Iodinated contrast media induce neutrophil apoptosis through a mitochondrial and caspase mediated pathway

British Journal of Radiology

Volumn 75, Issue 899, 2002, Pages 861-873

  Fanning, N F ^a   Manning, B J ^a   Buckley, J ^a   Redmond, H P ^a  

^a University College Cork and INFANT Centre   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; CASPASE; CASPASE INHIBITOR; CONTRAST MEDIUM; DIATRIZOATE; IODINE; IOHEXOL; IOTROLAN; IOXAGLIC ACID; LIPOCORTIN 5; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; SYNAPTOPHYSIN;

ADULT; APOPTOSIS; ARTICLE; CELL STIMULATION; CELL SURVIVAL; CHEMICAL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOMETRY; DRUG INHIBITION; ENDOTHELIUM CELL; ENZYME ACTIVITY; HEART DEPOLARIZATION; HEART MUSCLE CELL; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IMMUNE RESPONSE; IMMUNITY; IMMUNOCOMPETENT CELL; IN VITRO STUDY; INFECTION; INJURY; INTRACELLULAR TRANSPORT; KIDNEY CELL; MITOCHONDRION; NEUTROPHIL; NORMAL HUMAN; SIGNAL TRANSDUCTION; VOLUNTEER; WESTERN BLOTTING;

EID: 0036860425     PISSN: 00071285     EISSN: None     Source Type: Journal    
DOI: 10.1259/bjr.75.899.750861     Document Type: Article

References (50)

