation to diabetes-induced impairment of wound healing
    • Bitar M.S., Labbad Z.N. Transforming growth factor-β and insulin-like growth factor-I in relation to diabetes-induced impairment of wound healing. J. Surg. Res. 6:1996;113-119.
    • (1996) J. Surg. Res. , vol.6 , pp. 113-119
    • Bitar, M.S.1    Labbad, Z.N.2
  • 40
    • 0030849224 scopus 로고    scopus 로고
    • Reduced expression of PDGF and PDGF receptors during impaired wound healing
    • Beer H.D., Longaker M.T., Werner S. Reduced expression of PDGF and PDGF receptors during impaired wound healing. J. Invest. Dermatol. 109:1997;132-138.
    • (1997) J. Invest. Dermatol. , vol.109 , pp. 132-138
    • Beer, H.D.1    Longaker, M.T.2    Werner, S.3
  • 41
    • 0030950092 scopus 로고    scopus 로고
    • Apoptosis down-regulates inflammation under the advancing epithelial wound edge: Delayed patterns in diabetes and improvement with topical growth factors
    • Brown D.L., Kao W.W., Greenhalgh D.G. Apoptosis down-regulates inflammation under the advancing epithelial wound edge: delayed patterns in diabetes and improvement with topical growth factors. Surgery. 121:1997;372-380.
    • (1997) Surgery , vol.121 , pp. 372-380
    • Brown, D.L.1    Kao, W.W.2    Greenhalgh, D.G.3
  • 42
    • 0028009677 scopus 로고
    • Acidic fibroblast growth factor: Evaluation of topical formulations in a diabetic mouse wound healing model
    • Matuszewska B., Keogan M., Fisher D.M., Soper K.A., Hoe C.M., Huber A.C., Bondi J.V. Acidic fibroblast growth factor: evaluation of topical formulations in a diabetic mouse wound healing model. Pharm. Res. 11:1994;65-71.
    • (1994) Pharm. Res. , vol.11 , pp. 65-71
    • Matuszewska, B.1    Keogan, M.2    Fisher, D.M.3    Soper, K.A.4    Hoe, C.M.5    Huber, A.C.6    Bondi, J.V.7
  • 43
    • 1542425373 scopus 로고    scopus 로고
    • Effect of basic fibroblast growth factor on wound healing in healing-impaired animal models
    • Okumura M., Okuda T., Nakamura T., Yajima M. Effect of basic fibroblast growth factor on wound healing in healing-impaired animal models. Arzneimittel-Forschung. 46:1996;547-551.
    • (1996) Arzneimittel-Forschung. , vol.46 , pp. 547-551
    • Okumura, M.1    Okuda, T.2    Nakamura, T.3    Yajima, M.4
  • 44
    • 0025079682 scopus 로고
    • EGF increases short-term type I collagen accumulation during wound healing in diabetic rats
    • Hennessey P.J., Black C.T., Andrassy R.J. EGF increases short-term type I collagen accumulation during wound healing in diabetic rats. J. Pediatr. Surg. 25:1990;893-897.
    • (1990) J. Pediatr. Surg. , vol.25 , pp. 893-897
    • Hennessey, P.J.1    Black, C.T.2    Andrassy, R.J.3
  • 46
    • 0028004471 scopus 로고
    • Induction of keratinocyte growth factor expression is reduced and delayed during wound healing in the genetically diabetic mouse
    • Werner S., Breeden M., Hubner G., Greenhalgh D.G., Longaker M.T. Induction of keratinocyte growth factor expression is reduced and delayed during wound healing in the genetically diabetic mouse. J. Invest. Dermatol. 103:1994;469-473.
    • (1994) J. Invest. Dermatol. , vol.103 , pp. 469-473
    • Werner, S.1    Breeden, M.2    Hubner, G.3    Greenhalgh, D.G.4    Longaker, M.T.5
  • 47
    • 0021445495 scopus 로고
    • Neutrophil and monocyte behaviour in three-dimensional collagen matrices
    • A.F. Brown, Neutrophil and monocyte behaviour in three-dimensional collagen matrices, Scan Electron. Microsc. II (1984) 747-754.
