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Volumn 147, Issue 5, 2002, Pages 689-700

Insulin influences the nitric oxide cyclic nucleotide pathway in cultured human smooth muscle cells from corpus cavernosum by rapidly activating a constitutive nitric oxide synthase

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ARGININE; CALCIUM; CALCIUM IONOPHORE; CELL PROTEIN; CITRULLINE; CYCLIC AMP; CYCLIC GMP; CYCLIC NUCLEOTIDE; FORSKOLIN; GUANYLATE CYCLASE; ILOPROST; INSULIN; IONOMYCIN; MESSENGER RNA; N(G) METHYL DEXTRO ARGININE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHODIESTERASE; RECOMBINANT HUMAN INSULIN; WORTMANNIN;

EID: 0036854506     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1470689     Document Type: Article
Times cited : (14)

References (52)
  • 4
    • 0030637768 scopus 로고    scopus 로고
    • Neurotransmission and the contraction and relaxation of penile erectile tissue
    • Andersson KE & Stief CG. Neurotransmission and the contraction and relaxation of penile erectile tissue. World Journal of Urology 1997 15 14-20.
    • (1997) World Journal of Urology , vol.15 , pp. 14-20
    • Andersson, K.E.1    Stief, C.G.2
  • 7
    • 0033428493 scopus 로고    scopus 로고
    • Physiology and pathophysiology of erection: Consequences for present medical therapy of erectile dysfunction
    • Schultheiss D & Stief CG. Physiology and pathophysiology of erection: consequences for present medical therapy of erectile dysfunction. Andrologia 1999 31 (Suppl 1) 59-64.
    • (1999) Andrologia , vol.31 , Issue.SUPPL. 1 , pp. 59-64
    • Schultheiss, D.1    Stief, C.G.2
  • 10
    • 0025733506 scopus 로고
    • A nitric oxide-like factor mediates nonadrenergic-noncholinergic neurogenic relaxation of penile corpus cavernosum smooth muscle
    • Kim N, Azadzoi KM, Goldstein I & Saenz de Tajeda I. A nitric oxide-like factor mediates nonadrenergic-noncholinergic neurogenic relaxation of penile corpus cavernosum smooth muscle. Journal of Clinical Investigation 1991 88 112-118.
    • (1991) Journal of Clinical Investigation , vol.88 , pp. 112-118
    • Kim, N.1    Azadzoi, K.M.2    Goldstein, I.3    Saenz de Tajeda, I.4
  • 12
    • 0026353632 scopus 로고
    • Nitric oxide as a mediator of the corpus cavernosum in response to noncholinergic, nonadrenergic neurotransmission
    • Raifer J, Aronson WJ, Bush PA, Dorey FJ & Ignarro LJ. Nitric oxide as a mediator of the corpus cavernosum in response to noncholinergic, nonadrenergic neurotransmission. New England Journal of Medicine 1992 326 90-94.
    • (1992) New England Journal of Medicine , vol.326 , pp. 90-94
    • Raifer, J.1    Aronson, W.J.2    Bush, P.A.3    Dorey, F.J.4    Ignarro, L.J.5
  • 13
    • 0029364219 scopus 로고
    • Nitric oxide synthase and vasoactive intestinal polypeptide colocalization in neurons innervating the human penile circulation
    • Ehmke H, Junemann KP, Mayer B & Kummer W. Nitric oxide synthase and vasoactive intestinal polypeptide colocalization in neurons innervating the human penile circulation. International Journal of Impotence Research 1995 7 147-156.
    • (1995) International Journal of Impotence Research , vol.7 , pp. 147-156
    • Ehmke, H.1    Junemann, K.P.2    Mayer, B.3    Kummer, W.4
  • 16
    • 0026630039 scopus 로고
    • Nitric oxide mediates relaxation in rabbit and human corpus cavernosum smooth muscle
    • Knispel HH, Goessl C & Beckmann R. Nitric oxide mediates relaxation in rabbit and human corpus cavernosum smooth muscle. Urological Research 1992 20 253-257.
    • (1992) Urological Research , vol.20 , pp. 253-257
    • Knispel, H.H.1    Goessl, C.2    Beckmann, R.3
  • 17
    • 0028859180 scopus 로고
    • Role of nitric oxide in the physiology of erection
    • Burnett AL. Role of nitric oxide in the physiology of erection. Biology of Reproduction 1995 52 485-489.
    • (1995) Biology of Reproduction , vol.52 , pp. 485-489
    • Burnett, A.L.1
  • 18
    • 0031060411 scopus 로고    scopus 로고
    • Nitric oxide in the penis: Physiology and pathology
    • Burnett AL. Nitric oxide in the penis: physiology and pathology. Journal of Urology 1997 157 320-324.