1. Hizoh I, Strater J, Schick CS, Kubler W, Haller C. Radioconstrast-induced DNA fragmentation of renal tubular cells in vitro: Role of hypertonicity. Nephrol Dial Transplant 1998;13:911-8.
2. Zhang J, Duarte CG, Ellis S. Contrast medium- and mannitol-induced apoptosis in heart and kidney of SHR rats. Toxicol Pathol 1999;27:427-35.
3. Beeri R, Symon Z, Brezis M, Ben-Sasson SA, Baehr PH, Rosen S, et al. Rapid DNA fragmentation from hypoxia along the thick ascending limb of rat kidneys. Kidney Int 1995;47:1806-1810.
4. Zhang H, Holt CM, Malik N, Shepherd L, Morcos SK. Effects of radiographic contrast media on proliferation of human vascular endothelial cells. Br J Radiol 2000;73:1034-41.
5. Heyman SN, Fuchs S, Jaffe R, Shina A, Ellezian L, Brezis M, et al. Renal microcirculation and tissue damage during acute ureteral obstruction in the rat: Effect of saline infusion, indomethacin and radio-constrast. Kidney Int 1997;51:653-63.
6. Savill J. Apoptosis in resolution of inflammation. J Leukoc Biol 1997;61:375-80.
7. Fanning NF, Kell MR, Shorten GD, Kirwan WO, Bouchier-Hayes D, Cotter TG, et al. Circulating granulocyte macrophage colony-stimulating factor in plasma of patients with the systemic inflammatory response syndrome delays neutrophil apoptosis through inhibition of spontaneous reactive oxygen species generation. spontaneous reactive oxygen species generation. Shock 1999;11:167-74.
8. Kusaba N, Kumashiro R, Ogata H, Sata M, Tanikawa K. In vitro study of neutrophil apoptosis in liver cirrhosis. Intern Med 1998;37:11-7.
9. Carmona-Sanchez R, Uscanga L, Bezaury-Rivas P, Robles-Diaz G, Suazo-Barahona J, Vargas-Vorackova F. Potential harmful effect of iodinated intravenous contrast medium on the clinical course of mild acute pancreatitis. Arch Surg 2000;135:1280-4.
10. Orlov SN, Dam TV, Tremblay J, Hamet P. Apoptosis in vascular smooth muscle cells: Role of cell shrinkage. Biochem Biophys Res Commun 1996;221:708-15.
11. Duke RC, Cohen JJ. IL-2 addiction: Withdrawal of growth factor activates a suicide program in dependent T cells. Lymphokine Res 1986;5:289-99.
12. MacGregor RR, Spagnuolo PJ, Lentnek AL. Inhibition of granulocyte adherence by ethanol, prednisone, and aspirin, measured with an assay system. N Engl J Med 1974;291:642-6.
13. Martin SJ, Reutelingsperger CP, McGahon AJ, Rader JA, Van Schie RC, LaFace DM, et al. Early redistribution of plasma membrane phosphatidyl-serine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl. J Exp Med 1995;182:1545-56.
14. Cossarizza A, Baccarani-Contri M, Kalashnikova G, Franceschi C. A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazol-c arbocyanine iodide (JC-1). Biochem Biophys Res Commun 1993;197:40-5.
15. Cossarizza A, Ceccarelli D, Masini A. Functional heterogeneity of an isolated mitochondrial population revealed by cytofluorometric analysis at the single organelle level. Exp Cell Res 1996;222:84-94.
16. Reers M, Smith TW, Chen LB. J-aggregate formation of a carbocyanine as a quatitative fluorescent indicator of membrane potential. Biochemistry 1991;30: 4480-6.
17. Smiley ST, Reers M, Mottola-Harstshorn C, Lin M, Chen A, Smith TW, et al. Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. Proc Natl Acad Sci U S A 1991;88:3671-5.
18. Lee A, Whyte MK, Haslett C. Inhibition of apoptosis and prolongation of neutrophil functional longevity by inflammatory mediators. J Leukoc Biol 1993;54:283-8.
19. Pryde JG, Walker A, Rossi AG, Hannah S, Haslett C. Temperature-dependent arrest of neutrophil apoptosis. Failure of Bax insertion into mitochondria at 15 degrees C prevents the release of cytochrome c. J Biol Chem 2000;275:33574-84.
20. Khwaja A, Tatton L. Caspase-mediated proteolysis and activation of protein kinase Cdelta plays a central role in neutrophil apoptosis. Blood 1999;94:291-301.
21. Schick CS, Haller C. Comparative cytotoxicity of ionic and non-ionic radiocontrast agents on MDCK cell monolayers in vitro. Nephrol Dial Transplant 1999;14:342-7.
22. Bourin M, Jolliet P, Ballereau F. An overview of the clinical pharmacokinetics of X-ray contrast media. Clin Pharmacokinet 1997;32:180-93.
23. Gmelin E, Rinast E, Ollrogge C. Arterial bolus curve after intravenous injection of ionic and nonionic contrast media. In: Taenzer V, Wende S, editors. Recent Developments in Nonionic Contrast Media. New York, NY: Thieme Medical Publishers, Inc.; 1989:67-9.