    • (1984) Scan Electron. Microsc. , vol.2 , pp. 747-754
    • Brown, A.F.1
  • 48
    • 0031042553 scopus 로고    scopus 로고
    • Neutrophil motility in extracellular matrix gels: Mesh size and adhesion affect speed of migration
    • Kuntz R.M., Saltzman W.M. Neutrophil motility in extracellular matrix gels: mesh size and adhesion affect speed of migration. Biophys. J. 72:1997;1472-1480.
    • (1997) Biophys. J. , vol.72 , pp. 1472-1480
    • Kuntz, R.M.1    Saltzman, W.M.2
  • 49
    • 0025821362 scopus 로고
    • Recruitment of peripheral mononuclear cells by mammalian collagenase digests of type I collagen
    • Malone J.D., Richards M., Jeffrey J.J. Recruitment of peripheral mononuclear cells by mammalian collagenase digests of type I collagen. Matrix. 11:1991;289-295.
    • (1991) Matrix , vol.11 , pp. 289-295
    • Malone, J.D.1    Richards, M.2    Jeffrey, J.J.3
  • 50
    • 0022655977 scopus 로고
    • Chemotactic activity of collagen-like polypeptides for human peripheral blood neutrophils
    • Laskin D.L., Kimura T., Sakakibara S., Riley D.J., Berg R.A. Chemotactic activity of collagen-like polypeptides for human peripheral blood neutrophils. J. Leuk. Biol. 39:1986;255-266.
    • (1986) J. Leuk. Biol. , vol.39 , pp. 255-266
    • Laskin, D.L.1    Kimura, T.2    Sakakibara, S.3    Riley, D.J.4    Berg, R.A.5
  • 51
    • 0028127621 scopus 로고
    • Activation of alveolar macrophages by native and synthetic collagen-like polypeptides
    • Laskin D.L., Soltys R.A., Berg R.A., Riley D.J. Activation of alveolar macrophages by native and synthetic collagen-like polypeptides. Am. J. Resp. Cell. Mol. Biol. 10:1994;58-64.
    • (1994) Am. J. Resp. Cell. Mol. Biol. , vol.10 , pp. 58-64
    • Laskin, D.L.1    Soltys, R.A.2    Berg, R.A.3    Riley, D.J.4
  • 53
    • 0021923934 scopus 로고
    • Collagenolytic cleavage products of collagen type I as chemoattractants for human dermal fibroblasts
    • Albini A., Adelmann-Grill B.C. Collagenolytic cleavage products of collagen type I as chemoattractants for human dermal fibroblasts. Eur. J. Cell. Biol. 36:1985;104-107.
    • (1985) Eur. J. Cell. Biol. , vol.36 , pp. 104-107
    • Albini, A.1    Adelmann-Grill, B.C.2
  • 54
    • 0024436074 scopus 로고
    • Synovial fluids from infected joints contain active metalloproteinases and no inhibitory activity
    • Cawston T.E., Weaver L., Coughlan R.J., Kyle M.V., Hazleman B.L. Synovial fluids from infected joints contain active metalloproteinases and no inhibitory activity. Br. J. Rheumatol. 28:1989;386-392.
    • (1989) Br. J. Rheumatol. , vol.28 , pp. 386-392
    • Cawston, T.E.1    Weaver, L.2    Coughlan, R.J.3    Kyle, M.V.4    Hazleman, B.L.5
  • 55
    • 0026605281 scopus 로고
    • Degradation of fibronectin and vitronectin in chronic wound fluid: Analysis by cell blotting, immunoblotting, and cell adhesion assays
    • Grinnell F., Ho C.H., Wysocki A. Degradation of fibronectin and vitronectin in chronic wound fluid: analysis by cell blotting, immunoblotting, and cell adhesion assays. J. Invest. Dermatol. 98:1992;410-416.
