Design, synthesis and biochemical evaluation of AC ring mimics as novel inhibitors of the enzyme estrone sulfatase (ES)

Journal of Steroid Biochemistry and Molecular Biology

Volumn 82, Issue 4-5, 2002, Pages 425-435

  Ahmed, Sabbir ^a   James, Karen ^b   Owen, Caroline P ^a  

^a KINGSTON UNIVERSITY   (United Kingdom)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

COUMATE; EMATE; Estrone sulfatase

Indexed keywords

4 METHYLCOUMARIN 7 O SULFAMATE; BIPHENYL DERIVATIVE; ENZYME INHIBITOR; ESTRONE 3 O SULFAMATE; ESTRONE SULFATASE INHIBITOR; SULFONAMIDE; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; MOLECULAR MIMICRY; MOLECULAR MODEL;

COUMARINS; DRUG DESIGN; ENZYME INHIBITORS; ESTRONE; INHIBITORY CONCENTRATION 50; KINETICS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR MIMICRY; STRUCTURE-ACTIVITY RELATIONSHIP; SULFATASES; SULFONAMIDES;

EID: 0036877430     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(02)00228-5     Document Type: Article

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