24. Roobottom CA, Farrow R, Wells IP, Hurlock N. The effects of radiographic contrast media on leucocyte orientation. Br J Radiol 1993;66:778-80.
25. Vitale M, Di Matola T, D'Ascoli F, Salzano S, Bogazzi F, Fenzi G, et al. Iodide excess induces apoptosis in thyroid cells through a p53-independent mechanism involving oxidative stress. Endocrinology 2000;141:598-605.
26. Burikhanov RB, Matsuzaki S. Excess iodine induces apoptosis in the thyroid of goitrogen-pretreated rats in vivo. Thyroid 2000;10:123-9.
27. Alvarez E. Neutropenia in a burned patient being treated topically with providone-iodine foam. Plast Reconstr Surg 1979;63:839-40.
28. Schenck HU, Simak P. Haedicke E. Structure of polyvinylpyrrolidone-iodine (povidone-iodine). J Pharm Sci 1979;68:1505-9.
29. Haller C, Schick CS, Zorn M, Kubler W. Cytotoxicity of radiocontrast agents on polarized renal epithelial cell monolayers. Cardiovasc Res 1997;33:655-65.
30. Wang YX, Chan P, Morcos SK. The effect of radiographic contrast media on human vascular smooth muscle cells. Br J Radiol 1998;71:376-80.
31. Heyman SN, Fuchs S, Jaffe R, Shina A, Ellezian L, Brezis M, et al. Renal microcirculation and tissue damage during acute ureteral obstruction in the rat: Effect of saline infusion, indomethacin and radio-contrast. Kidney Int 1997;51:652-63.
32. Moulding DA, Quayle JA, Hart CA, Edwards SW. Mcl-1 expression in human neutrophils: Regulation by cytokines and correlation with cell survival. Blood 1998;92:2495-502.
33. Hsieh SC, Huang MH, Tsai CY, Tsai YY, Tsai ST, Sun KH, et al. The expression of genes modulating programmed cell death in normal human polymorphonuclear neutrophils. Biochem Biophys Res Commun 1997;233:700-6.
34. Wei S, Liu JH, Epling-Burnette PK, Gamero AM, Ussery D, Pearson EW, et al. Critical role of Lyn kinase in inhibition of neutrophil apoptosis by granulocyte-macrophage colony-stimulating factor. J Immunol 1996;157:5155-62.
35. Frasch SC, Nick JA, Fadok VA, Bratton DL, Worthen GS, Henson PM. p38 mitogen-activated protein kinase-dependent and -independent intracellular signal transduction pathways leading to apoptosis in human neutrophils. J Biol Chem 1998;273:8389-97.
36. Nolan B, Duffy A, Paquin L, De M, Collette H, Graziano CM, et al. Mitogen-activated protein kinases signal inhibition of apoptosis in lipopoly-saccharide-stimulated neutrophils. Surgery 1999;126:406-12.
37. Sanghavi DM, Thelen M, Thornberry NA, Casciola-Rosen L, Rosen A. Caspase-mediated proteolysis during apoptosis: Insights from apoptotic neutrophils. FEBS Lett 1998;422:179-84.
38. Korsmeyer SJ. Regulators of cell death. Trends Genet 1995;11:101-5.
39. Yamashita K, Takahashi A, Kobayashi S, Hirata H, Mesner PW Jr, Kaufmann SH, et al. Caspases mediate tumor necrosis factor-alpha-induced neutrophil apoptosis and downregulation of reactive oxygen production. Blood 1999;93:674-85.
40. Yuan JY, Horvitz HR. The Caenorhabditis elegans genes and ced-3 and ced-4 act cell autonomously to cause programmed cell death. Dev Biol 1990;138:33-41.
41. Stennicke HR, Jurgensmeier JM, Shin H, Deveraux Q, Wolf BB, Yang X, et al. Pro-caspase-3 is a major physiologic target of caspase-8. J Biol Chem 1998;273:27084-90.
42. Kuwana T, Smith JJ, Muzio M, Dixit V, Newmeyer DD, Kornbluth S. Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c. J Biol Chem 1998;273:16589-94.
43. Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES, et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997;91:479-89.
44. Susin SA, Zamzami N, Castedo M, Hirsch T, Marchetti P, Macho A, et al. Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J Exp Med 1996;184:1331-41.
45. Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD. The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis [see comments]. Science 1997;275:1132-6.
46. Zou H, Henzel WJ, Liu X, Lutschg A, Wang X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3 [see comments]. Cell 1997;90:405-13.
47. Bossy-Wetzel E, Newmeyer DD, Green DR. Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization. EMBO J 1998;17:37-49.
48. Goldstein JC, Waterhouse NJ, Juin P, Evan GI, Green DR. The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant. Nat Cell Biol 2000;2:156-62.
49. Liu X, Kim CN, Yang J, Jemmersen R, Wang X, Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c. Cell 1996;86:147-57.
50. Guidolet J, Barbe R, Borsson F, Gateau O, Amiel M, Louisot P. Cardiovascular radiology. Subcellular localization of uro-angiographic contrast by 125I-labeled media. Invest Radiol 1980;15:S215-19.