    • (1992) J. Invest. Dermatol. , vol.98 , pp. 410-416
    • Grinnell, F.1    Ho, C.H.2    Wysocki, A.3
  • 56
    • 0028981374 scopus 로고
    • Tissue inhibitor of metalloproteinases-1 is decreased and activated gelatinases are increased in chronic wounds
    • Bullen E.C., Longaker M.T., Updike D.L., Benton R., Ladin D., Hou Z., Howard E.W. Tissue inhibitor of metalloproteinases-1 is decreased and activated gelatinases are increased in chronic wounds. J. Invest. Dermatol. 104:1995;236-240.
    • (1995) J. Invest. Dermatol. , vol.104 , pp. 236-240
    • Bullen, E.C.1    Longaker, M.T.2    Updike, D.L.3    Benton, R.4    Ladin, D.5    Hou, Z.6    Howard, E.W.7
  • 59
    • 0031784503 scopus 로고    scopus 로고
    • Patterns of matrix metalloproteinase and TIMP expression in chronic ulcers
    • Saarialho-Kere U.K. Patterns of matrix metalloproteinase and TIMP expression in chronic ulcers. Arch. Dermatol. Res. 290:1998;S47-54.
    • (1998) Arch. Dermatol. Res. , vol.290
    • Saarialho-Kere, U.K.1
  • 60
    • 0033079612 scopus 로고    scopus 로고
    • MMP-8 is the predominant collagenase in healing wounds and non-healing ulcers
    • Nwomeh B.C., Liang H.X., Cohen I.K., Yager D.R. MMP-8 is the predominant collagenase in healing wounds and non-healing ulcers. J. Surg. Res. 81:1999;189-195.
    • (1999) J. Surg. Res. , vol.81 , pp. 189-195
    • Nwomeh, B.C.1    Liang, H.X.2    Cohen, I.K.3    Yager, D.R.4
  • 63
    • 0027286585 scopus 로고
    • Tissue and urokinase plasminogen activators in the environs of venous and ischaemic leg ulcers
    • Stacey M.C., Burnand K.G., Mahmoud-Alexandroni M., Gaffney P.J., Bhogal B.S. Tissue and urokinase plasminogen activators in the environs of venous and ischaemic leg ulcers. Br. J. Surg. 80:1993;596-599.
    • (1993) Br. J. Surg. , vol.80 , pp. 596-599
    • Stacey, M.C.1    Burnand, K.G.2    Mahmoud-Alexandroni, M.3    Gaffney, P.J.4    Bhogal, B.S.5
  • 64
    • 84989023323 scopus 로고
    • Involvement of proteolytic enzymes plasminogen activators and matrix metalloproteinases in the pathophysiology of pressure ulcers
    • Rogers A.A., Burnett S., Moore J.C., Shakespeare P.G., Chen W.Y.J. Involvement of proteolytic enzymes plasminogen activators and matrix metalloproteinases in the pathophysiology of pressure ulcers. Wound Rep. Reg. 3:1995;273-283.
    • (1995) Wound Rep. Reg. , vol.3 , pp. 273-283
    • Rogers, A.A.1    Burnett, S.2    Moore, J.C.3    Shakespeare, P.G.4    Chen, W.Y.J.5
  • 65
    • 0030880539 scopus 로고    scopus 로고
    • Up-regulation of elastase in acute wounds of healthy aged humans and chronic venous leg ulcers are associated with matrix degradation
    • Herrick S., Ashcroft G., Ireland G., Horan M., McCollum C., Ferguson M. Up-regulation of elastase in acute wounds of healthy aged humans and chronic venous leg ulcers are associated with matrix degradation. Lab. Invest. 77:1997;281-288.
    • (1997) Lab. Invest. , vol.77 , pp. 281-288
    • Herrick, S.1    Ashcroft, G.2    Ireland, G.3    Horan, M.4    McCollum, C.5    Ferguson, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.