    • (1997) Journal of Urology , vol.157 , pp. 320-324
    • Burnett, A.L.1
  • 19
    • 0030939228 scopus 로고    scopus 로고
    • Nitric oxide is involved in the inhibitory neurotransmission and endothelium-dependent relaxations of human small penile arteries
    • Simonsen V, Prieto D, Delgado JA, Hernandez M, Resel L, Saenz de Tejade IS et al. Nitric oxide is involved in the inhibitory neurotransmission and endothelium-dependent relaxations of human small penile arteries. Clinical Science 1997 92 269-275.
    • (1997) Clinical Science , vol.92 , pp. 269-275
    • Simonsen, V.1    Prieto, D.2    Delgado, J.A.3    Hernandez, M.4    Resel, L.5    Saenz de Tejade, I.S.6
  • 20
    • 0028824010 scopus 로고
    • The penis as a vascular organ: The importance of corporal smooth muscle tone in the control of erection
    • Christ GJ. The penis as a vascular organ: the importance of corporal smooth muscle tone in the control of erection. Urologic Clinics of North America 1995 22 727-745.
    • (1995) Urologic Clinics of North America , vol.22 , pp. 727-745
    • Christ, G.J.1
  • 21
    • 0002845713 scopus 로고    scopus 로고
    • Molecular biology of erectile function and dysfunction
    • Lue TF & Dahiya R. Molecular biology of erectile function and dysfunction. Molecular Urology 1997 1 55-64.
    • (1997) Molecular Urology , vol.1 , pp. 55-64
    • Lue, T.F.1    Dahiya, R.2
  • 22
    • 0030071844 scopus 로고    scopus 로고
    • The rationale for prostaglandin E1 in erectile failure: A survey of worldwide experience
    • Porst H. The rationale for prostaglandin E1 in erectile failure: a survey of worldwide experience. Journal of Urology 1996 155 802-815.
    • (1996) Journal of Urology , vol.155 , pp. 802-815
    • Porst, H.1
  • 25
    • 0026634314 scopus 로고
    • Regulation of contraction and relaxation in arterial smooth muscle
    • Rembold CM. Regulation of contraction and relaxation in arterial smooth muscle. Hypertension 1992 20 129-137.
    • (1992) Hypertension , vol.20 , pp. 129-137
    • Rembold, C.M.1
  • 26
  • 27
    • 0028043535 scopus 로고
    • Signal transduction and regulation in smooth muscle
    • Somlyo AP & Somlyo AV. Signal transduction and regulation in smooth muscle. Nature 1994 372 231-236.
    • (1994) Nature , vol.372 , pp. 231-236
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 29
    • 0023787144 scopus 로고
    • Characterization of cyclic nucleotide and inositol-1,4,5-triphosphate-sensitive calcium-exchange activity of smooth muscle cells cultured from the human corpora cavernosa
    • Krall JF, Fittinoff M & Rajfer J. Characterization of cyclic nucleotide and inositol-1,4,5-triphosphate-sensitive calcium-exchange activity of smooth muscle cells cultured from the human corpora cavernosa. Biology of Reproduction 1988 39 913-922.
    • (1988) Biology of Reproduction , vol.39 , pp. 913-922
    • Krall, J.F.1    Fittinoff, M.2    Rajfer, J.3
  • 32
    • 0034991244 scopus 로고    scopus 로고
    • Cross talk between cyclic nucleotides and polyphosphoinositide hydrolysis, protein kinases, and contraction in smooth muscle
    • Abdel-Latif AA. Cross talk between cyclic nucleotides and polyphosphoinositide hydrolysis, protein kinases, and contraction in smooth muscle. Experimental Biology and Medicine 2001 226 153-163.
    • (2001) Experimental Biology and Medicine , vol.226 , pp. 153-163
    • Abdel-Latif, A.A.1
  • 33
    • 0032781886 scopus 로고    scopus 로고
    • Human vascular smooth muscle cells express a constitutive nitric oxide synthase that insulin rapidly activates, thus increasing guanosine 3′:5′-cyclic monophosphate and adenosine 3′:5′-cyclic monophosphate concentrations
    • Trovati M, Massucco P, Mattiello L, Costamagna C, Aldieri E, Cavalot F et al. Human vascular smooth muscle cells express a constitutive nitric oxide synthase that insulin rapidly activates, thus increasing guanosine 3′:5′-cyclic monophosphate and adenosine 3′:5′-cyclic monophosphate concentrations. Diabetologia 1999 42 831-839.
