Transplantation of a new composite of neural cells and marrow stromal cells into rat brain after stroke

Neuroscience Research Communications

Volumn 31, Issue 3, 2002, Pages 155-163

  Li, Yi ^a   Yang, Xiaoyi ^b   Chen, Jieli ^a   Wang, Lei ^a   Wang, Ying ^a   Zhang, Chunling ^a   Chen, Xiaoguang ^a   Katakowski, Mark ^a,c   Mikkelsen, Tom ^b   Lu, Mei ^b   Chopp, Michael ^a,c  

^a HENRY FORD HOSPITAL   (United States)

^b HENRY FORD HEALTH SCIENCES CENTER   (United States)

^c OAKLAND UNIVERSITY   (United States)

Author keywords

A new cell aggregate model; Bone marrow stromal cells; Neurosphere; Rat; Stroke

Indexed keywords

BIOMATERIAL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; BRAIN CELL; BRAIN ISCHEMIA; CELL ASSAY; CELL CULTURE; CELL DEATH; CELL TRANSPLANTATION; CONTROLLED STUDY; FEMALE; FETUS; FETUS CELL; IMPLANTATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEURAL CREST CELL; NONHUMAN; RAT; STROKE;

EID: 0036872134     PISSN: 08936609     EISSN: None     Source Type: Journal    
DOI: 10.1002/nrc.10048     Document Type: Article

References (32)

