Synthesis and biochemical evaluation of novel and potent inhibitors of the enzyme oestrone sulphatase (ES)

Journal of Steroid Biochemistry and Molecular Biology

Volumn 80, Issue 4-5, 2002, Pages 419-427

  Ahmed, Sabbir ^a   James, Karen ^a   Owen, Caroline P ^a   Patel, Chirag K ^a  

^a KINGSTON UNIVERSITY   (United Kingdom)

Author keywords

Biochemical evaluation; Inhibitors; Novel; Oestrone; Sulphatase; Synthesis

Indexed keywords

4 HEPTANOYLPHENYLSULFAMATE; 4 METHYLCOUMARIN 7 O SULFAMATE; 4 NONANOYLPHENYLSULFAMATE; 4 OCTANOYLPHENYLSULFAMATE; ENZYME INHIBITOR; ESTRONE 3 SULFAMATE; ESTRONE SULFATE; KETONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOASSAY; BIOCHEMISTRY; DRUG INHIBITION; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; HYDROLYSIS; MOLECULAR MODEL; STRUCTURE ACTIVITY RELATION;

COUMARINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; ESTRONE; HUMANS; HYDROLYSIS; INHIBITORY CONCENTRATION 50; KINETICS; MICROSOMES; MODELS, CHEMICAL; PLACENTA; SPECTROPHOTOMETRY, INFRARED; SULFATASES; SULFONAMIDES; TIME FACTORS;

EID: 0036225438     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(02)00037-7     Document Type: Article

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