    • (1999) Diabetologia , vol.42 , pp. 831-839
    • Trovati, M.1    Massucco, P.2    Mattiello, L.3    Costamagna, C.4    Aldieri, E.5    Cavalot, F.6
  • 34
    • 0027364246 scopus 로고
    • Organic nitrates and compounds that increase intraplatelet cyclic guanosine monophosphate (cGMP) levels enhance the anti-aggregating effects of the stable prostacyclin analogue Iloprost
    • Anfossi G, Massucco P, Mularoni E, Cavalot F, Mattiello L & Trovati M. Organic nitrates and compounds that increase intraplatelet cyclic guanosine monophosphate (cGMP) levels enhance the anti-aggregating effects of the stable prostacyclin analogue Iloprost. Prostaglandins, Leukotrienes and Essential Fatty Acids 1993 49 839-845.
    • (1993) Prostaglandins, Leukotrienes and Essential Fatty Acids , vol.49 , pp. 839-845
    • Anfossi, G.1    Massucco, P.2    Mularoni, E.3    Cavalot, F.4    Mattiello, L.5    Trovati, M.6
  • 35
    • 0027948222 scopus 로고
    • Effect of forskolin and organic nitrates on aggregation and intracellular cyclic nucleotide content in human platelets
    • Anfossi G, Massucco P, Mularoni E, Cavalot F, Mattiello L & Trovati M. Effect of forskolin and organic nitrates on aggregation and intracellular cyclic nucleotide content in human platelets. General Pharmacology 1994 25 1093-1100.
    • (1994) General Pharmacology , vol.25 , pp. 1093-1100
    • Anfossi, G.1    Massucco, P.2    Mularoni, E.3    Cavalot, F.4    Mattiello, L.5    Trovati, M.6
  • 36
    • 0025314048 scopus 로고
    • Molecular basis of the synergistic inhibition of platelet function by nitrovasodilators and activators of adenylate cyclase: Inhibition of cyclic AMP breakdown by cyclic GMP
    • Maurice DH & Haslam RJ. Molecular basis of the synergistic inhibition of platelet function by nitrovasodilators and activators of adenylate cyclase: inhibition of cyclic AMP breakdown by cyclic GMP. Molecular Pharmacology 1990 37 671-681.
    • (1990) Molecular Pharmacology , vol.37 , pp. 671-681
    • Maurice, D.H.1    Haslam, R.J.2
  • 37
    • 0017384322 scopus 로고
    • Formation of adenosine 3′,5′-monophosphate by preparations of guanylate cyclase from rat liver and other tissues
    • Mittal KC & Murad F. Formation of adenosine 3′,5′-monophosphate by preparations of guanylate cyclase from rat liver and other tissues. Journal of Biological Chemistry 1977 252 3136-3140.
    • (1977) Journal of Biological Chemistry , vol.252 , pp. 3136-3140
    • Mittal, K.C.1    Murad, F.2
  • 38
    • 0029096571 scopus 로고
    • Insulin increases cyclic nucleotide content in human vascular smooth muscle cells: A mechanism potentially involved in insulin-induced modulation of vascular tone
    • Trovati M, Massucco P, Mattiello L, Cavalot F, Mularoni E, Hahn A et al. Insulin increases cyclic nucleotide content in human vascular smooth muscle cells: a mechanism potentially involved in insulin-induced modulation of vascular tone. Diabetologia 1995 38 936-941.
    • (1995) Diabetologia , vol.38 , pp. 936-941
    • Trovati, M.1    Massucco, P.2    Mattiello, L.3    Cavalot, F.4    Mularoni, E.5    Hahn, A.6
  • 39
    • 0029782271 scopus 로고    scopus 로고
    • Studies on the influence of insulin on cyclic adenosine monophosphate in human vascular smooth muscle cells: Dependence on cyclic guanosine monophosphate and modulation of catecholamine effects
    • Trovati M, Massucco P, Mattiello L, Cavalot F, Mularoni EM, Hahn AW et al. Studies on the influence of insulin on cyclic adenosine monophosphate in human vascular smooth muscle cells: dependence on cyclic guanosine monophosphate and modulation of catecholamine effects. Diabetologia 1996 39 1156-1164.
    • (1996) Diabetologia , vol.39 , pp. 1156-1164
    • Trovati, M.1    Massucco, P.2    Mattiello, L.3    Cavalot, F.4    Mularoni, E.M.5    Hahn, A.W.6
  • 40
    • 0028030813 scopus 로고
    • Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release
    • Steinberg HO, Brechtel G, Johnson A, Fineberg N & Baron A. Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release. Journal of Clinical Investigation 1994 94 1172-1179.