1. Snyder EY, Deitcher DL, Walsh C, Arnold-Aldea S, Hartwieg EA, Cepko CL. Multipotent neural cell lines can engraft and participate in development of mouse cerebellum. Cell 1992;68(1):33-51.
2. Gage FH, Ray J, Fisher LJ. Isolation, characterization, and use of stem cells from the CNS. Annu Rev Neurosci 1995;18:159-192.
3. Whittemore SR, Snyder EY. Physiological relevance and functional potential of central nervous system-derived cell lines. Mol Neurobiol 1996;12(1):13-38.
4. Borlongan CV, Stahl CE, Cameron DF, Saporta S, Freeman TB, Cahill DW, et al. CNS immunological modulation of neural graft rejection and survival. Neurol Res 1996;18(4):297-304.
5. Borlongan CV, Tajima Y, Trojanowski JQ, Lee VM, Sanberg PR. Cerebral ischemia and CNS transplantation: differential effects of grafted fetal rat striatal cells and human neurons derived from a clonal cell line. Neuroreport 1998;9(16):3703-3709.
6. Bjorklund A, Lindvall O. Cell replacement therapies for central nervous system disorders. Nat Neurosci 2000;3(6):537-544.
7. Dunnett SB, Bjorklund A, Lindvall O. Cell therapy in Parkinson's disease - stop or go? Nat Rev Neurosci 2001;2(5):365-369.
8. Gage FH. Neurogenesis in the adult brain. J Neurosci 2002;22(3):612-613.
9. Borlongan CV, Tajima Y, Trojanowski JQ, Lee VM, Sanberg PR. Transplantation of cryopreserved human embryonal carcinoma-derived neurons (NT2N cells) promotes functional recovery in ischemic rats. Exp Neurol 1998;149(2):310-321.
10. Grabowski M, Brundin P, Johansson BB. Fetal neocortical grafts implanted in adult hypertensive rats with cortical infarcts following a middle cerebral artery occlusion: ingrowth of afferent fibers from the host brain. Exp Neurol 1992; 116(2):105-121.
11. Grabowski M, Brundin P, Johansson BB. Functional integration of cortical grafts placed in brain infarcts of rats. Ann Neurol 1993;34(3):362-368.
12. Goto S, Yamada K, Yoshikawa M, Okamura A, Ushio Y. GABA receptor agonist promotes reformation of the striatonigral pathway by transplant derived from fetal striatal primordia in the lesioned striatum. Exp Neurol 1997;147(2):503-509.
13. Eglitis MA, Dawson D, Park KW, Mouradian MM. Targeting of marrow-derived astrocytes to the ischemic brain. Neuroreport 1999;10(6):1289-1292.
14. Li Y, Chopp M, Chen J, Wang L, Gautam SC, Xu YX, et al. Intrastriatal transplantation of bone marrow nonhematopoietic cells improves functional recovery after stroke in adult mice. J Cereb Blood Flow Metab 2000;20(9):1311-1319.
15. Chen J, Li Y, Wang L, Lu M, Zhang X, Chopp M. Therapeutic benefit of intracerebral transplantation of bone marrow stromal cells after cerebral ischemia in rats. J Neurol Sci 2001;189(1-2):49-57.
16. Chen J, Sanberg PR, Li Y, Wang L, Lu M, Willing AE, et al. Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats. Stroke 2001;32(11):2682-2688.
17. Chen J, Li Y, Wang L, Zhang Z, Lu D, Lu M, et al. Therapeutic benefit of intravenous administration of bone marrow stromal cells after cerebral ischemia in rats. Stroke 2001;32(4):1005-1011.
18. Schallert T, Hernandez TD, Barth TM. Recovery of function after brain damage: severe and chronic disruption by diazepam. Brain Res 1986;379(1):104-111.
19. Hernandez TD, Schallert T. Seizures and recovery from experimental brain damage. Exp Neurol 1988;102(3):318-324.
20. Morris DC, Davies K, Zhang Z, Chopp M. Measurement of cerebral microvessel diameters after embolic stroke in rat using quantitative laser scanning confocal microscopy. Brain Res 2000;876(1-2):31-36.
21. Zhang Z, Davies K, Prostak J, Fenstermacher J, Chopp M. Quantitation of microvascular plasma perfusion and neuronal microtubule-associated protein in ischemic mouse brain by laser-scanning confocal microscopy. J Cereb Blood Flow Metab 1999;19(1):68-78.
22. Zhang ZG, Chopp M, Goussev A, Lu D, Morris D, Tsang W, et al. Cerebral microvascular obstruction by fibrin is associated with upregulation of PAI-1 acutely after onset of focal embolic ischemia in rats. J Neurosci 1999;19(24):10898-10907.
23. Paxinos G, Watson C. The rat brain in stereotaxic coordinates. 2nd ed. Sydney; Orlando: Academic Press; 1986.
24. Tamada Y, Fukiage C, Boyle DL, Azuma M, Shearer TR. Involvement of cysteine proteases in bFGF-induced angiogenesis in guinea pig and rat cornea. J Ocul Pharmacol Ther 2000;16(3):271-283.
25. Cramer SC, Nelles G, Benson RR, Kaplan JD, Parker RA, Kwong KK, et al. A functional MRI study of subjects recovered from hemiparetic stroke. Stroke 1997;28(12):2518-2527.
26. Weiller C, Ramsay SC, Wise RJ, Friston KJ, Frackowiak RS. Individual patterns of functional reorganization in the human cerebral cortex after capsular infarction. Ann Neurol 1993;33(2):181-189.
27. Plate KH. Mechanisms of angiogenesis in the brain. J Neuropathol Exp Neurol 1999;58(4):313-320.
28. Leventhal C, Rafii S, Rafii D, Shahar A, Goldman SA. Endothelial trophic support of neuronal production and recruitment from the adult mammalian subependyma. Mol Cell Neurosci 1999;13(6):450-464.
29. Palmer TD, Willhoite AR, Gage FH. Vascular niche for adult hippocampal neurogenesis. J Comp Neurol 2000;425(4):479-494.
30. Cramer SC, Chopp M. Recovery recapitulates ontogeny. Trends Neurosci 2000;23(6):265-271.
31. Zhang ZG, Zhang L, Jiang Q, Zhang R, Davies K, Powers C, et al. VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain. J Clin Invest 2000;106(7):829-838.
32. Chen XG, Katakowski M, Li Y, Lu D, Wang L, Zhang L, et al. Human bone marrow stromal cell cultures conditioned by traumatic brain tissue extracts: Growth factor production. Journal of Neuroscience Research 2002;69:687-691.