Which factors influence cognitive decline in older adults suffering from dementing disorders?

International Journal of Geriatric Psychiatry

Volumn 17, Issue 11, 2002, Pages 1055-1063

  Schäufele, Martina ^a   Bickel, Horst ^b   Weyerer, Siegfried ^a  

^a CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Dementia; Old age; Predictors of cognitive decline; Primary care; Prospective longitudinal design

Indexed keywords

ANTICOAGULANT AGENT; ANTIDEPRESSANT AGENT; HYPNOTIC SEDATIVE AGENT; NEUROLEPTIC AGENT; NOOTROPIC AGENT; PSYCHOTROPIC AGENT; TRANQUILIZER;

AGE; AGED; ARTICLE; BRADYKINESIA; CLINICAL EXAMINATION; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DEMENTIA; DEMOGRAPHY; DEPRESSION; DISEASE COURSE; DISEASE DURATION; DISEASE SEVERITY; ELDERLY CARE; FACTORIAL ANALYSIS; FEMALE; FOLLOW UP; GENDER; GENERAL PRACTITIONER; HIERARCHIC DEMENTIA SCALE; HUMAN; INTERVIEW; LANGUAGE DISABILITY; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MENTAL DETERIORATION; MORTALITY; MOTOR DYSFUNCTION; NEUROLOGIC DISEASE; PHYSICAL DISEASE; PREDICTION; PROBABILITY; PROGNOSIS; PROSPECTIVE STUDY; PSYCHOLOGIC ASSESSMENT; RANDOMIZATION; RATING SCALE; SOCIAL STATUS; STRATIFICATION; STROKE; SURVIVAL RATE; TREMOR;

AGED; AGED, 80 AND OVER; COGNITION DISORDERS; DEMENTIA; FEMALE; FOLLOW-UP STUDIES; HUMANS; LONGITUDINAL STUDIES; MALE; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 0036849701     PISSN: 08856230     EISSN: None     Source Type: Journal    
DOI: 10.1002/gps.748     Document Type: Article

References (43)