    • (1994) Journal of Clinical Investigation , vol.94 , pp. 1172-1179
    • Steinberg, H.O.1    Brechtel, G.2    Johnson, A.3    Fineberg, N.4    Baron, A.5
  • 42
    • 0029789432 scopus 로고    scopus 로고
    • Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells
    • Zeng G & Quon MJ. Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells. Journal of Clinical Investigation 1996 98 894-898.
    • (1996) Journal of Clinical Investigation , vol.98 , pp. 894-898
    • Zeng, G.1    Quon, M.J.2
  • 43
    • 15444357865 scopus 로고    scopus 로고
    • Insulin stimulates nitric oxide synthesis in human platelets and, through nitric oxide, increases platelet concentrations of both guanosine-3′,5′-cyclic monophosphate and adenosine-3′,5′-cyclic monophosphate
    • Trovati M, Anfossi G, Massucco P, Mattiello L, Costamagna C, Piretto V et al. Insulin stimulates nitric oxide synthesis in human platelets and, through nitric oxide, increases platelet concentrations of both guanosine-3′,5′-cyclic monophosphate and adenosine-3′,5′-cyclic monophosphate. Diabetes 1997 46 742-749.
    • (1997) Diabetes , vol.46 , pp. 742-749
    • Trovati, M.1    Anfossi, G.2    Massucco, P.3    Mattiello, L.4    Costamagna, C.5    Piretto, V.6
  • 44
    • 0031978604 scopus 로고    scopus 로고
    • Evidence for the involvement of endothelial nitric oxide synthase from smooth muscle cells in the erectile function of the corpus cavernosum
    • Bloch W, Klotz T, Sedleczek P, Zumbe J, Engelmann U & Addicks K. Evidence for the involvement of endothelial nitric oxide synthase from smooth muscle cells in the erectile function of the corpus cavernosum. Urological Research 1998 26 129-135.
    • (1998) Urological Research , vol.26 , pp. 129-135
    • Bloch, W.1    Klotz, T.2    Sedleczek, P.3    Zumbe, J.4    Engelmann, U.5    Addicks, K.6
  • 45
    • 0034938220 scopus 로고    scopus 로고
    • Immunocytochemical distribution of nitric oxide synthase in the human corpus cavernosum: An electron microscopical study using the tyramide signal amplification technique
    • Stanarius A, Uckert S, Machtens SA, Stief CG, Wolf G & Jonas U. Immunocytochemical distribution of nitric oxide synthase in the human corpus cavernosum: an electron microscopical study using the tyramide signal amplification technique. Urological Research 2001 29 168-172.
    • (2001) Urological Research , vol.29 , pp. 168-172
    • Stanarius, A.1    Uckert, S.2    Machtens, S.A.3    Stief, C.G.4    Wolf, G.5    Jonas, U.6
  • 47
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chlorophorm extraction
    • Chomczynski P & Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chlorophorm extraction. Analytical Biochemistry 1987 162 156-159.
    • (1987) Analytical Biochemistry , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 50
    • 0024491211 scopus 로고
    • A novel citrulline-forming enzyme implicated in the formation of nitric oxide by vascular endothelial cells
    • Palmer RMJ, Ferrige AG & Moncada S. A novel citrulline-forming enzyme implicated in the formation of nitric oxide by vascular endothelial cells. Biochemical and Biophysical Research Communications 1989 158 348-352.
    • (1989) Biochemical and Biophysical Research Communications , vol.158 , pp. 348-352
    • Palmer, R.M.J.1    Ferrige, A.G.2    Moncada, S.3
  • 51
    • 0029967490 scopus 로고    scopus 로고
    • Forskolin: A promising new adjunct to intracavernous pharmacotherapy
    • Cahn D, Melman A, Valcic, M & Christ GJ. Forskolin: a promising new adjunct to intracavernous pharmacotherapy. Journal of Urology 1996 155 1789-1794.
    • (1996) Journal of Urology , vol.155 , pp. 1789-1794
    • Cahn, D.1    Melman, A.2    Valcic, M.3    Christ, G.J.4
  • 52
    • 0030796819 scopus 로고    scopus 로고
    • Intracavernosal forskolin: Role in management of vasculogenic impotence resistant to standard 3-agent pharmacotherapy
    • Mulhall JP, Daller M, Traish AM, Gupta S, Park K, Salimpour P et al. Intracavernosal forskolin: role in management of vasculogenic impotence resistant to standard 3-agent pharmacotherapy. Journal of Urology 1997 158 1752-1758.
    • (1997) Journal of Urology , vol.158 , pp. 1752-1758
    • Mulhall, J.P.1    Daller, M.2    Traish, A.M.3    Gupta, S.4    Park, K.5    Salimpour, P.6


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