Determination and use of a transition state for the enzyme estrone sulfatase (ES) from a proposed reaction mechanism

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 23, 2001, Pages 3001-3005

  Ahmed, Sabbir ^a   James, Karen ^a   Owen, Caroline P ^a   Patel, Chirag K ^a   Patel, Mijal B ^a  

^a KINGSTON UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME; ENZYME INHIBITOR; ESTRONE SULFATASE; STEROID; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL ANALYSIS; CHEMICAL REACTION; CONFORMATIONAL TRANSITION; DRUG ACTIVITY; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME STRUCTURE; MOLECULAR MODEL;

CATALYTIC DOMAIN; COUMARINS; ENZYME INHIBITORS; ESTRONE; INHIBITORY CONCENTRATION 50; MODELS, MOLECULAR; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; SULFATASES; SULFONAMIDES;

EID: 0035802997     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00607-2     Document Type: Article

References (13)