1. Agüero-Torres H, Fratiglioni L, Winblad B. 1998a. Natural history of Alzheimer's disease and other dementias: review of the literature in the light of the findings from the Kungsholmen project. Int J Geriatr Psychiatry 13: 755-766.
2. Agüero-Torres H, Fratiglioni L, Guo Z, Viitanen M, Winblad B. 1998b. Prognostic factors in very old demented adults: a seven-year follow-up from a population-based survey in Stockholm. J Am Geriatr Soc 46: 444-452.
3. Ballard C, O'Brien J, Morris CM, Barber R, Swann A, Neill D, McKeith I. 2001. The progression of cognitive impairment in dementia with Lewy bodies, vascular dementia and Alzheimer's disease. Int J Geriatr Psychiatry 16: 499-503.
4. Bickel H. 1996. The Hierarchic Dementia Scale: usage. Int Psychogeriatr 8(2): 213-224.
5. Bracco L, Gallato R, Grigoletto F, Lippi A, Lepore V, Bino G, Lazzaro MP, Carella F, Piccolo T, Pozzilli C, Giometto B, Amaducci L. 1994. Factors affecting course and survival in Alzheimer's disease: a 9-year longitudinal study. Arch Neurol 51: 1213-1219.
6. Bracco L, Piccini C, Amaducci L. 1998. Rate of progression of mental decline in Alzheimer disease: summary of European studies. Alzheimer Dis Assoc Disord 12: 347-355.
7. Bundesministerium für Familie, Senioren, Frauen und Jugend (eds). 2002. Vierter Bericht zur Lage der älteren Generation in der Bundesrepublik Deutschland. Risiken, Lebensqualität und Versorgung Hochaltriger, unter besonderer Berücksichtigung demenzieller Erkrankungen. Eigendruck: Berlin.
8. Burns A, Jacoby R, Levy R. 1991. Progression of cognitive impairment in Alzheimer's disease. J Am Geriatr Soc 39: 39-45.
9. Chui HC, Lyness SA, Sobel E, Schneider LS. 1994. Extrapyramidal signs and psychiatric symptoms predict faster cognitive decline in Alzheimer's disease. Arch Neurol 51: 676-681.
10. Chui HC, Gonthier R. 1999. Natural history of vascular dementia. Alzheimer Dis Assoc Disord 13(Suppl. 3): 124-134.
11. Cole MG, Dastoor DP. 1987. A new hierarchic approach to the measurement of dementia. Psychosomatics 28: 298-304.
12. Cooper B, Bickel H, Schäufele M. 1996. Early development and progression of dementing illness in the elderly: a general-practice based study. Psychol Med 26: 411-419.
13. Corey-Bloom J, Galasko D, Hofstetter R, Jackson JE, Thal LJ. 1993. Clinical features distinguishing large cohorts with possible AD, probable AD, and mixed dementia. J Am Geriatr Soc 41: 31-37.
14. Del Ser T, Hachinski V, Merskey H, Munoz DG. 1999. An autopsy-verified study of the effect of education on degenerative dementia. Brain 122: 2309-2919.
15. Folstein MF, Folstein SE, McHugh PR. 1975. 'Mini-Mental State': a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12: 189-198.
16. Förstl H, Sattel H, Besthorn C, Daniel S, Geiger-Kabisch C, Hentschel F, Sarochan M, Zerfaß R. 1996. Longitudinal, cognitive, electroencephalographic and morphological brain changes in ageing and Alzheimer's disease. Br J Psychiatry 168: 280-286.
17. Galasko D, Edland SD, Morris JC, Clark C, Mohs R, Koss E. 1995. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part XI. Clinical milestones in patients with Alzheimer's disease followed over 3 years. Neurology 45: 1451-1455.
18. Geerlings MI, Deeg DJ, Schmand B, Lindeboom J, Jonker C. 1997. Increased risk of mortality in Alzheimer's disease patients with higher education? A replication study. Neurology 49: 798-802.
19. Green CR, Mohs RC, Schmeidler J, Aryan M, Davis KL. 1993. Functional decline in Alzheimer's disease: a longitudinal study. J Am Geriatr Soc 41: 654-661.
20. Hamilton M. 1967. Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol 6: 278-296.
21. Han L, Cole M, Bellavance F, McCusker J, Primeau F. 2000. Tracking cognitive decline in Alzheimer's disease using the Mini-Mental State Examination: a meta-analysis. Int Psychogeriatr 12: 231-247.
22. Jacobs D, Sano M, Marder K. 1994. Age at onset of Alzheimer's disease: relation to patterns of dysfunction and rate of decline. Neurology 44: 1215-1220.
23. Kraemer HC, Tinklenberg J, Yesavage JA. 1994. 'How far' vs 'how fast' in Alzheimer's disease. Arch Neurol 51: 275-279.
24. Lopez OL, Wisniewski SR, Becker JT, Boller F, DeKosky ST. 1997. Extrapyramidal signs in patients with probable Alzheimer's disease. Arch Neurol 58: 969-975.
25. Lopez OL, Wisniewski SR, Becker JT, Boller F, DeKosky ST. 1999. Psychiatric medication and abnormal behavior as predictors of progression in probable Alzheimer disease. Arch Neurol 56: 1266-1272.
26. Lucca U, Comelli M, Tettamanti M, Tiraboschi P, Spagnoli A. (1993) Rate of progression and prognostic factors in Alzheimer's disease: a prospective study. J Am Geriatr Soc 41: 45-49.
27. Mayeux R, Stern Y, Spanton S. 1985. Heterogeneity in dementia of the Alzheimer type: evidence of subgroups. Neurology 35: 53-61.
28. McShane R, Keene J, Gedling K, Fairburn C, Jacoby R, Hope T. 1997. Do neuroleptic drugs hasten cognitive decline in dementia? Prospective study with necropsy follow up. BMJ 314: 266-270.
29. Morris JC, Edland S, Clark C, Galasko D, Koss E, Mohs R, van Belle G, Fillenbaum G, Heyman A. 1993. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part IV. Rates of cognitive change in the longitudinal assessment of probable Alzheimer's disease. Neurology 43: 2457-2465.
30. Mortimer JA, Ebbitt B, Jun S-P, Finch MD. 1992. Predictors of cognitive and functional progression in patients with probable Alzheimer's disease. Neurology 42: 1689-1696.
31. Nielsen H, Lolk A, Pedersen I, Autzen M, Sennef C, Kragh-Sörensen P. 1991. The accuracy of early diagnosis and predictors of death in Alzheimer's disease and vascular dementia - a follow-up study. Acta Psychiatr Scand 84: 277-282.
32. O'Connor DW, Pollitt PA, Hyde JB, Fellowes JL, Miller ND, Roth M. 1991. The progression of mild idiopathic dementia in a community population. J Am Geriatr Soc 39: 246-251.
33. Roth M, Tym E, Mountjoy CQ, Huppert FA, Hendrie H, Verma S, Goddard R. 1986. CAMDEX: a standardised instrument for the diagnosis of mental disorders in the elderly with special reference to the early detection of dementia. Br J Psychiatry 149: 698-709.
34. Sandholzer H. 1982. Measuring impairment and disability in the elderly: a study in general practice. Soc Psychiatry 17: 189-198.
35. Schäufele M, Bickel H, Weyerer S. 1999. Predictors of mortality among demented elderly in primary care. Int J Geriatr Psychiatry 14: 946-956.
36. Slooter AJC, Houwing-Duistermaat JJ, van Harskamp F, Cruts M, Van Broeckhoven C, Breteler MB, Hofman A, Stijnen T, van Duijn CM. 1999. Apolipoprotein E genotype and progression of Alzheimer's disease: the Rotterdam study. J Neurol 246: 304-308.
37. Stern RG, Mohs RC, Davidson M, Schmeidler J, Silverman J, Kramer-Ginsberg E, Searcey T, Bierer L, Davis KL. 1994. A longitudinal study of Alzheimer's disease: measurement, rate, and predictors of cognitive deterioration. Am J Psychiatry 151: 390-396.
38. Stern Y, Albert S, Tang M-X, Tsai W-Y. 1999. Rate of memory decline in AD is related to education and occupation. Cognitive reserve? Neurology 53: 1942-1947.
39. Stern Y. 2000. Predicting time to nursing home care and death in individuals with Alzheimer's disease http://cpmcnet.columbia.edu/dept/sergievsky/predictor/html
40. Teri L, Hughes JP, Larson EB. 1990. Cognitive deterioration in Alzheimer's disease: behavioral and health factors. J Gerontol 45: P58-P63.
41. Teri L, McCurry SM, Edland SD, Kukull WA, Larson EB. 1995. Cognitive decline in Alzheimer's disease: a longitudinal investigation of risk factors for accelerated decline. J Gerontol Biol Sci Med Sci 50A: M49-M55.
42. Weiner MF, Vega G, Risser RC, Honig LS, Cullum CM, Crumpacker D, Rosenberg RN. 1999. Apolipoprotein Eε4, other risk factors, and course of Alzheimer's disease. Biol Psychiatry 45: 633-638.
43. Yesavage JA, Brooks JO, III, Taylor J, Tinklenberg J. 1993. Development of aphasia, apraxia, and agnosia and decline in Alzheimer's disease. Am J Psychiatry 150: 742-747.