Intrastriatal transplantation of bone marrow nonhematopoietic cells improves functional recovery after stroke in adult mice

Journal of Cerebral Blood Flow and Metabolism

Volumn 20, Issue 9, 2000, Pages 1311-1319

  Li, Yi ^a   Chopp, Michael ^a,b   Chen, Jieli ^a   Wang, Lei ^a   Gautam, Subhash C ^c   Xu, Yong Xian ^b   Zhang, Zhenggang ^a  

^a HENRY FORD HOSPITAL   (United States)

^b OAKLAND UNIVERSITY   (United States)

^c HENRY FORD HEALTH SCIENCES CENTER   (United States)

Author keywords

Bone marrow cells; Mice; Stroke; Transplantation

Indexed keywords

BROXURIDINE; GLIAL FIBRILLARY ACIDIC PROTEIN;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL MODEL; ARTICLE; ASTROCYTE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CELL FUNCTION; CONTROLLED STUDY; CONVALESCENCE; CORPUS STRIATUM; HISTOPATHOLOGY; MIDDLE CEREBRAL ARTERY OCCLUSION; MOTOR ACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; REFLEX; STROKE;

EID: 0033844402     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-200009000-00006     Document Type: Article

References (62)

1. Striatal grafts in infarct striatopallidum increase GABA release, reorganize GABAA receptor and improve water-maze learning in the rat
2. Engraftment of migration of human bone marrow stromal cells implanted in the brains of albino rats-similarities to astrocyte grafts
3. Trophism, transplantation, and animal models of Parkinson's disease
4. Expression of BMP-2 by rat bone marrow stromal cells in culture
5. Transplanted nerve cells survive and are functional for many years
6. The blood and the lymphoid organs
7. Neural transplantation as an experimental treatment modality for cerebral ischemia
8. Asymmetrical motor behavior in rats with unilateral striatal excitotoxic lesions as revealed by the elevated body swing test
9. Cerebral ischemia and CNS transplantation: Differential effects of grafted fetal rat striatal cells and human neurons derived from a clonal cell line
10. Mesenchymal stem cells in osteobiology and applied bone regeneration
11. Motor and cognitive deficits in apolipoprotein E-deficient mice after closed head injury
12. Rapid expansion of recycling stem cells in cultures of plastic-adherent cells from human bone marrow
13. Long-term outcome of unilaterally transplanted parkinsonian patients, I. Clinical approach
14. Photochemical stroke model: Flunarizine prevents sensorimotor deficits after neocortical infarcts in rats
15. Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. II. Analysis of positive and negative regulators produced by stromal cells within the adherent layer
16. Targeting of marrow-derived astrocytes to the ischemic brain
17. Hematopoietic cells differentiate into both microglia and macroglia in the brains of adult mice
18. Transplantation of fetal mesencephalic tissue in Parkinson's disease
19. Cell therapy
20. Mammalian neural stem cells
21. Isolation, characterization, and use of stem cells from the CNS
22. Behavioral deficits following experimental subarachnoid hemorrhage in the rat
23. GABA receptor agonist promotes reformation of the striatonigral pathway by transplant derived from fetal striatal primordia in the lesioned striatum
24. The rotarod test: An evaluation of its effectiveness in assessing motor deficits following traumatic brain injury
25. Subcortical neglect
26. Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta
27. Regulation of dopamine production by genetically modified primary fibroblasts
28. Treatment of genetic defects in hematopoietic cell function by gene transfer
29. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains
30. Neuropathologic evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease
31. Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): Implications for therapeutic use
32. Neuronal differentiation of precursors in the neocortical ventricular zone is triggered by BMP
33. Intact, injured, necrotic and apoptotic cells after focal cerebral ischemia in the rat
34. Temporal profile of nestin expression after focal cerebral ischemia in adult rat
35. Regression of parkinsonian fetal ventral mesencephalon grafts upon withdrawal of cyclosporine A immunosuppression
36. Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells
37. Sensorimotor and cognitive consequences of middle cerebral artery occlusion in rats
38. Expression of human bone morphogenic protein 7 in primary rabbit periosteal cells: Potential utility in gene therapy for osteochondral repair
39. The hematopoietic cytokine colony stimulating factor 1 is also a growth factor in the CNS: (II). Microencapsulated CSF-1 and LM-10 cells as delivery systems
40. Striatal grafts in the ischemic striatum improve pallidal GABA release and passive avoidance
41. Early cytopathic features in rat ischemia model and reconstruction by neural graft
42. Marrow stromal cells as a source of progenitor cells for nonhematopoietic tissues in transgenic mice with a phenotype of osteogenesis imperfecta
43. Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice
44. Plastic adherent stromal cells from the bone marrow of commonly used strains of inbred mice: Variations in yield, growth, and differentiation
45. Fine structure of medulloepithelioma
46. Marrow stromal cells as stem cells for nonhematopoietic tissues
47. Marrow stromal cells as stem cells for continual renewal of nonhematopoietic tissues and as potential vectors for gene therapy
48. Phenotypic and functional changes induced at the clonal level in hematopoietic stem cells after 5-fluorouracil treatment
49. Induction of bone formation using a recombinant adenoviral vector carrying the human BMP-2 gene in a rabbit spinal fusion model
50. Use-dependent structural events in recovery of function
51. Long-term effect of HU-211, a novel non-competitive NMDA antagonist, on motor and memory functions after closed head injury in the rats
52. Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex
53. Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with Parkinson's disease
54. A semiautomated method for measuring brain infarct volume
55. The trophic cocktail made by adrenal chromaffin cells
56. Growth factors in Parkinson's disease
57. Can old cells learn new tricks?
58. Phenotypic correction of fanconi anemia in human hematopoietic cells with a recombinant adeno-associated virus vector
59. Reversible middle cerebral artery occlusion without craniectomy in rats
60. A mouse model of embolic focal cerebral ischemia